Search Results - "Artiach, G"

The resolvin D1 receptor GPR32 transduces inflammation-resolution and atheroprotection by Arnardottir, H., Thul, S., Karadimou, G., Pawelzik, S.-C., Artiach, G., Mysdotter, V., Carracedo, M., Tarnawski, L., Caravaca, A.S., Baumgartner, R., Ketelhuth, D.F., Olofsson, P.S., Paulsson-Berne, G., Hansson, G.K., Back, M.

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Adipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer’s disease by Pedrós, I, Petrov, D, Artiach, G, Abad, S, Ramon-Duaso, C, Sureda, F, Pallàs, M, Beas-Zarate, C, Folch, J, Camins, Antoni

“…A growing body of evidence suggests that β-amyloid peptides (Aβ) are unlikely to be the only factor involved in Alzheimer’s disease (AD) aetiology. In fact, a…”
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The resolution of inflammation through omega-3 fatty acids in atherosclerosis, intimal hyperplasia, and vascular calcification by Carracedo, Miguel, Artiach, Gonzalo, Arnardottir, Hildur, Bäck, Magnus

“…Omega-3 fatty acids serve as the substrate for the formation of a group of lipid mediators that mediate the resolution of inflammation. The cardiovascular…”
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Omega-3 Polyunsaturated Fatty Acids Decrease Aortic Valve Disease Through the Resolvin E1 and ChemR23 Axis by Artiach, Gonzalo, Carracedo, Miguel, Plunde, Oscar, Wheelock, Craig E., Thul, Silke, Sjövall, Peter, Franco-Cereceda, Anders, Laguna-Fernandez, Andres, Arnardottir, Hildur, Bäck, Magnus

“…BACKGROUND:Aortic valve stenosis (AVS), which is the most common valvular heart disease, causes a progressive narrowing of the aortic valve as a consequence of…”
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The resolvin D1 receptor GPR32 transduces inflammation resolution and atheroprotection by Arnardottir, Hildur, Thul, Silke, Pawelzik, Sven-Christian, Karadimou, Glykeria, Artiach, Gonzalo, Gallina, Alessandro L, Mysdotter, Victoria, Carracedo, Miguel, Tarnawski, Laura, Caravaca, April S, Baumgartner, Roland, Ketelhuth, Daniel Fj, Olofsson, Peder S, Paulsson-Berne, Gabrielle, Hansson, Göran K, Bäck, Magnus

“…Chronic inflammation is a hallmark of atherosclerosis and results from an imbalance between proinflammatory and proresolving signaling. The human GPR32…”
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ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages by Laguna-Fernandez, Andres, Checa, Antonio, Carracedo, Miguel, Artiach, Gonzalo, Petri, Marcelo H, Baumgartner, Roland, Forteza, Maria J, Jiang, Xintong, Andonova, Teodora, Walker, Mary E, Dalli, Jesmond, Arnardottir, Hildur, Gisterå, Anton, Thul, Silke, Wheelock, Craig E, Paulsson-Berne, Gabrielle, Ketelhuth, Daniel F.J, Hansson, Göran K, Bäck, Magnus

“…BACKGROUND:In addition to enhanced proinflammatory signaling, impaired resolution of vascular inflammation plays a key role in atherosclerosis. Proresolving…”
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Dose-Dependent Risk Reduction for Myocardial Infarction with Eicosapentaenoic Acid: a Meta-analysis and Meta-regression Including the STRENGTH Trial by Sarajlic, Philip, Artiach, Gonzalo, Larsson, Susanna C., Bäck, Magnus

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The G-protein coupled receptor ChemR23 determines smooth muscle cell phenotypic switching to enhance high phosphate-induced vascular calcification by Carracedo, Miguel, Artiach, Gonzalo, Witasp, Anna, Clària, Joan, Carlström, Mattias, Laguna-Fernandez, Andres, Stenvinkel, Peter, Bäck, Magnus

“…Abstract Aims Vascular calcification, a marker of increased cardiovascular risk, is an active process orchestrated by smooth muscle cells. Observational…”
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High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents by Petrov, Dmitry, Pedrós, Ignacio, Artiach, Gonzalo, Sureda, Francesc X., Barroso, Emma, Pallàs, Mercè, Casadesús, Gemma, Beas-Zarate, Carlos, Carro, Eva, Ferrer, Isidro, Vazquez-Carrera, Manuel, Folch, Jaume, Camins, Antoni

