Search Results - "Arthaud, Charles Antoine"
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Platelet depletion limits the severity but does not prevent the occurrence of experimental transfusion‐related acute lung injury
Published in Transfusion (Philadelphia, Pa.) (01-04-2020)“…BACKGROUND Transfusion‐related acute lung injury (TRALI) is a severe pulmonary reaction due to blood transfusions. The pathophysiology of this complication is…”
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Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury
Published in Scientific reports (29-08-2019)“…Platelet transfusions can cause adverse reactions in their recipients, including transfusion-related acute lung injury (TRALI). The pathophysiology of TRALI…”
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Inhibition of the CD40/CD40L complex protects mice against ALI‐induced pancreas degradation
Published in Transfusion (Philadelphia, Pa.) (01-03-2019)“…BACKGROUND Acute lung injury (ALI) is a severe complication of transfusion. In a previous study, we saw that inhibition of the CD40/CD40L complex allowed…”
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In platelet single donor apheresis, platelet factor 4 levels correlated with donor’s age and decreased during storage
Published in Scientific reports (14-03-2024)“…The human population is ageing worldwide. The World Health Organization estimated that the world’s population of people aged 60 years and older will increase…”
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Soluble CD40L and CD62P levels differ in single‐donor apheresis platelet concentrates and buffy coat–derived pooled platelet concentrates
Published in Transfusion (Philadelphia, Pa.) (01-01-2019)“…BACKGROUND Platelet storage lesions are structural and biochemical changes in platelet concentrates (PCs), and depend on variables in collection and…”
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Platelet concentrate supernatants alter endothelial cell mRNA and protein expression patterns as a function of storage length
Published in Transfusion (Philadelphia, Pa.) (01-11-2018)“…BACKGROUND Platelet transfusions are safe but can nevertheless cause serious adverse reactions (SARs). This study investigated the effects of platelet…”
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Platelet components associated with adverse reactions: predictive value of mitochondrial DNA relative to biological response modifiers
Published in Transfusion (Philadelphia, Pa.) (01-02-2016)“…BACKGROUND Biological response modifiers (BRMs), secreted by platelets (PLTs) during storage, play a role in adverse events (AEs) associated with transfusion…”
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Immune-reactive soluble OX40 ligand, soluble CD40 ligand, and interleukin-27 are simultaneously oversecreted in platelet components associated with acute transfusion reactions
Published in Transfusion (Philadelphia, Pa.) (01-03-2014)“…Background Leukoreduction of labile blood components dramatically decreases the frequency of minor, intermediate, and severe adverse events (AEs), referred to…”
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Bioactive lipids as biomarkers of adverse reactions associated with apheresis platelet concentrate transfusion
Published in Frontiers in immunology (17-04-2023)“…Platelet concentrate (PC) transfusion seeks to provide haemostasis in patients presenting severe central thrombocytopenia or severe bleeding. PCs may induce…”
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Modeling the effect of platelet concentrate supernatants on endothelial cells: focus on endocan/ESM‐1
Published in Transfusion (Philadelphia, Pa.) (01-02-2018)“…BACKGROUND Platelets (PLTs) are prone to activation and the release of biologic response modifiers (BRMs) under storage conditions. The transfusion…”
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Role of Siglec-7 in apoptosis in human platelets
Published in PloS one (17-09-2014)“…Platelets participate in tissue repair and innate immune responses. Sialic acid-binding immunoglobulin-like lectins (Siglecs) are well-characterized I-type…”
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Inflammatory profile of convalescent plasma to treat COVID: Impact of amotosalen/UVA pathogen reduction technology
Published in Frontiers in immunology (07-10-2022)“…Blood products in therapeutic transfusion are now commonly acknowledged to contain biologically active constituents during the processes of preparation. In the…”
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The efficacy of therapeutic plasma exchange in COVID-19 patients on endothelial tightness in vitro is hindered by platelet activation
Published in Frontiers in cardiovascular medicine (04-05-2023)“…Coronavirus disease (COVID)-19 is characterised in particular by vascular inflammation with platelet activation and endothelial dysfunction. During the…”
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Platelets as Key Factors in Inflammation: Focus on CD40L/CD40
Published in Frontiers in immunology (03-02-2022)“…Platelets are anucleate cytoplasmic fragments derived from the fragmentation of medullary megakaryocytes. Activated platelets adhere to the damaged endothelium…”
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Similar effect of co-administration of methotrexate and folic acid for the treatment of arthritis compared to separate administration
Published in Rheumatology (03-04-2023)“…Abstract Objectives MTX is the recommended first-line treatment for RA associated with folic acid (FA) to reduce side effects related to MTX. Here, we proposed…”
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Human platelets can discriminate between various bacterial LPS isoforms via TLR4 signaling and differential cytokine secretion
Published in Clinical immunology (Orlando, Fla.) (01-12-2012)“…Abstract Platelets are currently acknowledged as cells of innate immunity and inflammation and play a complex role in sepsis. We examined whether different…”
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Lipidomic analysis of differently prepared platelet concentrates in additive solution during storage
Published in Blood transfusion = Trasfusione del sangue (01-09-2023)“…Background: Structural and biochemical changes in stored platelets are influenced by collection and processing methods. Lesions may appear during platelet…”
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LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand
Published in BMC immunology (31-01-2015)“…Platelets are instrumental to primary haemostasis; in addition, as they are central to endothelium vascular repair, they play a role in physiological…”
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NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets
Published in Frontiers in immunology (06-02-2017)“…The primary toll-like receptor (TLR)-mediated immune cell response pathway common for all TLRs is MyD88-dependent activation of NF-κB, a seminal transcription…”
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Assessment of soluble platelet CD40L and CD62P during the preparation process and the storage of apheresis platelet concentrates: Absence of factors related to donors and donations
Published in Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine (01-09-2018)“…Platelet transfusions may be associated with certain adverse effects in recipients, potentially caused by the presence of biological response modifiers…”
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