Search Results - "Arvin, Matthew C"
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Photoactivatable drugs for nicotinic optopharmacology
Published in Nature methods (01-05-2018)“…Optopharmacological manipulation with ‘caged’ glutamate and GABA has enabled the study of these ligands’ cognate receptors, but other ligands such as tertiary…”
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Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission
Published in Cell reports (Cambridge) (22-05-2018)“…Ventral tegmental area (VTA) glutamate neurons are important components of reward circuitry, but whether they are subject to cholinergic modulation is unknown…”
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3
Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain
Published in PloS one (01-07-2017)“…Nicotinic acetylcholine receptors containing α4 subunits (α4β2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive action of…”
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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells
Published in Diabetologia (01-11-2023)“…Aims/hypothesis Increased circulating levels of incompletely processed insulin (i.e. proinsulin) are observed clinically in type 1 and type 2 diabetes…”
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Chronic Nicotine Exposure Alters the Neurophysiology of Habenulo-Interpeduncular Circuitry
Published in The Journal of neuroscience (29-05-2019)“…Antagonism of nicotinic acetylcholine receptors (nAChRs) in the medial habenula (MHb) or interpeduncular nucleus (IPN) triggers withdrawal-like behaviors in…”
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Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells
Published in Blood (20-07-2023)“…•Helper T-cell response to coagulation factor VIII critically depends on a select set of anatomically distinct antigen-presenting cells.•Innate immune…”
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Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
Published in Journal of visualized experiments (25-01-2019)“…Acetylcholine (ACh) acts through receptors to modulate a variety of neuronal processes, but it has been challenging to link ACh receptor function with…”
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8
Altered nicotine reward-associated behavior following [alpha]4 nAChR subunit deletion in ventral midbrain
Published in PloS one (31-07-2017)“…Nicotinic acetylcholine receptors containing [alpha]4 subunits ([alpha]4[beta]2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive…”
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