Search Results - "Arthur, M. A."

Diagnosis, management and therapeutic strategies for congenital long QT syndrome by Wilde, Arthur A M, Amin, Ahmad S, Postema, Pieter G

“…Congenital long QT syndrome (LQTS) is characterised by heart rate corrected QT interval prolongation and life-threatening arrhythmias, leading to syncope and…”
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Inherited cardiac arrhythmias by Schwartz, Peter J., Ackerman, Michael J., Antzelevitch, Charles, Bezzina, Connie R., Borggrefe, Martin, Cuneo, Bettina F., Wilde, Arthur A. M.

“…The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome, catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome…”
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Brugada Syndrome by Mizusawa, Yuka, Wilde, Arthur A.M

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Impact of Genetics on the Clinical Management of Channelopathies by Schwartz, Peter J., MD, Ackerman, Michael J., MD, PhD, George, Alfred L., MD, Wilde, Arthur A.M., MD, PhD

“…There are few areas in cardiology in which the impact of genetics and genetic testing on clinical management has been as great as in cardiac channelopathies,…”
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Epidemiology of inherited arrhythmias by Offerhaus, Joost A., Bezzina, Connie R., Wilde, Arthur A. M.

“…The primary electrical disorders are a group of inherited cardiac ventricular arrhythmias that are a major cause of sudden cardiac death in young individuals…”
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Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice by Rossin, Raffaella, Versteegen, Ron M., Wu, Jeremy, Khasanov, Alisher, Wessels, Hans J., Steenbergen, Erik J., ten Hoeve, Wolter, Janssen, Henk M., van Onzen, Arthur H. A. M., Hudson, Peter J., Robillard, Marc S.

“…Current antibody-drug conjugates (ADCs) target internalising receptors on cancer cells leading to intracellular drug release. Typically, only a subset of…”
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Brugada syndrome and reduced right ventricular outflow tract conduction reserve: a final common pathway? by Behr, Elijah R, Ben-Haim, Yael, Ackerman, Michael J, Krahn, Andrew D, Wilde, Arthur A M

“…Abstract Brugada syndrome (BrS) was first described as a primary electrical disorder predisposing to the risk of sudden cardiac death and characterized by…”
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Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers: A European Cohort Study by VAN RIJSINGEN, Ingrid A. W, ARBUSTINI, Eloisa, JENKINS, Sharon, ROWLAND, Camilla, ASLAM, Uzma, WILDE, Arthur A. M, PERROT, Andreas, PANKUWEIT, Sabine, ZWINDERMAN, Aeilko H, CHARRON, Philippe, PINTO, Yigal M, ELLIOTT, Perry M, MOGENSEN, Jens, HERMANS-VAN AST, Johanna F, VAN DER KOOI, Anneke J, VAN TINTELEN, J. Peter, VAN DEN BERG, Maarten P, PILOTTO, Andrea, PASOTTI, Michele

“…The purpose of this study was to determine risk factors that predict malignant ventricular arrhythmias (MVA) in Lamin A/C (LMNA) mutation carriers. LMNA…”
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Genetic testing for inherited cardiac disease by Wilde, Arthur A. M., Behr, Elijah R.

“…Cardiomyopathies and cardiac channelopathies can predispose individuals to sudden cardiac death. The genetics that underlie these phenotypes are complex and…”
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Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel by Wilde, Arthur A.M, Brugada, Ramon

“…Variations in the gene encoding for the major sodium channel (Nav1.5) in the heart, SCN5A, has been shown to cause a number of arrhythmia syndromes (with or…”
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Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death by Walsh, Roddy, Adler, Arnon, Amin, Ahmad S, Abiusi, Emanuela, Care, Melanie, Bikker, Hennie, Amenta, Simona, Feilotter, Harriet, Nannenberg, Eline A, Mazzarotto, Francesco, Trevisan, Valentina, Garcia, John, Hershberger, Ray E, Perez, Marco V, Sturm, Amy C, Ware, James S, Zareba, Wojciech, Novelli, Valeria, Wilde, Arthur A M, Gollob, Michael H

“…Abstract Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) and short QT syndrome (SQTS) are inherited arrhythmogenic disorders that can cause…”
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Sudden cardiac death in the young: the molecular autopsy and a practical approach to surviving relatives by Semsarian, Christopher, Ingles, Jodie, Wilde, Arthur A M

“…The sudden death of a young, apparently fit and healthy person is amongst the most challenging scenarios in clinical medicine. Sudden cardiac death (SCD) is a…”
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Increasing Red Maple Leaf Litter Alters Decomposition Rates and Nitrogen Cycling in Historically Oak-Dominated Forests of the Eastern U.S by Alexander, H. D, Arthur, M. A

