Search Results - "Arsova, Angela"
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Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants
Published in Scientific reports (11-09-2015)“…The metabotropic glutamate receptors have a wide range of modulatory functions in the central nervous system. They are among the most highly pursued drug…”
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Detailed In Vitro Pharmacological Characterization of Clinically Tested Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
Published in Molecular pharmacology (01-07-2020)“…Negative allosteric modulation of the metabotropic glutamate 5 (mGlu ) receptor has emerged as a potential strategy for the treatment of neurologic disorders…”
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CXCR4-Specific Nanobodies as Potential Therapeutics for WHIM syndrome
Published in The Journal of pharmacology and experimental therapeutics (01-10-2017)“…WHIM syndrome is a rare congenital immunodeficiency disease, named after its main clinical manifestations: warts, hypogammaglobulinemia, infections, and…”
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Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 as Tool Compounds to Study Signaling Bias
Published in Molecular pharmacology (01-05-2021)“…Positive allosteric modulation of metabotropic glutamate subtype 5 (mGlu ) receptor has emerged as a potential new therapeutic strategy for the treatment of…”
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