Search Results - "Arseniyadis, Simeon"

Stimulating excursions into organolead chemistry: modular domino sequences triggered by oxidative cleavage by Abet, Valentina, Castillo, Rafael R., Aquino, Maurizio, Gandara, Zoila, Arseniyadis, Siméon

“…[Display omitted] The present report intends to highlight the main lines of our investigation on a series of modular domino reactions focusing on a multi-task…”
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Identification of marneral synthase, which is critical for growth and development in Arabidopsis by Go, Young S, Lee, Saet B, Kim, Hae J, Kim, Jungmook, Park, Hyo‐Young, Kim, Jeong‐Kook, Shibata, Kyomi, Yokota, Takao, Ohyama, Kiyoshi, Muranaka, Toshiya, Arseniyadis, Siméon, Suh, Mi C

“…Plants produce structurally diverse triterpenoids, which are important for their life and survival. Most triterpenoids and sterols share a common biosynthetic…”
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Diverging Pathways to Topologically Complex Polycyclic Bis-acetals and Their Ring System Interchange by Castillo, Rafael R, Aquino, Maurizio, Gandara, Zoila, Safir, Imad, Elkhayat, Zobida, Retailleau, Pascal, Arseniyadis, Siméon

“…Carbinol-tethered octalin-diols (1), which differ only by the C11 configuration at the angular position, were transformed selectively to three types of…”
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Synthesis of nor-sesquiterpene spirolactones and their steroidal hybrids revisited. The neopentyl dilemma: misassignment of one stereocentre may necessitate a completely new approach by Safir, Imad, Chanu, Angeline, Elkhayat, Zobida, Basak, Ramkrishna, Arseniyadis, Siméon

“…Inversion at the highly congested C1 position of 1-epi-pathylactone A (1-epi-1), or its corresponding steroidal hybrid 8a, using a diverse range of published…”
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Enantioselective Synthesis of Iridal, the Parent Molecule of the Iridal Triterpenoid Class by Corbu, Andrei, Aquino, Maurizio, Pratap, T. V, Retailleau, Pascal, Arseniyadis, Siméon

“…The monocyclic triterpene iridal 1 (parent molecule) is synthesized by an approach that allows access for several representatives of the iridal family as well…”
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Competing Domino Processes: Path-Discriminating Ability of Epoxide Stereochemistry at the Angular Position by Aquino, Maurizio, Safir, Imad, Elkhayat, Zobida, Gandara, Zoila, Perez, Manuel, Retailleau, Pascal, Arseniyadis, Siméon

“…Structurally different products can be reached selectively from unsaturated vicinal bicyclic diols, which differ only by the epoxide configuration at the…”
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Microwave-Accelerated Competing Domino Processes: A Tether-Controlled Dual Pathway into High Molecular Complexity by Elkhayat, Zobida, Safir, Imad, Castellote, Isabel, Retailleau, Pascal, Arseniyadis, Siméon

“…Bicyclic unsaturated diols undergo a path selective modular domino transformation upon subjection to Pb(OAc)4, the reaction being biased to the nature of the…”
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Enantioselective Total Synthesis of 1-epi-Pathylactone A by Chanu, Angéline, Safir, Imad, Basak, Ramkrishna, Chiaroni, Angèle, Arseniyadis, Siméon

“…The first enantioselective total synthesis of 1-epi-pathylactone A, 3, has been accomplished using a PhI(OAc)2-mediated domino reaction as a key step. No…”
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Increasing the Dimensionality of Modular Domino Reactions Triggered by Oxidative Cleavage: A Two-Step Protocol Towards a Variety of Stereodefined Complex Oxygen Heterocycles by Castillo, Rafael R., Abet, Valentina, Aquino, Maurizio, Gandara, Zoila, Retailleau, Pascal, Arseniyadis, Siméon

“…Arylcarbinol‐ and benzyl‐tethered octalin‐diols (1/1′), which differ only by the C11 substitution at the angular position, were transformed selectively into…”
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Modular Construction of Topologically Complex Polycyclic Acetals by Tether-Controlled Domino Reactions by Castillo, Rafael R., Abet, Valentina, Aquino, Maurizio, Gandara, Zoila, Retailleau, Pascal, Arseniyadis, Siméon