“…Without canopy-opening fire disturbances, shade-tolerant, fire-sensitive species like red maple (Acer rubrum L.) proliferate in many historically oak-dominated…”
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Risk stratification of sudden cardiac death: a review by Tfelt-Hansen, Jacob, Garcia, Rodrigue, Albert, Christine, Merino, Jose, Krahn, Andrew, Marijon, Eloi, Basso, Cristina, Wilde, Arthur A M, Haugaa, Kristina Hermann

“…Abstract Sudden cardiac death (SCD) is responsible for several millions of deaths every year and remains a major health problem. To reduce this burden,…”
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Permanent Leadless Cardiac Pacing: Results of the LEADLESS Trial by Reddy, Vivek Y, Knops, Reinoud E, Sperzel, Johannes, Miller, Marc A, Petru, Jan, Simon, Jaroslav, Sediva, Lucie, de Groot, Joris R, Tjong, Fleur V.Y, Jacobson, Peter, Ostrosff, Alan, Dukkipati, Srinivas R, Koruth, Jacob S, Wilde, Arthur A.M, Kautzner, Josef, Neuzil, Petr

“…BACKGROUND—Conventional cardiac pacemakers are associated with several potential short- and long-term complications related to either the transvenous lead or…”
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Genetic and Clinical Advances in Congenital Long QT Syndrome by Mizusawa, Yuka, Horie, Minoru, Wilde, Arthur AM

“…Congenital long QT syndrome (LQTS) is an inherited arrhythmia syndrome characterized by a prolonged QT interval on the 12-lead ECG, torsades de pointes and a…”
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A Mutation in CALM1 Encoding Calmodulin in Familial Idiopathic Ventricular Fibrillation in Childhood and Adolescence by Marsman, Roos F., MD, Barc, Julien, PhD, Beekman, Leander, BSc, Alders, Marielle, PhD, Dooijes, Dennis, PhD, van den Wijngaard, Arthur, PhD, Ratbi, Ilham, MD, Sefiani, Abdelaziz, MD, PhD, Bhuiyan, Zahurul A., MD, PhD, Wilde, Arthur A.M., MD, PhD, Bezzina, Connie R., PhD

“…Objectives This study aimed to identify the genetic defect in a family with idiopathic ventricular fibrillation (IVF) manifesting in childhood and adolescence…”
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Flecainide Therapy Reduces Exercise-Induced Ventricular Arrhythmias in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia by van der Werf, Christian, MD, Kannankeril, Prince J., MD, MSCI, Sacher, Frederic, MD, Krahn, Andrew D., MD, Viskin, Sami, MD, Leenhardt, Antoine, MD, Shimizu, Wataru, MD, PhD, Sumitomo, Naokata, MD, Fish, Frank A., MD, Bhuiyan, Zahurul A., MD, PhD, Willems, Albert R., MD, PhD, van der Veen, Maurits J., MD, PhD, Watanabe, Hiroshi, MD, PhD, Laborderie, Julien, MD, Haïssaguerre, Michel, MD, Knollmann, Björn C., MD, PhD, Wilde, Arthur A.M., MD, PhD

“…Objectives This study evaluated the efficacy and safety of flecainide in addition to conventional drug therapy in patients with catecholaminergic polymorphic…”
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Bioorthogonal Tetrazine Carbamate Cleavage by Highly Reactive trans-Cyclooctene by van Onzen, Arthur H. A. M, Versteegen, Ron M, Hoeben, Freek J. M, Filot, Ivo A. W, Rossin, Raffaella, Zhu, Tong, Wu, Jeremy, Hudson, Peter J, Janssen, Henk M, ten Hoeve, Wolter, Robillard, Marc S

“…The high rate of the ‘click-to-release’ reaction between an allylic substituted trans-cyclooctene linker and a tetrazine activator has enabled exceptional…”
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Prediction of ventricular arrhythmia in phospholamban p.Arg14del mutation carriers–reaching the frontiers of individual risk prediction by Verstraelen, Tom E, van Lint, Freyja H M, Bosman, Laurens P, de Brouwer, Remco, Proost, Virginnio M, Abeln, Bob G S, Taha, Karim, Zwinderman, Aeilko H, Dickhoff, Cathelijne, Oomen, Toon, Schoonderwoerd, Bas A, Kimman, Gerardus P, Houweling, Arjan C, Gimeno-Blanes, Juan R, Asselbergs, Folkert W, van der Zwaag, Paul A, de Boer, Rudolf A, van den Berg, Maarten P, van Tintelen, J Peter, Wilde, Arthur A M

“…Abstract Aims This study aims to improve risk stratification for primary prevention implantable cardioverter defibrillator (ICD) implantation by developing a…”
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