Search Results - "Arsenijevic, Y."

Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures by Decembrini, S., Hoehnel, S., Brandenberg, N., Arsenijevic, Y., Lutolf, M. P.

“…The development of improved methods to culture retinal organoids is relevant for the investigation of mechanisms of retinal development under…”
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Animal models for ocular gene therapies by Arsenijevic, Y., Kostic, C.

“…Summary Disease‐causing variants of a large number of genes trigger inherited retinal degeneration leading to photoreceptor loss. Because cones are essential…”
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Hyperactivation of retina by light in mice leads to photoreceptor cell death mediated by VEGF and retinal pigment epithelium permeability by Cachafeiro, M, Bemelmans, A-P, Samardzija, M, Afanasieva, T, Pournaras, J-A, Grimm, C, Kostic, C, Philippe, S, Wenzel, A, Arsenijevic, Y

“…Light toxicity is suspected to enhance certain retinal degenerative processes such as age-related macular degeneration. Death of photoreceptors can be induced…”
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Use of human MAR elements to improve retroviral vector production by Buceta, M, Galbete, J L, Kostic, C, Arsenijevic, Y, Mermod, N

“…Retroviral vectors have many favorable properties for gene therapies, but their use remains limited by safety concerns and/or by relatively lower titers for…”
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Efficient lentiviral gene transfer into corneal stroma cells using a femtosecond laser by Bemelmans, A-P, Arsenijevic, Y, Majo, F

“…We investigated a new procedure for gene transfer into the stroma of pig cornea for the delivery of therapeutic factors. A delimited space was created at 110…”
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In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death by Samardzija, Marijana, Tanimoto, Naoyuki, Kostic, Corinne, Beck, Susanne, Oberhauser, Vitus, Joly, Sandrine, Thiersch, Markus, Fahl, Edda, Arsenijevic, Yvan, von Lintig, Johannes, Wenzel, Andreas, Seeliger, Mathias W., Grimm, Christian

“…RPE65 is a retinoid isomerase required for the production of 11-cis-retinal, the chromophore of both cone and rod visual pigments. We recently established an…”
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Lentiviral vector-mediated gene transfer in adult mouse photoreceptors is impaired by the presence of a physical barrier by Grüter, O, Kostic, C, Crippa, S V, Perez, M-T R, Zografos, L, Schorderet, D F, Munier, F L, Arsenijevic, Y

“…Gene transfer offers a substantial promise for the therapy of degenerative ocular diseases. Lentiviral vectors have the ability to efficiently transduce murine…”
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In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death by Samardzija, M., Tanimoto, N., Kostic, C., Beck, S., Oberhauser, V., Joly, S., Thiersch, M., Fahl, E., Arsenijevic, Y., von Lintig, J., Wenzel, A., Seeliger, M. W., Grimm, C.

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Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina by KOSTIC, C, CHIODINI, F, ARSENIJEVIC, Y, SALMON, P, WIZNEROWICZ, M, DEGLON, N, HORNFELD, D, TRONO, D, AEBISCHER, P, SCHORDERET, D. F, MUNIER, F. L

“…For most retinal degeneration disorders, no efficient treatment exists to preserve photoreceptors (PRs) and, consequently, to maintain vision. Gene transfer…”
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Distribution of vasopressin and oxytocin receptors in the rat spinal cord: sex-related differences and effect of castration in pudendal motor nuclei by Tribollet, E, Barberis, C, Arsenijevic, Y

“…The distribution of vasopressin and oxytocin receptors was established by in vitro autoradiography in the spinal cord of adult rats of either sex, as well as…”
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Differential roles of tumor necrosis factor-alpha and interferon-gamma in mouse hypermetabolic and anorectic responses induced by LPS by Arsenijevic, D, Garcia, I, Vesin, C, Vesin, D, Arsenijevic, Y, Seydoux, J, Girardier, L, Ryffel, B, Dulloo, A, Richard, D

“…Lipopolysaccharide (LPS)-induced effects on energy balance are characterized by alterations in energy expenditure (hypermetabolism) and food intake (anorexia)…”
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Axotomy Induces the Expression of Vasopressin Receptors in Cranial and Spinal Motor Nuclei in the Adult Rat by Tribollet, E., Arsenijevic, Y., Marguerat, A., Barberis, C., Dreifuss, J. J.

