Search Results - "Asaf, Roy"
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Fecal microbial characterization of hospitalized patients with suspected infectious diarrhea shows significant dysbiosis
Published in Scientific reports (24-04-2017)“…Hospitalized patients are at increased risk for acquiring healthcare-associated infections (HAIs) and inadequate nutrition. The human intestinal microbiota…”
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Correction of HDL Dysfunction in Individuals With Diabetes and the Haptoglobin 2-2 Genotype
Published in Diabetes (New York, N.Y.) (01-10-2008)“…Correction of HDL Dysfunction in Individuals With Diabetes and the Haptoglobin 2-2 Genotype Rabea Asleh 1 , Shany Blum 1 , Shiri Kalet-Litman 1 , Jonia Alshiek…”
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Haptoglobin Genotype Is a Determinant of Iron, Lipid Peroxidation, and Macrophage Accumulation in the Atherosclerotic Plaque
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2007)“…OBJECTIVE—Intraplaque hemorrhage increases the risk of plaque rupture and thrombosis. The release of hemoglobin (Hb) from extravasated erythrocytes at the site…”
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Haptoglobin genotype is a determinant of survival and cardiac remodeling after myocardial infarction in diabetic mice
Published in Cardiovascular diabetology (02-06-2009)“…We have recently demonstrated in man that a functional allelic polymorphism in the Haptoglobin (Hp) gene plays a major role in determining survival and…”
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Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus
Published in Diabetes/metabolism research and reviews (01-07-2005)“…Background The human haptoglobin (Hp) gene is polymorphic with two functional classes of alleles, denoted 1 and 2. We have demonstrated in three longitudinal…”
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Haptoglobin: basic and clinical aspects
Published in Antioxidants & redox signaling (15-01-2010)“…Haptoglobin is an abundant hemoglobin-binding protein present in the plasma. The function of haptoglobin is primarily to determine the fate of hemoglobin…”
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Testicular failure in a patient with G6PC3 deficiency
Published in Pediatric research (01-08-2014)“…Background: Glucose-6-phosphatase-β (G6PC3) deficiency is characterized by congenital neutropenia and variable developmental disorders, including those of the…”
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Vitamin E therapy results in a reduction in HDL function in individuals with diabetes and the haptoglobin 2-1 genotype
Published in Atherosclerosis (01-11-2011)“…Abstract Objective Vitamin E provides cardiovascular protection to individuals with diabetes and the haptoglobin 2-2 genotype but appears to increase…”
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Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus
Published in American journal of physiology. Renal physiology (01-04-2009)“…Polymorphic loci regulating oxidative stress are potential susceptibility genes for diabetic nephropathy (DN). Haptoglobin (Hp) is an antioxidant protein which…”
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Haptoglobin Genotype Determines Myocardial Infarct Size in Diabetic Mice
Published in Journal of the American College of Cardiology (02-01-2007)“…Haptoglobin Genotype Determines Myocardial Infarct Size in Diabetic Mice Shany Blum, Roy Asaf, Julia Guetta, Rachel Miller-Lotan, Rabea Asleh, Ran Kremer, Nina…”
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Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus
Published in Diabetes/metabolism research and reviews (01-02-2007)“…Background Individuals with diabetes mellitus (DM) homozygous for the haptoglobin (Hp) 1 allele are at decreased risk of retinopathy as compared to DM…”
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Abstract 601: Haptoglobin Genotype Determines Myocardial Infarct Size in Diabetic Mice
Published in Circulation (New York, N.Y.) (31-10-2006)“…Abstract only Objectives. We sought to understand the importance of oxidative stress in explaining why the haptoglobin (Hp) genotype determines myocardial…”
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