Search Results - "Artusio, Fiora"

Surface-induced crystallization of pharmaceuticals and biopharmaceuticals: A review by Artusio, Fiora, Pisano, Roberto

“…[Display omitted] Despite the wide occurrence of crystallization in the pharmaceutical industry, deep understanding and fine control of the process remain a…”
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Polymeric nanocapsules via interfacial cationic photopolymerization in miniemulsion by Artusio, Fiora, Bazzano, Marco, Pisano, Roberto, Coulon, Pierre-Eugène, Rizza, Giancarlo, Schiller, Tara, Sangermano, Marco

“…The synthesis of polymeric nanocapsules by means of miniemulsion cationic polymerization has been investigated here. The core-shell structure was obtained by…”
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Advances in Pharmaceutical Crystals: Control over Nucleation and Polymorphism by Artusio, Fiora, Contreras-Montoya, Rafael, Gavira, José A

“…The Special Issue “Advances in Pharmaceutical Crystals: Control over Nucleation and Polymorphism” collects eight papers focusing on different aspects of…”
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Effect of Polymerization Time on the Binding Properties of Ciprofloxacin-Imprinted nanoMIPs Prepared by Solid-Phase Synthesis by Chiarello, Matteo, Anfossi, Laura, Cavalera, Simone, Di Nardo, Fabio, Artusio, Fiora, Pisano, Roberto, Baggiani, Claudio

“…An innovative approach to imprinted nanoparticles (nanoMIPs) is represented by solid-phase synthesis. Since the polymeric chains grow over time and rearrange…”
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Freeze-Drying of Pharmaceuticals in Vials Nested in a Rack System-Part I: Freezing Behaviour by Pisano, Roberto, Artusio, Fiora, Adami, Marco, Barresi, Antonello A, Fissore, Davide, Frare, Maria Chiara, Zanetti, Francesco, Zunino, Gabriele

“…The distribution of biopharmaceuticals often requires either ultra-cold conditions or lyophilisation. In both cases, the drug product is frozen and, thus,…”
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The Freeze-Drying of Pharmaceuticals in Vials Nested in a Rack System—Part II: Primary Drying Behaviour by Artusio, Fiora, Adami, Marco, Barresi, Antonello A, Fissore, Davide, Frare, Maria Chiara, Udrescu, Claudia I, Pisano, Roberto

“…The freeze-drying of biopharmaceuticals is a common strategy to extend their shelf-life and facilitate the distribution of therapeutics. The drying phase is…”
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Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form by Artusio, Fiora, Castellví, Albert, Pisano, Roberto, Gavira, José A.

“…Agarose gels provide the ideal environment for studying the nucleation step of complex biomacromolecules under diffusion-controlled conditions. In the present…”
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Shear stress as a driver of degradation for protein-based therapeutics: More accomplice than culprit by Moino, Camilla, Artusio, Fiora, Pisano, Roberto

“…Protein degradation is a major concern for protein-based therapeutics. It may alter the biological activity of the product and raise the potential for…”
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DSC reveals the excipient impact on aggregation propensity of pharmaceutical peptides during freezing by Zäh, Maximilian, Brandenbusch, Christoph, Artusio, Fiora, Sadowski, Gabriele, Pisano, Roberto

“…Pharmaceutical peptides are susceptible to aggregation in solution, making stabilization by addition of suitable excipients essential. To investigate this…”
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Role of Self-Assembled Surface Functionalization on Nucleation Kinetics and Oriented Crystallization of a Small-Molecule Drug: Batch and Thin-Film Growth of Aspirin as a Case Study by Artusio, Fiora, Fumagalli, Francesco, Valsesia, Andrea, Ceccone, Giacomo, Pisano, Roberto

“…The present paper assesses the heterogeneous nucleation of a small-molecule drug and its relationship with the surface chemistry of engineered heteronucleants…”
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Insights into Thermal Interactions in Frozen Pharmaceutical Vials: Effects on Ice Nucleation Times and Inhibition by Pisano, Roberto, Semeraro, Jessica, Artusio, Fiora, Barresi, Antonello A.

