Search Results - "Asada, H. Harry"
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Three-dimensionally printed biological machines powered by skeletal muscle
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-2014)“…Combining biological components, such as cells and tissues, with soft robotics can enable the fabrication of biological machines with the ability to sense,…”
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2
Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration
Published in Proceedings of the National Academy of Sciences - PNAS (16-01-2018)“…Filopodia have a key role in sensing both chemical and mechanical cues in surrounding extracellular matrix (ECM). However, quantitative understanding is still…”
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3
Utilization and control of bioactuators across multiple length scales
Published in Lab on a chip (01-01-2014)“…In this review, we summarize the recent developments in the emerging field of bioactuators across a multitude of length scales. First, we discuss the use and…”
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Formation and optogenetic control of engineered 3D skeletal muscle bioactuators
Published in Lab on a chip (07-12-2012)“…Densely arrayed skeletal myotubes are activated individually and as a group using precise optical stimulation with high spatiotemporal resolution. Skeletal…”
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5
Utility of the Photoplethysmogram in Circulatory Monitoring
Published in Anesthesiology (Philadelphia) (01-05-2008)“…The photoplethysmogram is a noninvasive circulatory signal related to the pulsatile volume of blood in tissue and is displayed by many pulse oximeters and…”
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Extracellular matrix remodelling induced by alternating electrical and mechanical stimulations increases the contraction of engineered skeletal muscle tissues
Published in Scientific reports (25-02-2019)“…Engineered skeletal muscles are inferior to natural muscles in terms of contractile force, hampering their potential use in practical applications. One major…”
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7
Inherent Haptic Feedback From Supernumerary Robotic Limbs
Published in IEEE transactions on haptics (01-01-2021)“…Supernumerary Robotics Limbs, or SuperLimbs for short, are wearable extra limbs for augmenting the wearer. SuperLimbs are attached directly to a human and,…”
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A computational modeling of invadopodia protrusion into an extracellular matrix fiber network
Published in Scientific reports (24-01-2022)“…Invadopodia are dynamic actin-rich membrane protrusions that have been implicated in cancer cell invasion and metastasis. In addition, invasiveness of cancer…”
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A process engineering approach to increase organoid yield
Published in Development (Cambridge) (15-03-2017)“…Temporal manipulation of the environment and growth factors can direct differentiation of human pluripotent stem cells into organoids - aggregates with…”
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Formation of elongated fascicle-inspired 3D tissues consisting of high-density, aligned cells using sacrificial outer molding
Published in Lab on a chip (01-01-2014)“…The majority of muscles, nerves, and tendons are composed of fiber-like fascicle morphology. Each fascicle has a) elongated cells highly aligned with the…”
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11
Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment
Published in Scientific reports (07-02-2014)“…Delta-like 4 (Dll4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. Dll4 is highly expressed in capillary…”
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Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures
Published in PloS one (25-05-2012)“…We demonstrate ensemble three-dimensional cell cultures and quantitative analysis of angiogenic growth from uniform endothelial monolayers. Our approach…”
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13
Enhancing Elderly Mobility: A Sturdy, Two-Body Robot for Handlebar Placement in Any Location
Published in IEEE robotics and automation letters (01-03-2024)“…Grab bars are widely used to provide elderly persons with support for daily activities, but their utility is limited by room geometry, cost of installation,…”
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14
A Handle Robot for Providing Bodily Support to Elderly Persons
Published in 2023 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (01-10-2023)“…Age-related loss of mobility and an increased risk of falling remain major obstacles for older adults to live independently. Many elderly people lack the…”
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Conference Proceeding -
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Data-Driven Encoding: A New Numerical Method for Computation of the Koopman Operator
Published in IEEE robotics and automation letters (01-07-2023)“…This paper presents a data-driven method for constructing a Koopman linear model based on the Direct Encoding (DE) formula. The prevailing methods, Dynamic…”
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16
A Model-Free Extremum-Seeking Approach to Autonomous Excavator Control Based on Output Power Maximization
Published in IEEE robotics and automation letters (01-04-2019)“…A new approach to autonomous excavator control that allows the machine to adapt to unknown soil properties is presented. Unlike traditional force control or…”
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Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network
Published in PLoS computational biology (01-10-2015)“…The dynamics of filopodia interacting with the surrounding extracellular matrix (ECM) play a key role in various cell-ECM interactions, but their mechanisms of…”
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Time-Critical Fall Prediction Based on Lipschitz Data Analysis and Design of a Reconfigurable Walker for Preventing Fall Injuries
Published in IEEE access (2024)“…Falls may cause serious injuries to older adults, leading to a deteriorated quality of life. Currently, there is a lack of fall injury prevention devices,…”
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Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices
Published in PloS one (14-11-2017)“…Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a critical step in cancer invasion. Better understanding of the angiogenic…”
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Empirical characterization of modular variable stiffness inflatable structures for supernumerary grasp-assist devices
Published in The International journal of robotics research (01-12-2017)“…This paper presents the design, fabrication, and experimental characterization of modular, variable stiffness inflatable components for pneumatically actuated…”
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