Search Results - "Artificial organs"

FDA Modernization Act 2.0 allows for alternatives to animal testing by Han, Jason J.

“…On December 29, 2022, President Biden signed into law the FDA Modernization Act 2.0. The bill essentially refutes the Federal Food, Drug, and Cosmetics Act of…”
Get full text

EMG‐Based Estimation of Limb Movement Using Deep Learning With Recurrent Convolutional Neural Networks by Xia, Peng, Hu, Jie, Peng, Yinghong

“…A novel model based on deep learning is proposed to estimate kinematic information for myoelectric control from multi‐channel electromyogram (EMG) signals. The…”
Get full text

Tacrolimus: 20 years of use in adult kidney transplantation. What we should know about its nephrotoxicity by Bentata, Yassamine

“…Tacrolimus (or FK506), a calcineurin inhibitor (CNI) introduced in field of transplantation in the 1990s, is the cornerstone of most immunosuppressive regimens…”
Get full text

Continuous renal replacement therapy with the addition of CytoSorb cartridge in critically ill patients with COVID‐19 plus acute kidney injury: A case‐series by Alharthy, Abdulrahman, Faqihi, Fahad, Memish, Ziad A., Balhamar, Abdullah, Nasim, Nasir, Shahzad, Ahmad, Tamim, Hani, Alqahtani, Saleh A., Brindley, Peter G., Karakitsos, Dimitrios

“…Our aim was to investigate continuous renal replacement therapy (CRRT) with CytoSorb cartridge for patients with life‐threatening COVID‐19 plus acute kidney…”
Get full text

Smart materials in cardiovascular implants: Shape memory alloys and shape memory polymers by Holman, Heather, Kavarana, Minoo Naozer, Rajab, Taufiek Konrad

“…Smart materials have intrinsic properties that change in a controlled fashion in response to external stimuli. Currently, the only smart materials with a…”
Get full text

3D‐Printed PCL/rGO Conductive Scaffolds for Peripheral Nerve Injury Repair by Vijayavenkataraman, Sanjairaj, Thaharah, Siti, Zhang, Shuo, Lu, Wen Feng, Fuh, Jerry Ying Hsi

“…The incidence of peripheral nerve injuries is on the rise and the current gold standard for treatment of such injuries is nerve autografting. Given the severe…”
Get full text

Progress and prospects of magnetic iron oxide nanoparticles in biomedical applications: A review by Elahi, Narges, Rizwan, Muhammad

“…Nanoscience has been considered as one of the most substantial research in modern science. The utilization of nanoparticle (NP) materials provides numerous…”
Get full text

Refractory out‐of‐hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: A meta‐analysis of randomized trials by Scquizzato, Tommaso, Bonaccorso, Alessandra, Swol, Justyna, Gamberini, Lorenzo, Scandroglio, Anna Mara, Landoni, Giovanni, Zangrillo, Alberto

“…Background In adults with refractory out‐of‐hospital cardiac arrest, when conventional cardiopulmonary resuscitation (CPR) alone does not achieve return of…”
Get full text

Graphene oxide incorporated polycaprolactone/chitosan/collagen electrospun scaffold: Enhanced osteogenic properties for bone tissue engineering by Aidun, Amir, Safaei Firoozabady, Alireza, Moharrami, Mohammad, Ahmadi, Ali, Haghighipour, Nooshin, Bonakdar, Shahin, Faghihi, Shahab

“…This in vitro study aimed to evaluate the physicochemical and biological activity of the polycaprolactone/chitosan/collagen scaffolds incorporated with 0, 0.5,…”
Get full text

Fluid Dynamics in the HeartMate 3: Influence of the Artificial Pulse Feature and Residual Cardiac Pulsation by Wiegmann, Lena, Thamsen, Bente, de Zélicourt, Diane, Granegger, Marcus, Boës, Stefan, Schmid Daners, Marianne, Meboldt, Mirko, Kurtcuoglu, Vartan

“…Ventricular assist devices (VADs), among which the HeartMate 3 (HM3) is the latest clinically approved representative, are often the therapy of choice for…”
Get full text

Recent advancement of decellularization extracellular matrix for tissue engineering and biomedical application by Yang, Jiamin, Dang, Hangyu, Xu, Yi

“…Background Decellularized extracellular matrixs (dECMs) derived from organs and tissues have emerged as a promising tool, as they encompass the characteristics…”
Get full text

