Search Results - "Asadzadeh, Zahra"
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Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death
Published in Cancers (23-04-2020)“…Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is increasing the susceptibility of cells to death. Cancer cells…”
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The paradox of Th17 cell functions in tumor immunity
Published in Cellular immunology (01-12-2017)“…•Th17 cells produce high level of IL-17 that have close association with tumorigenesis.•IL-17 cytokines are double-edged agents and depending on type of cancer…”
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The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV
Published in Archives of virology (01-03-2021)“…The number of descriptions of emerging viruses has grown at an unprecedented rate since the beginning of the 21 st century. Severe acute respiratory syndrome…”
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The Positive and Negative Immunoregulatory Role of B7 Family: Promising Novel Targets in Gastric Cancer Treatment
Published in International journal of molecular sciences (03-10-2021)“…Gastric cancer (GC), with a heterogeneous nature, is the third leading cause of death worldwide. Over the past few decades, stable reductions in the incidence…”
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The importance of immune checkpoints in immune monitoring: A future paradigm shift in the treatment of cancer
Published in Biomedicine & pharmacotherapy (01-02-2022)“…The growth and development of cancer are directly correlated to the suppression of the immune system. A major breakthrough in cancer immunotherapy depends on…”
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Alpha7 nicotinic acetylcholine receptors in lung inflammation and carcinogenesis: Friends or foes?
Published in Journal of cellular physiology (01-09-2019)“…The lung tissue expresses the cholinergic system including nicotinic acetylcholine receptors (nAChRs) which included in many physiologic and pathologic…”
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The oncogenic potential of NANOG: An important cancer induction mediator
Published in Journal of cellular physiology (01-04-2021)“…Cancer stem cells (CSCs) are a unique population in the tumor, but they only comprise 2%–5% of the tumor bulk. Although CSCs share several features with…”
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Signaling pathways and microRNAs, the orchestrators of NANOG activity during cancer induction
Published in Life sciences (1973) (01-11-2020)“…Cancer stem cells (CSCs) are a small part of cancer cells inside the tumor that have similar characteristics to normal stem cells. CSCs stimulate tumor…”
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The Analysis of Herpes Simplex Virus Type 1 (HSV-1)-Encoded MicroRNAs Targets: A Likely Relationship of Alzheimer's Disease and HSV-1 Infection
Published in Cellular and molecular neurobiology (01-11-2022)“…Alzheimer's disease (AD), the most frequently diagnosed dementia, is a senile neurodegenerative disorder characterized by amnesia and cognitive dysfunction…”
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HMGA2 and Bach‐1 cooperate to promote breast cancer cell malignancy
Published in Journal of cellular physiology (01-10-2019)“…During breast cancer progression, tumor cells acquire multiple malignant features. The transcription factors and cell cycle regulators high mobility group A2…”
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The cross-talk between tumor-associated macrophages and tumor endothelium: Recent advances in macrophage-based cancer immunotherapy
Published in Biomedicine & pharmacotherapy (01-02-2022)“…Tumor-associated macrophages (TAMs) are among the abundant cell populations of the tumor microenvironment (TME), which have pivotal roles in tumor development,…”
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The combination effect of Prominin1 (CD133) suppression and Oxaliplatin treatment in colorectal cancer therapy
Published in Biomedicine & pharmacotherapy (01-05-2021)“…Colorectal cancer (CRC) is considered one of the leading types of cancer in the world. CD133, as a cancer stem cell marker, has a pivotal role in the…”
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The Prognostic Value of CD133 in Predicting the Relapse and Recurrence Pattern of High-Grade Gliomas on MRI: A Meta-Analysis
Published in Frontiers in oncology (02-09-2021)“…Cancer stem cells have been implicated in tumor relapse, tumor invasion, and cancer therapy resistance in high-grade gliomas; thus, characterizing cancer stem…”
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A scoping review on the potentiality of PD-L1-inhibiting microRNAs in treating colorectal cancer: Toward single-cell sequencing-guided biocompatible-based delivery
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Tumoral programmed cell death ligand 1 (PD-L1) has been implicated in the immune evasion and development of colorectal cancer. Although monoclonal immune…”
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MicroRNAs and lncRNAs-A New Layer of Myeloid-Derived Suppressor Cells Regulation
Published in Frontiers in immunology (02-10-2020)“…Myeloid-derived suppressor cells (MDSCs) constitute an important component in regulating immune responses in several abnormal physiological conditions such as…”
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A Systematic Review and Meta-Analysis on the Significance of TIGIT in Solid Cancers: Dual TIGIT/PD-1 Blockade to Overcome Immune-Resistance in Solid Cancers
Published in International journal of molecular sciences (01-10-2021)“…Preclinical studies have indicated that T-cell immunoglobulin and ITIM domain (TIGIT) can substantially attenuate anti-tumoral immune responses. Although…”
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Immune Checkpoint Inhibitors in Colorectal Cancer: Challenges and Future Prospects
Published in Biomedicines (24-08-2021)“…Immunotherapy is a new pillar of cancer therapy that provides novel opportunities to treat solid tumors. In this context, the development of new drugs…”
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The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters
Published in Frontiers in immunology (24-08-2021)“…Although the exact pathophysiology of MS has not been identified, mitochondrial stress can be one of the culprits in MS development. Herein, we have applied…”
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A Systematic Review of the Tumor-Infiltrating CD8 + T-Cells/PD-L1 Axis in High-Grade Glial Tumors: Toward Personalized Immuno-Oncology
Published in Frontiers in immunology (17-09-2021)“…Based on preclinical findings, programmed death-ligand 1 (PD-L1) can substantially attenuate CD8 T-cell-mediated anti-tumoral immune responses. However,…”
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Targeting TGF-β-Mediated SMAD Signaling Pathway via Novel Recombinant Cytotoxin II: A Potent Protein from Naja naja oxiana Venom in Melanoma
Published in Molecules (Basel, Switzerland) (05-11-2020)“…Since the current treatments have not resulted in the desired outcomes for melanoma patients, there is a need to identify more effective medications. Together…”
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