Search Results - "Aryal, Sameer"

Turning up translation in fragile X syndrome by Aryal, Sameer, Klann, Eric

“…Fragile X mental retardation protein promotes translation, contrary to its assumed function Fragile X syndrome (FXS) is the most prevalent inherited form of…”
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Fine Needle Aspiration Cytology of Pancreatoblastoma in Adult/Adolescent Patients, One With Histology Mimicking NUT Carcinoma by Xu, Zhengfan, Aryal, Sameer Chhetri, McHugh, Kelsey, Theisen, Brian K, Yuan, Lisi

“…Pancreatoblastoma is a rare malignant neoplasm. Cytologic diagnosis is challenging due to the tumor's heterogeneity and requirement of the presence of squamoid…”
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Altered steady state and activity-dependent de novo protein expression in fragile X syndrome by Bowling, Heather, Bhattacharya, Aditi, Zhang, Guoan, Alam, Danyal, Lebowitz, Joseph Z., Bohm-Levine, Nathaniel, Lin, Derek, Singha, Priyangvada, Mamcarz, Maggie, Puckett, Rosemary, Zhou, Lili, Aryal, Sameer, Sharp, Kevin, Kirshenbaum, Kent, Berry-Kravis, Elizabeth, Neubert, Thomas A., Klann, Eric

“…Whether fragile X mental retardation protein (FMRP) target mRNAs and neuronal activity contributing to elevated basal neuronal protein synthesis in fragile X…”
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Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function by Longo, Francesco, Mancini, Maria, Ibraheem, Pierre L., Aryal, Sameer, Mesini, Caterina, Patel, Jyoti C., Penhos, Elena, Rahman, Nazia, Mamcarz, Maggie, Santini, Emanuela, Rice, Margaret E., Klann, Eric

“…Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) has been shown to activate the eIF2α kinase PERK to directly regulate translation…”
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Ancient Anxiety Pathways Influence Drosophila Defense Behaviors by Mohammad, Farhan, Aryal, Sameer, Ho, Joses, Stewart, James Charles, Norman, Nurul Ayuni, Tan, Teng Li, Eisaka, Agnese, Claridge-Chang, Adam

“…Anxiety helps us anticipate and assess potential danger in ambiguous situations [1–3]; however, the anxiety disorders are the most prevalent class of…”
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Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model by Aryal, Sameer, Bonanno, Kevin, Song, Bryan, Mani, D.R., Keshishian, Hasmik, Carr, Steven A., Sheng, Morgan, Dejanovic, Borislav

“…Synaptic dysfunction is implicated in the pathophysiology of schizophrenia (SCZ) and bipolar disorder (BP). We use quantitative mass spectrometry to carry out…”
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Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice by Longo, Francesco, Aryal, Sameer, Anastasiades, Paul G., Maltese, Marta, Baimel, Corey, Albanese, Federica, Tabor, Joanna, Zhu, Jeffrey D., Oliveira, Mauricio M., Gastaldo, Denise, Bagni, Claudia, Santini, Emanuela, Tritsch, Nicolas X., Carter, Adam G., Klann, Eric

“…Individuals with fragile X syndrome (FXS) are frequently diagnosed with autism spectrum disorder (ASD), including increased risk for restricted and repetitive…”
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Open surgery of complex long segment (giant) glomus spinal arteriovenous malformation by Deo, Alok, Aryal, Sameer, Sharma, Gopal Raman

“…Spinal arteriovenous malformation occurring in the pediatric population (under 15 years) initially complain of pain as the first symptom which is often over…”
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BRD3‐NUTM1‐expressing NUT carcinoma of lung on endobronchial ultrasound‐guided transbronchial needle aspiration cytology, a diagnostic pitfall by Aryal, Sameer Chhetri, Zia, Shereen, Rodgers, Shannon, Shen, Yulei, Perry, Kyle, Yuan, Lisi

“…Background Nuclear protein in testis (NUT) carcinoma (NC) is an aggressive type of poorly differentiated carcinoma with a variable degree of squamous…”
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Outcome of micro-lumbar discectomy and preventive measures to control discitis by Shrestha, Ram Chandra, Sharma, Gopal Raman, Bhattachan, Maya, Aryal, Sameer

“…Objective: The purpose of the present study is to describe the rate of post-operative discitis following micro-lumbar discectomy. Methods and Materials: This…”
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Cyto‐histo correlation and false‐negative urine: Before and after the Paris system for reporting urinary cytology by Yuan, Lisi, Gero, Margaret, Zia, Shereen, Aryal, Sameer Chhetri, Shetty, Sindhu, Reynolds, Jordan P.

“…Background The impact of implementing the Paris system (TPS) on the rate of discrepant cases in the negative for high‐grade urothelial carcinoma (NHGUC)…”
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Approach to native medical renal biopsy interpretation of glomerular disease by Aryal, Gopi, Aryal, Sameer Chhetri

“…Diverse pathogenetic mechanisms and clinical manifestation of renal diseases may produce the same renal morphologic pattern or variety of renal morphologic…”
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Early detection of cancer in Nepal: Role of liquid biopsy by Chhetri Aryal, Sameer, Aryal, Gopi

“…Cancers of the uterine cervix, breast, lung and stomach are four of the most common cancers in Nepal. Lack of knowledge and awareness about cancer, its risk…”
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Moving beyond P values: data analysis with estimation graphics by Ho, Joses, Tumkaya, Tayfun, Aryal, Sameer, Choi, Hyungwon, Claridge-Chang, Adam

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Role of Lumboperitoneal shunt in CSF diversion: Outcome in common indications and beyond by Aryal, Sameer

“…  Dr. Sameer Aryal1, Dr. Ramchandra Shrestha1, Dr. Alok Deo1, Dr. Gopal Raman Sharma1 1Dhirghayu Guru Hospital, Chabahil, Kathmandu Introduction: A…”
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Genetic removal of p70 S6K1 corrects coding sequence length-dependent alterations in mRNA translation in fragile X syndrome mice by Aryal, Sameer, Longo, Francesco, Klann, Eric

“…Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, but its…”
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Colloid cyst of third ventricle: Histopathological and ultrastructural study by Karki, Prasanna, Aryal, Sameer Chhetri, Aryal, Gopi, Panth, Rajesh, Bohara, Manoj, Joshi, Sumit, Paudel, Prakash, Shah, Damber Bikram, Sharma, Gopal Raman

“…Cysts occupying the third ventricle are rare lesions and may appear as an unusual cause of hydrocephalic crisis. A 40-year old woman with headache and one…”
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Immunohistoochemical evaluation of GATA-3, pAKT and Ki-67 in triple negative breast carcinoma by Aryal, Gopi, Chhetri Aryal, Sameer, Soejima, Yurie, Sheckler, Victoria, Eishi, Yoshinobu, Sawabe, Motoji

“…Background: Triple-negative breast cancers lack expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor -2. These…”
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Comparison of motor vehicle-involved e-scooter and bicycle crashes using standardized crash typology by Shah, Nitesh R., Aryal, Sameer, Wen, Yi, Cherry, Christopher R.

“…•We compare car-involved scooter crashes and bicycle crashes using standard typology.•Scooter-crashes and bicycle-crashes share many common features.•Most…”
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Gastric Glomus Tumor on EUS-FNA-Based Cytology; Clinicopathologic and Immuno-Histochemical Features of Four Cases Including a Case with Associated MIR143HG-NOTCH2 Fusion Gene by Aryal, Sameer Chhetri, Yuan, Lisi

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