Search Results - "Asai, Toshihiro"

NARIRUTIN INHIBITS AIRWAY INFLAMMATION IN AN ALLERGIC MOUSE MODEL by Funaguchi, Norihiko, Ohno, Yasushi, La, Bu Lin Bai, Asai, Toshihiro, Yuhgetsu, Hideyuki, Sawada, Masahiro, Takemura, Genzou, Minatoguchi, Shinya, Fujiwara, Takako, Fujiwara, Hisayoshi

“…SUMMARY 1 Flavonoids are naturally occurring compounds that possess anti‐allergic, anti‐inflammatory, antiproliferative and anti‐oxidant properties. In the…”
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Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: The Role of Nuclear Factor κB Activation in the Development of Renal Fibrosis by Tamada, Satoshi, Asai, Toshihiro, Kuwabara, Nobuyuki, Iwai, Tomoaki, Uchida, Junji, Teramoto, Kae, Kaneda, Noriko, Yukimura, Tokihito, Komiya, Toshiyuki, Nakatani, Tatsuya, Miura, Katsuyuki

“…Tubulointerstitial fibrosis is a common feature of many progressive renal diseases and is a main determinant that leads to an irreversible loss of renal…”
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Anti-tumor effect of gallic acid on LL-2 lung cancer cells transplanted in mice by Kawada, Miki, Ohno, Yasushi, Ri, Yunmo, Ikoma, Tetsuro, Yuugetu, Hideyuki, Asai, Toshihiro, Watanabe, Motohiro, Yasuda, Norio, Akao, Seigou, Takemura, Genzou, Minatoguchi, Shinya, Gotoh, Kohshi, Fujiwara, Hisayoshi, Fukuda, Kazunori

“…We previously reported that gallic acid (3,4,5-trihydroxybenzoic acid), a naturally occurring plant phenol, can induce apoptosis in four kinds of human lung…”
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Pharmacokinetic Study of Interleukin-2 Following Intravenous Injection in Hemodialysis Patients With Renal Cell Carcinoma by Kamikawa, Sadanori, Sugimoto, Toshikado, Asai, Toshihiro, Ishii, Keiichi, Kim, Taku

“…:  The purpose of the present study is to determine the change in blood concentration of interleukin‐2 (IL‐2) after intravenous injection in hemodialysis…”
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Magnesium supplementation prevents experimental chronic cyclosporine A nephrotoxicity via renin-angiotensin system independent mechanism by ASAI, Toshihiro, NAKATANI, Tatsuya, MIURA, Katsuyuki, YAMANAKA, Shinya, TAMADA, Satoshi, KISHIMOTO, Taketoshi, TASHIRO, Koichiro, NAKAO, Takafumi, OKAMURA, Mikio, KIM, Shokei, IWAO, Hiroshi

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Molecular mechanisms and therapeutic strategies of chronic renal injury: the role of nuclear factor kappaB activation in the development of renal fibrosis by Tamada, Satoshi, Asai, Toshihiro, Kuwabara, Nobuyuki, Iwai, Tomoaki, Uchida, Junji, Teramoto, Kae, Kaneda, Noriko, Yukimura, Tokihito, Komiya, Toshiyuki, Nakatani, Tatsuya, Miura, Katsuyuki

“…Tubulointerstitial fibrosis is a common feature of many progressive renal diseases and is a main determinant that leads to an irreversible loss of renal…”
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Non-immunologic factor: immunosuppressive drug-induced nephrotoxicity by Nakatani, Tatsuya, Asai, Toshihiro

“…Immunosuppressant-induced nephrotoxicity contributes to kidney graft loss in the long-term as one of the non-immunologic factors. We previously reported that…”
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ROLE OF HYPOMAGNESEMIA IN CHRONIC CYCLOSPORINE NEPHROPATHY1 by Miura, Katsuyuki, Nakatani, Tatsuya, Asai, Toshihiro, Yamanaka, Shinya, Tamada, Satoshi, Tashiro, Koichiro, Kim, Shokei, Okamura, Mikio, Iwao, Hiroshi