“…8-L-Arginine vasopressin ([Arg8]VP) receptors are expressed transiently in the rat facial nucleus during the perinatal period. Electrophysiological studies…”
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Facile Isolation and the Characterization of Human Retinal Stem Cells by Brenda L. K. Coles, Angénieux, Brigitte, Inoue, Tomoyuki, Del Rio-Tsonis, Katia, Spence, Jason R., McInnes, Roderick R., Arsenijevic, Yvan, van der Kooy, Derek, Dryja, Thaddeus P.

“…This study identifies and characterizes retinal stem cells (RSCs) in early postnatal to seventh-decade human eyes. Different subregions of human eyes were…”
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Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice by Bruggeman, Sophia W M, Valk-Lingbeek, Merel E, van der Stoop, Petra P M, Jacobs, Jacqueline J L, Kieboom, Karin, Tanger, Ellen, Hulsman, Danielle, Leung, Carly, Arsenijevic, Yvan, Marino, Silvia, van Lohuizen, Maarten

“…The Polycomb group (PcG) gene Bmi1 promotes cell proliferation and stem cell self-renewal by repressing the Ink4a/Arf locus. We used a genetic approach to…”
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Inhibition of Notch pathway enhances photoreceptor commitment from cultured retinal stem cells by MONTAVON, P, ARSENIJEVIC, Y

“…Purpose Consequently to the principle that photoreceptors have to be at a very precise development stage to be successfully transplanted (MacLaren 2006), we…”
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Vasopressin-binding sites in the pig pituitary gland: competition by novel vasopressin antagonists suggests the existence of an unusual receptor subtype in the anterior lobe by Arsenijevic, Y, Dubois-Dauphin, M, Tribollet, E, Manning, M, Sawyer, W H, Dreifuss, J J

“…Arginine vasopressin (AVP) acts in the pituitary gland, in synergy with corticotrophin-releasing factor, to induce ACTH release in response to stressful…”
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Evaluation of tolerance to lentiviral LV-RPE65 gene therapy vector after subretinal delivery in non-human primates by Matet, Alexandre, Kostic, Corinne, Bemelmans, Alexis-Pierre, Moulin, Alexandre, Rosolen, Serge G., Martin, Samia, Mavilio, Fulvio, Amirjanians, Vazrik, Stieger, Knut, Lorenz, Birgit, Behar-Cohen, Francine, Arsenijevic, Yvan

“…Several approaches have been developed for gene therapy in RPE65-related Leber congenital amaurosis. To date, strategies that have reached the clinical stages…”
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Interactome analysis reveals that FAM161A, deficient in recessive retinitis pigmentosa, is a component of the Golgi-centrosomal network by Di Gioia, Silvio Alessandro, Farinelli, Pietro, Letteboer, Stef J F, Arsenijevic, Yvan, Sharon, Dror, Roepman, Ronald, Rivolta, Carlo

“…Defects in FAM161A, a protein of unknown function localized at the cilium of retinal photoreceptor cells, cause retinitis pigmentosa, a form of hereditary…”
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Towards therapeutic application of ocular stem cells by Pellegrini, Graziella, De Luca, Michele, Arsenijevic, Yvan

“…The first example of cell therapy using cultured stem cells dates back to 1981, when it was demonstrated that human epidermis could be grown in the laboratory…”
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Insulin-Like Growth Factor-I Is a Differentiation Factor for Postmitotic CNS Stem Cell-Derived Neuronal Precursors: Distinct Actions from Those of Brain-Derived Neurotrophic Factor by Arsenijevic, Yvan, Weiss, Samuel

“…Insulin-like growth factor-I (IGF-I) has been reported previously to promote the proliferation, survival, and maturation of sympathetic neuroblasts, the…”
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