“…Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted in an enormous strain on healthcare systems worldwide. The…”
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Stimulating the Resolution of Inflammation Through Omega-3 Polyunsaturated Fatty Acids in COVID-19: Rationale for the COVID-Omega-F Trial by Arnardottir, Hildur, Pawelzik, Sven-Christian, Öhlund Wistbacka, Ulf, Artiach, Gonzalo, Hofmann, Robin, Reinholdsson, Ingalill, Braunschweig, Frieder, Tornvall, Per, Religa, Dorota, Bäck, Magnus

“…Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 triggers an immune response…”
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Inflammation and its resolution in coronary artery disease: a tightrope walk between omega-6 and omega-3 polyunsaturated fatty acids by Artiach, Gonzalo, Sarajlic, Philip, Bäck, Magnus

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The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis by Carracedo, Miguel, Pawelzik, Sven‐Christian, Artiach, Gonzalo, Pouwer, Marianne G., Plunde, Oscar, Saliba‐Gustafsson, Peter, Ehrenborg, Ewa, Eriksson, Per, Pieterman, Elsbet, Stenke, Leif, Princen, Hans M. G., Franco‐Cereceda, Anders, Bäck, Magnus

“…Background and Purpose Tyrosine kinase inhibitors (TKI) used to treat chronic myeloid leukaemia (CML) have been associated with cardiovascular side effects,…”
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Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells by Carracedo, Miguel, Persson, Oscar, Saliba-Gustafsson, Peter, Artiach, Gonzalo, Ehrenborg, Ewa, Eriksson, Per, Franco-Cereceda, Anders, Bäck, Magnus

“…Autophagy serves as a cell survival mechanism which becomes dysregulated under pathological conditions and aging. Aortic valve thickening and calcification…”
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Omega-3 Polyunsaturated Fatty Acids and the Resolution of Inflammation: Novel Therapeutic Opportunities for Aortic Valve Stenosis? by Artiach, Gonzalo, Bäck, Magnus

“…Inflammation is well-established in cardiovascular disease, including valvular heart disease. Inflammation is a key process in the fibrosis and calcification…”
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Opposing Effects on Vascular Smooth Muscle Cell Proliferation and Macrophage-induced Inflammation Reveal a Protective Role for the Proresolving Lipid Mediator Receptor ChemR23 in Intimal Hyperplasia by Artiach, Gonzalo, Carracedo, Miguel, Clària, Joan, Laguna-Fernandez, Andres, Bäck, Magnus

“…Intimal hyperplasia remains a significant clinical problem in for example coronary artery bypass graft failure. Since omega-3 fatty acids reduce intimal…”
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Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification by Artiach, Gonzalo, Carracedo, Miguel, Seime, Till, Plunde, Oscar, Laguna-Fernandez, Andres, Matic, Ljubica, Franco-Cereceda, Anders, Bäck, Magnus

“…Aortic valve stenosis (AVS), a consequence of increased fibrosis and calcification of the aortic valve leaflets, causes progressive narrowing of the aortic…”
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FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification by Plunde, Oscar, Larsson, Susanna C., Artiach, Gonzalo, Thanassoulis, George, Carracedo, Miguel, Franco-Cereceda, Anders, Eriksson, Per, Bäck, Magnus

“…- Aortic stenosis (AS) contributes to cardiovascular mortality and morbidity but disease mechanisms remain largely unknown. Recent evidence associates a single…”
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Clonal occurrence of the Hutchinson-Gilford progeria syndrome lamin A mutation in chronic kidney disease by Revechon, G, Helgadottir, H, Viceconte, N, Witasp, A, Carvajal, AS, Whisenant, D, McGuinness, D, Artiach, G, Arzt, EW, Thorell, A, Babler, A, Ziegler, S, Kramann, R, Back, M, Shiels, PG, Wernerson, A, Stenvinkel, P, Eriksson, M

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Five-year incidence of chronic kidney disease (stage 3-5) and associated risk factors in a Spanish cohort: the MADIABETES Study by Salinero-Fort, Miguel A, San Andrés-Rebollo, Francisco J, Carmen de Burgos-Lunar, Gómez-Campelo, Paloma, Chico-Moraleja, Rosa M, López de Andrés, Ana, Jiménez-García, Rodrigo, Group, MADIABETES

“…To evaluate the incidence rate of Chronic Kidney Disease (CKD) stage 3-5 (persistent decreased kidney function under 60 mL/min per 1.73 m2) among patients with…”
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Castleman's disease by Alonso, M, Artiach, G, Fernández, A, Luna, P

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