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A multi-institutional, observational study of outcomes after catheter placement for peritoneal dialysis in Japan by Sakurada, Tsutomu, Kojima, Shigeki, Yamada, Shohei, Koitabashi, Kenichiro, Taki, Yasuhiro, Matsui, Katsuomi, Murasawa, Masaru, Kawarazaki, Hiroo, Shimizu, Sayaka, Kobayashi, Hironori, Asai, Toshihiro, Hashimoto, Koji, Hoshino, Taro, Sugitani, Seita, Maoka, Tomochika, Nagase, Akihiko, Sato, Hirotaka, Fukuoka, Kosuke, Sofue, Tadashi, Koibuchi, Kiyoto, Nagayama, Kiyomitsu, Washida, Naoki, Koide, Shigehisa, Okamoto, Takayuki, Ishii, Daisuke, Furukata, Satoshi, Uchiyama, Kiyotaka, Takahashi, Shunsuke, Nishizawa, Yoshiko, Naito, Shotaro, Toda, Naohiro, Naganuma, Tsukasa, Kikuchi, Hidetoshi, Suzuki, Tomo, Komukai, Daisuke, Kimura, Takahide, Io, Hiroaki, Yoshikawa, Kazuhiro, Naganuma, Toshihide, Morishita, Masamitsu, Oshikawa, Jin, Tamagaki, Keiichi, Fujisawa, Hajime, Ueda, Atsushi, Kanaoka, Tomohiko, Nakamura, Hironori, Yanagi, Mai, Udagawa, Takashi, Yoneda, Tatsuo, Sakai, Masashi, Gunji, Masanobu, Osaki, Shinichi, Saito, Hisako, Yoshioka, Yuuki, Kaneshiro, Nagayuki

“…Background: This multi-institutional, observational study examined whether the outcomes after peritoneal dialysis (PD) catheter placement in Japan meet the…”
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Benefits and Risks of Introduction of Everolimus in Long-Term Kidney Transplant Recipients by Asai, Toshihiro, Tanaka, Hisao, Nishikawa, Noriaki, Hasaka, Tomohiro, Kitamoto, Koichiro, Ishii, Keiichi, Kamikawa, Sadanori, Sugimoto, Toshikado, Kim, Taku, Kumada, Norihiko

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Single-Allele Correction Of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat by Watanabe, Takeshi K, Okuno, Shiro, Ono, Toshihide, Yamasaki, Yuki, Oga, Keiko, Mizoguchi-Miyakita, Ayako, Miyao, Hideo, Suzuki, Mikio, Momota, Hiroshi, Goto, Yoshihiro, Shinomiya, Hiroichi, Hishigaki, Haretsugu, Hayashi, Isamu, Asai, Toshihiro, Wakitani, Shigeyuki, Takagi, Toshihisa, Nakamura, Yusuke, Tanigami, Akira

“…SUMMARY 1. Whole‐genome scans have identified Dmo1 as a major quantitative trait locus for dyslipidaemia and obesity in the Otsuka Long Evans Tokushima Fatty…”
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Attenuation of renal fibrosis by proteasome inhibition in rat obstructive nephropathy: possible role of nuclear factor kappaB by Tashiro, Koichiro, Tamada, Satoshi, Kuwabara, Nobuyuki, Komiya, Toshiyuki, Takekida, Kaori, Asai, Toshihiro, Iwao, Hiroshi, Sugimura, Kazunobu, Matsumura, Yasuo, Takaoka, Masanori, Nakatani, Tatsuya, Miura, Katsuyuki

“…We previously reported that pyrrolidine dithiocarbamate blocked nuclear factor-kappaB (NF-kappaB) activation and attenuated interstitial inflammation and…”
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THE SPECIFIC FREE RADICAL SCAVENGER EDARAVONE SUPPRESSES BLEOMYCIN-INDUCED ACUTE PULMONARY INJURY IN RABBITS by Asai, Toshihiro, Ohno, Yasushi, Minatoguchi, Shinya, Funaguchi, Norihiko, Yuhgetsu, Hideyuki, Sawada, Masahiro, Takemura, Genzou, Komada, A, Fujiwara, Takako, Fujiwara, Hisayoshi

“…SUMMARY 1 Intratracheal instillation of bleomycin induces a condition in rabbits that serves as a useful model of human pulmonary fibrosis. Bleomycin‐induced…”
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Role of hypomagnesemia in chronic cyclosporine nephropathy by MIURA, Katsuyuki, NAKATANI, Tatsuya, ASAI, Toshihiro, YAMANAKA, Shinya, TAMADA, Satoshi, TASHIRO, Koichiro, KIM, Shokei, OKAMURA, Mikio, IWAO, Hiroshi

