Search Results - "Arshad, Shumaila"
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Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems
Published in Polymers (30-05-2020)“…As less reactive s-protected thiomers can likely interpenetrate the mucus gel layer to a higher extent before getting immobilized via disulfide bond formation…”
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Safety and Pharmaceutical Evaluation of a Novel Natural Polymer, Ocicum, as Solubility and Dissolution Enhancer in Solid Dispersion
Published in Pharmaceuticals (Basel, Switzerland) (14-07-2022)“…Plant mucilages are commonly employed as excipients in pharmaceutical manufacturing. Ocimum basilicum (Lamiaceae family), a source of hydrophilic mucilage…”
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3
Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery
Published in International journal of pharmaceutics (15-04-2021)“…[Display omitted] •Thiolated β-CD was synthesized by replacing primary –OH groups with thiol groups.•Thiolated β-CD showed no inflammation on ocular mucosa…”
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4
Transforming cancer treatment: The potential of nanonutraceuticals
Published in International journal of pharmaceutics (25-12-2024)“…[Display omitted] Chemotherapy in the management of cancer is constrained by limitations like off-target effects, poor bioavailability, and dose-dependent…”
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Microwave-assisted, sulfhydryl-modified β-cyclodextrin-silymarin inclusion complex: A diverse approach to improve oral drug bioavailability via enhanced mucoadhesion and permeation
Published in Carbohydrate polymers (15-01-2025)“…The current study aimed to generate a sulfhydryl-modified β-cyclodextrin-silymarin complex (sulfhydryl-modified β-CD-SMN complex) and to evaluate the…”
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6
Correlation of body mass index, with cardiometabolic and cardiorespiratory fitness in health care professionals of Multan
Published in Journal of the Pakistan Medical Association (31-10-2024)“…The current study was conducted at Ali-Ul-Murtaza Department of Rehabilitation Sciences, Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan,…”
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7
Zeta potential changing self-nanoemulsifying drug delivery systems: A newfangled approach for enhancing oral bioavailability of poorly soluble drugs
Published in International journal of pharmaceutics (25-04-2024)“…[Display omitted] The mucus is a defensive barrier for different drug-loaded systems. To overcome this obstacle, the crucial factor is the surface charge. Due…”
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S-Protected thiolated nanostructured lipid carriers exhibiting improved mucoadhesive properties
Published in International journal of pharmaceutics (25-09-2020)“…[Display omitted] •S-protected thiolated fatty acid conjugate was synthesized by amide bond formation.•Drug loaded NLCs were prepared by nano-template…”
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Pioglitazone-loaded nanostructured lipid carriers: In-vitro and in-vivo evaluation for improved bioavailability
Published in Journal of drug delivery science and technology (01-01-2023)“…Pioglitazone (PZ), a highly lipophilic Class II drug with poor aqueous solubility possesses low oral bioavailability. The oral bioavailability of pioglitazone…”
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10
Mucoadhesive, Fluconazole-Loaded Nanogels Complexed with Sulfhydryl-β-cyclodextrin for Oral Thrush Treatment
Published in AAPS PharmSciTech (26-09-2023)“…The objective of this study was to generate fluconazole-loaded mucoadhesive nanogels to address the problem of hydrophobicity of fluconazole (FL). An inclusion…”
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11
Nanorobots: An innovative approach for DNA-based cancer treatment
Published in Journal of drug delivery science and technology (01-02-2023)“…Cancer is the 3rd leading cause of death globally and the countries with low-to-middle income account for most cancer cases. The current diagnostic tools…”
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12
In-silico computational analysis of [6-(2, 3-Dichlorophenyl)-1, 2, 4-Triazine-3, 5-Diamine] metal complexes on voltage gated sodium channel and dihydrofolate reductase enzyme
Published in Pakistan journal of pharmaceutical sciences (01-07-2020)“…Epilepsy is the disease associated with seizures and convulsions. Various antiepileptic drugs have been used widely to treat these disorders. Lamotrigine…”
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13
Calycosin-loaded nanostructured lipid carriers: In-vitro and in-vivo evaluation for enhanced anti-cancer potential
Published in Journal of drug delivery science and technology (01-01-2022)“…The purpose of the current study was to explore the suitability of nanostructured lipid carriers (NLCs) loaded with a model drug calycosin for the treatment of…”
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14
Anti-Proliferative and Apoptosis-Inducing Activity of Acacia Modesta and Opuntia Monocantha Extracts on HeLa Cells
Published in Asian Pacific journal of cancer prevention : APJCP (01-10-2020)“…Background: Cancer is one of the leading causes of death in the world. Numerous phytochemicals from plants have shown antineoplastic effects via programmed…”
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Mucoadhesive aprepitant-loaded nanostructured lipid carriers containing sulfhydryl surfactant for enhanced oral drug bioavailability
Published in Journal of drug delivery science and technology (01-09-2024)“…The objective of the study was to design mucoadhesive drug-loaded nanostructured lipid carriers (NLCs) for enhancing the bioavailability of a model BCS Class…”
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16
Compatibility analysis of bergapten with different pharmaceutical excipients used in nanostructured lipid carriers
Published in Pakistan journal of pharmaceutical sciences (01-11-2019)“…In pharmaceuticals sciences, Fourier-transform infrared spectroscopy (FTIR) is a very useful technique to measure the compatibility and interaction between…”
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17
Impact of pharmacist-led interventions in improving adherence to glaucoma medications in the geriatric population
Published in European journal of hospital pharmacy. Science and practice (01-11-2021)“…ObjectivesGeriatric patients can be non-adherent to ophthalmic glaucoma medications because of complex eye drops instillation techniques and forgetfulness, so…”
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CANCER EPIGENETICS AND THE ROLE OF DIETARY ELEMENTS
Published in Gomal journal of medical sciences (30-09-2019)“…Cancer has been a fatal disease since many decades. Over the time, it is presented in multiple ways and is a matter of consideration as accounts for the high…”
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