Search Results - "Artis, David"

Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut by Artis, David

“…Key Points Mucosal surfaces of mammals are exquisitely susceptible to colonization by pathogens and are populated by elaborate mucosal-associated lymphoid…”
Get full text

New Paradigms in Type 2 Immunity by Pulendran, Bali, Artis, David

“…Nearly half of the world's population harbors helminth infections or suffers from allergic disorders. A common feature of this population is the so-called…”
Get full text

Neuronal-immune system cross-talk in homeostasis by Veiga-Fernandes, Henrique, Artis, David

“…Interactions between immune and neuronal cells are pillars in tissue homeostasis Maintenance of mammalian tissue homeostasis and function requires coordinated…”
Get full text

Innate lymphoid cells in the initiation, regulation and resolution of inflammation by Sonnenberg, Gregory F, Artis, David

“…The role of innate lymphoid cells (ILCs) in immune homeostasis and disease is reviewed. A previously unappreciated cell type of the innate immune system,…”
Get full text

Commensal bacteria at the interface of host metabolism and the immune system by Brestoff, Jonathan R, Artis, David

“…The mammalian gastrointestinal tract, the site of digestion and nutrient absorption, harbors trillions of beneficial commensal microbes from all three domains…”
Get full text

Immune Regulation of Metabolic Homeostasis in Health and Disease by Brestoff, Jonathan R., Artis, David

“…Obesity is an increasingly prevalent disease worldwide. While genetic and environmental factors are known to regulate the development of obesity and associated…”
Get full text

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis by Klose, Christoph S N, Artis, David

“…In this Review, Klose and Artis focus on how group 2 ILC and group 3 ILC responses are regulated and how they interact with other immune and non-immune cells…”
Get full text

Neuronal regulation of innate lymphoid cell responses by Yano, Hiroshi, Artis, David

“…The immune system and the peripheral nervous system are distributed throughout the body and surveil vital organs utilizing various sensory mechanisms. Previous…”
Get full text

Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity by Klose, Christoph S. N., Artis, David

“…The multifaceted organization of the immune system involves not only patrolling lymphocytes that constantly monitor antigen-presenting cells in secondary…”
Get full text

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22 by Sonnenberg, Gregory F, Fouser, Lynette A, Artis, David

“…The maintenance of barrier function at exposed surfaces of the mammalian body is essential for limiting exposure to environmental stimuli, preventing systemic…”
Get full text

Intestinal bacteria and the regulation of immune cell homeostasis by Hill, David A, Artis, David

“…The human intestine is colonized by an estimated 100 trillion bacteria. Some of these bacteria are essential for normal physiology, whereas others have been…”
Get full text

Emerging concepts and future challenges in innate lymphoid cell biology by Tait Wojno, Elia D, Artis, David

“…Innate lymphoid cells (ILCs) are innate immune cells that are ubiquitously distributed in lymphoid and nonlymphoid tissues and enriched at mucosal and barrier…”
Get full text

IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactions by Monticelli, Laurel A., Osborne, Lisa C., Noti, Mario, Tran, Sara V., Zaiss, Dietmar M. W., Artis, David

“…The barrier surfaces of the skin, lung, and intestine are constantly exposed to environmental stimuli that can result in inflammation and tissue damage…”
Get full text

Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair by Zaiss, Dietmar M W, Gause, William C, Osborne, Lisa C, Artis, David

“…Type 2 inflammatory responses can be elicited by diverse stimuli, including toxins, venoms, allergens, and infectious agents, and play critical roles in…”
Get full text

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice by Bain, Calum C, Bravo-Blas, Alberto, Scott, Charlotte L, Gomez Perdiguero, Elisa, Geissmann, Frederic, Henri, Sandrine, Malissen, Bernard, Osborne, Lisa C, Artis, David, Mowat, Allan McI

“…Many tissue-resident macrophages are derived from embryonic precursors. Mowat and colleagues show that embryonic precursor cells seed gut tissues but at…”
Get full text

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut by Howitt, Michael R., Lavoie, Sydney, Michaud, Monia, Blum, Arthur M., Tran, Sara V., Weinstock, Joel V., Gallini, Carey Ann, Redding, Kevin, Margolskee, Robert F., Osborne, Lisa C., Artis, David, Garrett, Wendy S.

“…The intestinal epithelium forms an essential barrier between a host and its microbiota. Protozoa and helminths are members of the gut microbiota of mammals,…”
Get full text

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis by Noti, Mario, PhD, Kim, Brian S., MD, Siracusa, Mark C., PhD, Rak, Gregory D., VMD, PhD, Kubo, Masato, PhD, Moghaddam, Amin E., MD, Sattentau, Quentin A., PhD, Comeau, Michael R., BSc, Spergel, Jonathan M., MD, PhD, Artis, David, PhD

“…Background Exposure to food allergens through a disrupted skin barrier has been recognized as a potential factor in the increasing prevalence of food allergy…”
Get full text

The microbiota regulate neuronal function and fear extinction learning by Chu, Coco, Murdock, Mitchell H., Jing, Deqiang, Won, Tae Hyung, Chung, Hattie, Kressel, Adam M., Tsaava, Tea, Addorisio, Meghan E., Putzel, Gregory G., Zhou, Lei, Bessman, Nicholas J., Yang, Ruirong, Moriyama, Saya, Parkhurst, Christopher N., Li, Anfei, Meyer, Heidi C., Teng, Fei, Chavan, Sangeeta S., Tracey, Kevin J., Regev, Aviv, Schroeder, Frank C., Lee, Francis S., Liston, Conor, Artis, David

“…Multicellular organisms have co-evolved with complex consortia of viruses, bacteria, fungi and parasites, collectively referred to as the microbiota 1 . In…”
Get full text

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut by Sonnenberg, Gregory F., Monticelli, Laurel A., Elloso, M. Merle, Fouser, Lynette A., Artis, David

“…Fetal CD4+ lymphoid tissue inducer (LTi) cells play a critical role in the development of lymphoid tissues. Recent studies identified that LTi cells persist in…”
Get full text

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity by Brestoff, Jonathan R., Kim, Brian S., Saenz, Steven A., Stine, Rachel R., Monticelli, Laurel A., Sonnenberg, Gregory F., Thome, Joseph J., Farber, Donna L., Lutfy, Kabirullah, Seale, Patrick, Artis, David

“…Group 2 innate lymphoid cells are shown to have a critical role in energy homeostasis by producing methionine-enkephalin peptides in response to interleukin…”
Get full text