Factors associated with the presence of postoperative headache in elective surgery patients: a prospective single center cohort study

Factors associated with the presence of postoperative headache in elective surgery patients: a prospective single center cohort study

Purpose Headache is an important cause of minor postoperative morbidity. In this study we evaluated the association of anesthesia and surgery with the occurrence of postoperative headache in elective surgery patients. Methods After obtaining ethical approval, 446 patients were enrolled in this prosp...

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Bibliographic Details
Published in:Journal of anesthesia Vol. 31; no. 2; pp. 225 - 236
Main Authors: Matsota, Paraskevi K., Christodoulopoulou, Theodora C., Batistaki, Chrysanthi Z., Arvaniti, Chryssa C., Voumvourakis, Konstantinos I., Kostopanagiotou, Georgia G.
Format: Journal Article
Language:English
Published: Tokyo Springer Japan 01-04-2017
Springer
Subjects:
Adult
Analysis
Anesthesia
Anesthesia - adverse effects
Anesthesia - methods
Anesthesiology
Caffeine
Critical Care Medicine
Elective Surgical Procedures - adverse effects
Elective Surgical Procedures - methods
Emergency Medicine
Female
Headache
Headache - epidemiology
Hospital patients
Humans
Hypotension - etiology
Intensive
Male
Medicine
Medicine & Public Health
Methyl Ethers - administration & dosage
Middle Aged
Odds Ratio
Original Article
Pain Medicine
Postoperative Complications - epidemiology
Prospective Studies
Risk Factors
Analgesia
Anesthesia
Postoperative headache
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Summary:Purpose Headache is an important cause of minor postoperative morbidity. In this study we evaluated the association of anesthesia and surgery with the occurrence of postoperative headache in elective surgery patients. Methods After obtaining ethical approval, 446 patients were enrolled in this prospective, single-centre cohort study. Participants were interviewed preoperatively, and for five days postoperatively, regarding the appearance of headache, while demographics, lifestyle, type of anesthesia and surgery, the anesthetic drugs administered and intraoperative adverse effects were recorded. Multiple logistic regression analysis was conducted in order to identify independent factors associated with postoperative headache, both in the total sample and in patients without previous history of headache. Results The observed overall frequency of postoperative headache was 28.3% ( N  = 126) in the total sample. In patients with previous history of headache, the frequency of postoperative headache was 41% ( N  = 89), while in those with no history the frequency of postoperative headache was 16.2% ( N  = 37). Female gender [ p  = 0.024; odds ratio (OR) = 2.1], sevoflurane administration ( p  < 0.001; OR = 3.66), intraoperative hypotension ( p  = 0.008; OR = 2.12) and smoking ( p  = 0.006; OR = 1.74) were independently associated with postoperative headache. In patients without previous history, female gender ( p  = 0.005; OR = 4.77), sevoflurane administration ( p  = 0.001; OR = 6.9), intraoperative hypotension ( p  = 0.006; OR = 6.7) and caffeine consumption ( p  = 0.041; OR = 5.28) presented greater likelihood for postoperative headache, while smoking revealed no association. Conclusion Female gender, sevoflurane, smoking and intraoperative hypotension were documented as independent risk factors for postoperative headache. In patients with no previous history of headache, caffeine consumption was an additional independent factor for postoperative headache, while smoking revealed no association.
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ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-016-2285-z