Search Results - "Arseni, Lavinia"

From Structure to Phenotype: Impact of Collagen Alterations on Human Health by Arseni, Lavinia, Lombardi, Anita, Orioli, Donata

“…The extracellular matrix (ECM) is a highly dynamic and heterogeneous structure that plays multiple roles in living organisms. Its integrity and homeostasis are…”
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia by Roessner, Philipp M., Llaó Cid, Laura, Lupar, Ekaterina, Roider, Tobias, Bordas, Marie, Schifflers, Christoph, Arseni, Lavinia, Gaupel, Ann-Christin, Kilpert, Fabian, Krötschel, Marit, Arnold, Sebastian J., Sellner, Leopold, Colomer, Dolors, Stilgenbauer, Stephan, Dietrich, Sascha, Lichter, Peter, Izcue, Ana, Seiffert, Martina

“…The transcription factor eomesodermin (EOMES) promotes interleukin (IL)-10 expression in CD4 + T cells, which has been linked to immunosuppressive and…”
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Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients by Öztürk, Selcen, Paul, Yashna, Afzal, Saira, Gil-Farina, Irene, Jauch, Anna, Bruch, Peter-Martin, Kalter, Verena, Hanna, Bola, Arseni, Lavinia, Roessner, Philipp M., Schmidt, Manfred, Stilgenbauer, Stephan, Dietrich, Sascha, Lichter, Peter, Zapatka, Marc, Seiffert, Martina

“…Chronic lymphocytic leukemia (CLL) is a B-cell malignancy mainly occurring at an advanced age with no single major genetic driver. Transgenic expression of…”
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TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin by Arseni, Lavinia, Lanzafame, Manuela, Compe, Emmanuel, tugno, Paola, Afonso-Barroso, António, Peverali, Fiorenzo A, Lehmann, Alan R, Zambruno, Giovanna, Egly, Jean-Marc, Stefanini, Miria, Orioli, Donata

“…Significance Despite exhibiting different phenotypes, the UV-sensitive syndromes trichothiodystrophy (TTD) and xeroderma pigmentosum (XP) result from the same…”
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'The world needs science, and science needs women'…but what do women in science need? – interviews and panel discussion with 5 outstanding female scientists by Arseni, Lavinia

“…Despite great progress in recent years, gender equity in science is still missing. Women are underrepresented in senior/leadership positions and struggle to be…”
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Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair by Sigismondo, Gianluca, Arseni, Lavinia, Palacio-Escat, Nicolàs, Hofmann, Thomas G, Seiffert, Martina, Krijgsveld, Jeroen

“…The DNA damage response (DDR) is essential to maintain genome stability, and its deregulation predisposes to carcinogenesis while encompassing attractive…”
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4.sup.+ T cells in chronic lymphocytic leukemia by Roessner, Philipp M, Llaó Cid, Laura, Lupar, Ekaterina, Roider, Tobias, Bordas, Marie, Schifflers, Christoph, Arseni, Lavinia

“…The transcription factor eomesodermin (EOMES) promotes interleukin (IL)-10 expression in CD4.sup.+ T cells, which has been linked to immunosuppressive and…”
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Reduced levels of prostaglandin I 2 synthase: a distinctive feature of the cancer-free trichothiodystrophy by Lombardi, Anita, Arseni, Lavinia, Carriero, Roberta, Compe, Emmanuel, Botta, Elena, Ferri, Debora, Uggè, Martina, Biamonti, Giuseppe, Peverali, Fiorenzo A, Bione, Silvia, Orioli, Donata

“…The cancer-free photosensitive trichothiodystrophy (PS-TTD) and the cancer-prone xeroderma pigmentosum (XP) are rare monogenic disorders that can arise from…”
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Longitudinal Omics Data Followed By Preclinical Treatment Studies Identify Proteasome Inhibition As Effective Therapy for Ibrutinib-Resistant Chronic Lymphocytic Leukemia by Arseni, Lavinia, Sigismondo, Gianluca, Hermansen, Johanne U, Skånland, Sigrid S, Tausch, Eugen, Stilgenbauer, Stephan, Krijgsveld, Jeroen, Lichter, Peter, Zapatka, Marc, Seiffert, Martina

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Reduced levels of prostaglandin I₂ synthase: a distinctive feature of the cancer-free trichothiodystrophy by Lombardi, Anita, Arseni, Lavinia, Carriero, Roberta, Compe, Emmanuel, Botta, Elena, Ferri, Debora, Uggè, Martina, Biamonti, Giuseppe, Peverali, Fiorenzo A., Bione, Silvia, Orioli, Donata

“…The cancer-free photosensitive trichothiodystrophy (PS-TTD) and the cancer-prone xeroderma pigmentosum (XP) are rare monogenic disorders that can arise from…”
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T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia by Roessner, Philipp M., Seufert, Isabelle, Chapaprieta, Vicente, Jayabalan, Ruparoshni, Briesch, Hannah, Massoni-Badosa, Ramon, Boskovic, Pavle, Benckendorff, Julian, Roider, Tobias, Arseni, Lavinia, Coelho, Mariana, Chakraborty, Supriya, Vaca, Alicia M., Sivina, Mariela, Muckenhuber, Markus, Rodriguez-Rodriguez, Sonia, Bonato, Alice, Herbst, Sophie A., Zapatka, Marc, Sun, Clare, Kretzmer, Helene, Naake, Thomas, Bruch, Peter-Martin, Czernilofsky, Felix, ten Hacken, Elisa, Schneider, Martin, Helm, Dominic, Yosifov, Deyan Y., Kauer, Joseph, Danilov, Alexey V., Bewarder, Moritz, Heyne, Kristina, Schneider, Christof, Stilgenbauer, Stephan, Wiestner, Adrian, Mallm, Jan-Philipp, Burger, Jan A., Efremov, Dimitar G., Lichter, Peter, Dietrich, Sascha, Martin-Subero, José I., Rippe, Karsten, Seiffert, Martina

“…•T-bet acts as a tumor suppressor by enhancing interferon signaling and suppressing proliferation of malignant B cells.•T-bet expression in CLL cells is…”
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Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression by Arseni, Lavinia, Sharma, Rakesh, Mack, Norman, Nagalla, Deepthi, Ohl, Sibylle, Hielscher, Thomas, Singhal, Mahak, Pilz, Robert, Augustin, Hellmut, Sandhoff, Roger, Herold-Mende, Christel, Tews, Björn, Lichter, Peter, Seiffert, Martina

“…Glioblastoma is the most aggressive brain tumor in adults. Treatment failure is predominantly caused by its high invasiveness and its ability to induce a…”
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TFIIH-dependentMMP-1overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin by Arseni, Lavinia, Lanzafame, Manuela, Compe, Emmanuel, Fortugno, Paola, Afonso-Barroso, António, Peverali, Fiorenzo A., Lehmann, Alan R., Zambruno, Giovanna, Egly, Jean-Marc, Stefanini, Miria, Orioli, Donata

“…Mutations in the XPD subunit of the DNA repair/transcription factor TFIIH result in distinct clinical entities, including the cancer-prone xeroderma…”
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