Numerical Analysis of Blood Damage Potential of the HeartMate II and HeartWare HVAD Rotary Blood Pumps by Thamsen, Bente, Blümel, Bastian, Schaller, Jens, Paschereit, Christian O., Affeld, Klaus, Goubergrits, Leonid, Kertzscher, Ulrich

“…Implantable left ventricular assist devices (LVADs) became the therapy of choice in treating end‐stage heart failure. Although survival improved substantially…”
Get full text

The economic impact of machine perfusion technology in liver transplantation by Boteon, Yuri L., Hessheimer, Amelia J., Brüggenwirth, Isabel M. A., Boteon, Amanda P. C. S., Padilla, María, Meijer, Vincent E., Domínguez‐Gil, Beatriz, Porte, Robert J., Perera, M. Thamara P. R., Martins, Paulo N.

“…Introduction Several clinical studies have demonstrated the safety, feasibility, and efficacy of machine perfusion in liver transplantation, although its…”
Get full text

Decellularized scaffolds for tissue engineering: Current status and future perspective by Rajab, Taufiek Konrad, O’Malley, Thomas J., Tchantchaleishvili, Vakhtang

“…Based on Organ Procurement and Transplantation Network data as of December 2019, more than 113 000 patients require an organ transplantation, yet, over the…”
Get full text

Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass by Squiccimarro, Enrico, Stasi, Alessandra, Lorusso, Roberto, Paparella, Domenico

“…Background Data from large cardiac surgery registries have been depicting a downward trend of mortality and morbidities in the last 20 years. However, despite…”
Get full text

Outcomes after extracorporeal membrane oxygenation support in COVID‐19 and non‐COVID‐19 patients by Kurihara, Chitaru, Manerikar, Adwaiy, Gao, Catherine Aiyuan, Watanabe, Satoshi, Kandula, Viswajit, Klonis, Alexandra, Hoppner, Vanessa, Karim, Azad, Saine, Mark, Odell, David D., Lung, Kalvin, Garza‐Castillon, Rafael, Kim, Samuel S., Walter, James McCauley, Wunderink, Richard G., Budinger, G. R. Scott, Bharat, Ankit

“…Background Veno‐venous extracorporeal membrane oxygenation (V‐V ECMO) support is increasingly used in the management of COVID‐19‐related acute respiratory…”
Get full text

Efficacy of Distal Perfusion Cannulae in Preventing Limb Ischemia During Extracorporeal Membrane Oxygenation: A Systematic Review and Meta‐Analysis by Juo, Yen‐Yi, Skancke, Matthew, Sanaiha, Yas, Mantha, Aditya, Jimenez, Juan C., Benharash, Peyman

“…To date, no consensus exists regarding indication, technique, or efficacy of distal perfusion cannulae (DPC) in preventing limb ischemia among patients…”
Get full text

Risk factors and outcomes for patients with bleeding complications receiving extracorporeal membrane oxygenation: An analysis of the Chinese Extracorporeal Life Support Registry by Li, Chenglong, Cai, Tong, Xie, Haixiu, Wang, Liangshan, Yang, Feng, Du, Zhongtao, Hong, Xiaoyang, Zhou, Chengbing, Li, Yimin, Qiu, Haibo, Tong, Zhaohui, Zeng, Hui, Peng, Zhiyong, Li, Xin, Hou, Xiaotong

“…Objective Bleeding is a severe complication of patients supported with extracorporeal membrane oxygenation (ECMO). This study aimed to analyze the occurrence,…”
Get full text

Venovenous Extracorporeal Membrane Oxygenation With Prophylactic Subcutaneous Anticoagulation Only: An Observational Study in More Than 60 Patients by Krueger, Kirsten, Schmutz, Axel, Zieger, Barbara, Kalbhenn, Johannes

“…Extracorporeal lung support and therapeutic anticoagulation are dogmatically linked for most clinicians in fear of clotting of the extracorporeal circuit. In…”
Get full text

Blood Purification With CytoSorb in Critically Ill Patients: Single‐Center Preliminary Experience by Calabrò, Maria Grazia, Febres, Daniela, Recca, Gaia, Lembo, Rosalba, Fominskiy, Evgeny, Scandroglio, Anna Mara, Zangrillo, Alberto, Pappalardo, Federico

“…The CytoSorb adsorber, a blood purification therapy, is able to remove molecules in the 5–60 kDa range which comprises the majority of inflammatory mediators…”
Get full text