“…Lead tetraacetate mediated oxidative cleavage of octalin‐diols (1 and 1′), tethered by variously substituted arenes placed at the angular position (C11), show…”
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Protocols for the preparation of each of the four possible stereoisomeric .alpha.-alkyl-.beta.-hydroxy carboxylic acids from a single chiral aldol reagent by Van Draanen, Nanine A, Arseniyadis, Simeon, Crimmins, Michael T, Heathcock, Clayton H

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A Domino-Based Approach toward Stereodefined Heavily Functionalized Cyclohexanes:  Synthesis of Iridal's Core Structure by Corbu, Andrei, Gauron, Guillaume, Castro, Juan M, Dakir, Mohamed, Arseniyadis, Siméon

“…A stereoselective synthesis of heavily functionalized six-membered ring subunits, which possess functionality at sites appropriate for further elaboration, is…”
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Exploring Modular Domino Reactions:  Competing Processes Based on the Nature of the Angular Substituent by Elkhayat, Zobida, Safir, Imad, Retailleau, Pascal, Arseniyadis, Siméon

“…The octaline diol system 6 was found to undergo an interesting set of reactions upon treatment with PhI(OAc)2, leading, in a single synthetic operation, to…”
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Natural and Unnatural A-seco Terpenes from Pulegone: Synthesis of Galbanic Acid and Marneral Revisited by Corbu, Andrei, Aquino, Maurizio, Perez, Manuel, Gandara, Zoila, Arseniyadis, Siméon

“…We describe herein an improved chiral‐pool strategy for assembling the core structure 3 (both antipodes) of various A‐seco terpenoids that have allowed us to…”
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Synthetic Studies Directed Towards Various Homologues of Natural Sesquiterpene-Coumarin Ethers: The Domino Approach by Corbu, Andrei, Castro, Juan M., Aquino, Maurizio, Gandara, Zoila, Retailleau, Pascal, Arseniyadis, Siméon

“…A domino‐based strategy was used to construct analogues containing the basic skeleton of the monocyclic sesquiterpene‐coumarin ethers galbanic acid (1) and…”
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Efficient Construction of Highly Substituted and Stereodefined cis-Fused Lactones by Elkhayat, Zobida, Safir, Imad, Gandara, Zoila, Retailleau, Pascal, Arseniyadis, Siméon

“…The methodology described in this paper involves the epoxidation of cyclic ene‐acetals to spontaneously generate 6α‐hydroxy‐bis‐acetals that could serve as…”
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Synthesis of a Norsesquiterpene Spirolactone/Steroidal Hybrid by Using an Environmentally Friendly Domino Reaction as a Key Step by Chanu, Angéline, Safir, Imad, Basak, Ramkrishna, Chiaroni, Angèle, Arseniyadis, Siméon

“…A new class of hybrid molecules is accessed by elaborating testosterone's AB ring into the norsesquiterpene spirolactone A′B′ ring. The cyclic ene‐acetal 6b,…”
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Microwave‐Assisted Competing Domino Processes in the Octaline Diol Series by Elkhayat, Zobida, Safir, Imad, Aquino, Maurizio, Perez, Manuel, Gandara, Zoila, Retailleau, Pascal, Arseniyadis, Siméon

“…A Pb(OAc)4‐mediated, path selective, modular domino transformation using an octaline diol framework as a probe is described. Alteration of the nature of the…”
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Microwave-assisted domino reactions: function-compatibility, modulation, and greening efforts by Corbu, Andrei, Gauron, Guillaume, Castro, Juan M., Dakir, Mohamed, Arseniyadis, Siméon

“…Herein we report a microwave-assisted version of a domino protocol, providing ready access to a wide variety of complex oxygen heterocycles. The latter can be…”
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Baeyer-Villiger Oxidation of the Bicyclo[2.2.2]octanone System Revisited: Searching for a Modular Construction of Heavily Substituted Cyclohexanes Based on m-CPBA Mediated Selective Oxygen Insertion by Finet, Laure, Dakir, Mohamed, Castellote, Isabel, Arseniyadis, Siméon

“…Described herein is the use of Baeyer–Villiger oxidation for the selective insertion of oxygen into a variously substituted bicyclo[2.2.2]octanone system,…”
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