“…Hypomagnesemia is a common finding of cyclosporine (CsA)-treated patients and has been proposed as both a cause and a consequence of CsA-induced…”
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Magnesium supplementation prevents experimental chronic cyclosporine a nephrotoxicity via renin-angiotensin system independent mechanism by Asai, Toshihiro, Nakatani, Tatsuya, Yamanaka, Shinya, Tamada, Satoshi, Kishimoto, Taketoshi, Tashiro, Koichiro, Nakao, Takafumi, Okamura, Mikio, Kim, Shokei, Iwao, Hiroshi, Miura, Katsuyuki

“…We have previously shown that correction of hypomagnesemia by magnesium (Mg) supplementation ameliorates chronic cyclosporine A (CsA) nephropathy via…”
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Inhibition of nuclear factor-κB activation by pyrrolidine dithiocarbamate prevents chronic FK506 nephropathy by Tamada, Satoshi, Nakatani, Tatsuya, Asai, Toshihiro, Tashiro, Koichiro, Komiya, Toshiyuki, Sumi, Tomohiko, Okamura, Mikio, Kim, Shokei, Iwao, Hiroshi, Kishimoto, Taketoshi, Yamanaka, Shinya, Miura, Katsuyuki

“…Inhibition of nuclear factor-κB activation by pyrrolidine dithiocarbamate prevents chronic FK506 nephropathy. Chronic tacrolimus (FK506) nephrotoxicity is…”
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Role of Renin-Angiotensin System and Nuclear Factor-κB in the Obstructed Kidney of Rats With Unilateral Ureteral Obstruction by Nakatani, Tatsuya, Tamada, Satoshi, Asai, Toshihiro, Iwai, Yoshihito, Kim, Taku, Tsujino, Takashi, Kumata, Norihiko, Uchida, Junji, Tashiro, Koichiro, Kuwabara, Nobuyuki, Komiya, Toshiyuki, Sumi, Tomohiko, Okamura, Mikio, Miura, Katsuyuki

“…The present study was conducted to elucidate the role of oxidative stress and nuclear factor-?B (NF-?B) in the beneficial effects of angiotensin receptor…”
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Activation of transcription factors AP-1 and NF-κB in chronic cyclosporine A nephrotoxicity: Role in beneficial effects of magnesium supplementation by ASAI, Toshihiro, NAKATANI, Tatsuya, IWAO, Hiroshi, MIURA, Katsuyuki, TAMADA, Satoshi, KUWABARA, Nobuyuki, YAMANAKA, Shinya, TASHIRO, Koichiro, NAKAO, Takafumi, KOMIYA, Toshiyuki, OKAMURA, Mikio, KIM, Shokei

“…Background. It has been shown that the transcription factors activator protein (AP)-1 and nuclear factor (NF)- Kappa B play a pivotal role in various renal…”
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THE FAS FAS-LIGAND PATHWAY DOES NOT MEDIATE THE APOPTOSIS IN ELASTASE-INDUCED EMPHYSEMA IN MICE by Sawada, Masahiro, Ohno, Yasushi, La, Bu Lin Bai, Funaguchi, Norihiko, Asai, Toshihiro, Yuhgetsu, Hideyuki, Takemura, Genzou, Minatoguchi, Shinya, Fujiwara, Hisayoshi, Fujiwara, Takako

“…Porcine pancreatic elastase (PPE), which induces emphysema via apoptosis, was administered to wild-type and Fas-deficient (lpr) mice. On days 3 and 28 after…”
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Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain by Okuno, S, Watanabe, T K, Ono, T, Oga, K, Mizoguchi-Miyakita, A, Yamasaki, Y, Goto, Y, Shinomiya, H, Momota, H, Miyao, H, Hayashi, I, Asai, T, Suzuki, M, Harada, Y, Hishigaki, H, Wakitani, S, Takagi, T, Nakamura, Y, Tanigami, A

“…Whole-genome scans have identified Dmo1 as a major quantitative trait locus (QTL) for obesity and dyslipidaemia in the Otsuka Long Evans Tokushima Fatty…”
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