Search Results - "Arun, J"
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Past, present and future perspectives in nonalcoholic fatty liver disease
Published in Nature reviews. Gastroenterology & hepatology (01-06-2019)“…Nonalcoholic fatty liver disease (NAFLD) was first described as a distinct clinical entity four decades ago. However, the condition has become the centre of…”
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Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease
Published in Gut (01-01-2017)“…Given the high prevalence and rising incidence of non-alcoholic fatty liver disease (NAFLD), the absence of approved therapies is striking. Although the…”
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Identification of plant leaf diseases using a nine-layer deep convolutional neural network
Published in Computers & electrical engineering (01-06-2019)“…•We proposed a 9-layer deep convolutional neural network for leaf disease identification.•We used six different types of image augmentation methods, and…”
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Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease
Published in Hepatology (Baltimore, Md.) (01-01-2018)“…Nonalcoholic fatty liver disease (NAFLD) and resulting nonalcoholic steatohepatitis (NASH) are highly prevalent in the United States, where they are a growing…”
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The global NAFLD epidemic
Published in Nature reviews. Gastroenterology & hepatology (01-11-2013)“…Global differences in the prevalence and presentation of NAFLD are presented in this Perspectives article. The authors also convey how scientific advances in…”
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Mechanisms of NAFLD development and therapeutic strategies
Published in Nature medicine (01-07-2018)“…There has been a rise in the prevalence of nonalcoholic fatty liver disease (NAFLD), paralleling a worldwide increase in diabetes and metabolic syndrome…”
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Toward More Accurate Nomenclature for Fatty Liver Diseases
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2019)Get full text
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Therapeutic pipeline in nonalcoholic steatohepatitis
Published in Nature reviews. Gastroenterology & hepatology (01-06-2021)“…Our understanding of nonalcoholic fatty liver disease pathophysiology continues to advance rapidly. Accordingly, the field has moved from describing the…”
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A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis
Published in The New England journal of medicine (25-03-2021)“…Patients with nonalcoholic steatohepatitis were randomly assigned to receive subcutaneous semaglutide or placebo. The incidence of NASH resolution was…”
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Therapies in non‐alcoholic steatohepatitis (NASH)
Published in Liver international (01-01-2017)“…The hallmark of non‐alcoholic fatty liver disease (NAFLD) is excessive fatty accumulation in the hepatocytes, which may be an isolated event (non‐alcoholic…”
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NASH: A global health problem
Published in Hepatology research (01-07-2011)“…Non‐alcoholic fatty liver disease (NAFLD) is a major public health problem both in the Western world and in the East. This is mainly due to the high prevalence…”
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From NAFLD to MAFLD: Implications of a Premature Change in Terminology
Published in Hepatology (Baltimore, Md.) (01-03-2021)“…Despite the substantial gains in our understanding of NAFLD/NASH over the past 2 decades, there has been some dissatisfaction with the terminology…”
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Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review
Published in Diabetes, obesity & metabolism (01-05-2021)“…Aims To conduct a systematic literature review to identify recent epidemiological, biomarker, genetic and clinical evidence that expands our understanding of…”
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Molecular Mechanisms of Lipotoxicity and Glucotoxicity in Nonalcoholic Fatty Liver Disease
Published in Metabolism, clinical and experimental (01-08-2016)“…Abstract The exposure of hepatocytes to high concentrations of lipids and carbohydrates and the ensuing hepatocellular injury are termed lipotoxicity and…”
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Preclinical models of non-alcoholic fatty liver disease
Published in Journal of hepatology (01-02-2018)“…Non-alcoholic fatty liver disease (NAFLD) can manifest as non-alcoholic fatty liver (NAFL) or non-alcoholic steatohepatitis (NASH). NASH is often associated…”
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Management of NAFLD: a stage-based approach
Published in Nature reviews. Gastroenterology & hepatology (01-04-2016)“…Key Points NAFLD is the most common cause of liver disease, affecting 30% of the US population; however, the goals of treatment differ based on stage of…”
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The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2012)Get full text
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Noninvasive Assessment of Liver Fibrosis in NAFLD
Published in Clinical gastroenterology and hepatology (01-07-2023)“…Nonalcoholic fatty liver disease (NAFLD) has emerged as a leading cause of liver-related morbidity and mortality worldwide, afflicting approximately a billion…”
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The Etiology of Hepatocellular Carcinoma and Consequences for Treatment
Published in The oncologist (Dayton, Ohio) (01-11-2010)“…Most patients with hepatocellular carcinoma (HCC) have liver cirrhosis, which develops following long periods of chronic liver disease. Cirrhosis is…”
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