“…Purpose This study investigates the thermal interactions between adjacent vials during freezing and assesses their impact on nucleation times. Methods Various…”
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Self-Assembled Monolayers As a Tool to Investigate the Effect of Surface Chemistry on Protein Nucleation by Artusio, Fiora, Gavira, José A., Pisano, Roberto

“…Modified surfaces like siliconized glass are commonly used to support protein crystallization and facilitate obtaining crystals. Over the years, various…”
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Protein crystallisation in agarose gel, a cheap and versatile technique by Gavira, José A., Artusio, Fiora, Castellví, Albert, Pisano, Roberto

“…Abstract only…”
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Synthesis of high payload nanohydrogels for the ecapsulation of hydrophilic molecules via inverse miniemulsion polymerization: caffeine as a case study by Artusio, Fiora, Ferri, Ada, Gigante, Valeria, Massella, Daniele, Mazzarino, Italo, Sangermano, Marco, Barresi, Antonello, Pisano, Roberto

“…The association of an active principle with a nanocarrier is known to improve its stability and protect it from external factors. Nevertheless, loading of…”
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Agarose Gel as a Medium for Growing and Tailoring Protein Crystals by Artusio, Fiora, Castellví, Albert, Sacristán, Anabel, Pisano, Roberto, Gavira, José A

“…The nucleation inducing ability of agarose gels has been exploited to study the crystallization of proteins in diffusion-dominated environments. The crystal…”
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Chondroitin sulfate and caseinophosphopeptides doped polyurethane-based highly porous 3D scaffolds for tendon-to-bone regeneration by Bianchi, Eleonora, Ruggeri, Marco, Del Favero, Elena, Pisano, Roberto, Artusio, Fiora, Ricci, Caterina, Vigani, Barbara, Ferraretto, Anita, Boselli, Cinzia, Icaro Cornaglia, Antonia, Rossi, Silvia, Sandri, Giuseppina

“…[Display omitted] •Thermoplastic polyurethane highly porous scaffolds are characterized by tendon-like mechanical properties.•Caseinophosphopeptides and…”
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A crystal engineering approach for rational design of curcumin crystals for Pickering stabilization of emulsions by Del Duca, Giulia, Parisi, Emmanuele, Artusio, Fiora, Calì, Eleonora, Fraterrigo Garofalo, Silvia, Rosso, Chiara, Cauda, Valentina, Chierotti, Michele R., Simone, Elena

“…[Display omitted] •A novel anti-solvent precipitation method to produce submicron curcumin crystals was designed.•Contact angle measurements and emulsification…”
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Bacterial ligands as flexible and sensitive detectors in rapid tests for antibodies to SARS-CoV-2 by Cavalera, Simone, Di Nardo, Fabio, Chiarello, Matteo, Serra, Thea, Colitti, Barbara, Guiotto, Cristina, Fagioli, Franca, Cagnazzo, Celeste, Denina, Marco, Palazzo, Annagloria, Artusio, Fiora, Pisano, Roberto, Rosati, Sergio, Baggiani, Claudio, Anfossi, Laura

“…Lateral flow immunoassay (LFIA) is widely employed as point-of-care tests (POCT) for the diagnosis of infectious diseases. The accuracy of LFIA largely depends…”
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Lignin: A Sustainable Antiviral Coating Material by Boarino, Alice, Wang, Heyun, Olgiati, Francesca, Artusio, Fiora, Özkan, Melis, Bertella, Stefania, Razza, Nicolò, Cagno, Valeria, Luterbacher, Jeremy S., Klok, Harm-Anton, Stellacci, Francesco

“…Transmission of viruses through contact with contaminated surfaces is an important pathway for the spread of infections. Antiviral surface coatings are useful…”
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Broad-Spectrum Supramolecularly Reloadable Antimicrobial Coatings by Artusio, Fiora, Müller, Lukas, Razza, Nicolò, Cordeiro Filipe, Inês, Olgiati, Francesca, Richter, Łukasz, Civera, Edoardo, Özkan, Melis, Gasbarri, Matteo, Rinaldi, Louisa, Wang, Heyun, Garcìa, Esther, Schafer, Julie, Michot, Lise, Butot, Sophie, Baert, Leen, Zuber, Sophie, Halik, Marcus, Stellacci, Francesco

“…Antimicrobial surfaces limit the spread of infectious diseases. To date, there is no antimicrobial coating that has widespread use because of short-lived and…”
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