Search Results - "Arsenault, Dany"
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Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
Published in Biology of sex differences (16-11-2020)“…While the higher prevalence of Alzheimer's disease (AD) in women is clear, studies suggest that biological sex may also influence AD pathogenesis. However,…”
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A novel wireless brain stimulation device for long-term use in freely moving mice
Published in Scientific reports (23-04-2019)“…Deep brain stimulation (DBS) has been used in clinical settings for many years despite a paucity of knowledge related to the anatomical and functional…”
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DHA improves cognition and prevents dysfunction of entorhinal cortex neurons in 3xTg-AD mice
Published in PloS one (23-02-2011)“…Defects in neuronal activity of the entorhinal cortex (EC) are suspected to underlie the symptoms of Alzheimer's disease (AD). Whereas neuroprotective effects…”
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Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse
Published in The Journal of physiology (15-05-2006)“…Synapse elimination occurs throughout the nervous system during development, and is essential for the formation of neural circuits. The mechanisms underlying…”
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Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS
Published in PloS one (04-11-2015)“…Parental microglial induced neuroinflammation, triggered by bacterial- or viral infections, can induce neuropsychiatric disorders like schizophrenia and autism…”
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Gain modulation by serotonin in pyramidal neurones of the rat prefrontal cortex
Published in The Journal of physiology (15-07-2005)“…Serotonin (5-HT) is widely implicated in brain functions and diseases. The vertebrate brain is extensively innervated by 5-HT fibres originating from the brain…”
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The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring
Published in Brain, behavior, and immunity (01-05-2014)“…Highlight • Prenatal immune challenges impact on maternal behavior, pup development and expression of various inflammatory and brain cell markers…”
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Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease
Published in Aging (Albany, NY.) (16-05-2017)“…Defects in p21-activated kinase (PAK) lead to dendritic spine abnormalities and are sufficient to cause cognition impairment. The decrease in PAK in the brain…”
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PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ
Published in The Journal of neuroscience (26-06-2013)“…Defects in p21-activated kinase (PAK) are suspected to play a role in cognitive symptoms of Alzheimer's disease (AD). Dysfunction in PAK leads to cofilin…”
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Chronic dietary intake of α-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons
Published in British journal of nutrition (28-04-2012)“…n-3 PUFA are receiving growing attention for their therapeutic potential in central nervous system (CNS) disorders. We have recently shown that long-term…”
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Chronic dietary intake of [alpha]-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons
Published in British journal of nutrition (28-04-2012)“…n-3 PUFA are receiving growing attention for their therapeutic potential in central nervous system (CNS) disorders. We have recently shown that long-term…”
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The morphological and molecular changes of brain cells exposed to direct current electric field stimulation
Published in The international journal of neuropsychopharmacology (01-03-2015)“…The application of low-intensity direct current electric fields has been experimentally used in the clinic to treat a number of brain disorders, predominantly…”
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Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice
Published in Journal of neurochemistry (01-07-2012)“…J. Neurochem. (2012) 122, 427–443. Dietary lipids modify brain fatty acid profile, but evidence of their direct effect on neuronal function is sparse. The…”
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A novel combinational approach of microstimulation and bioluminescence imaging to study the mechanisms of action of cerebral electrical stimulation in mice
Published in The Journal of physiology (15-05-2015)“…Key points We have developed a unique prototype to perform brain stimulation in mice. This system presents a number of advantages and new developments: 1) all…”
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Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in micef
Published in Journal of neurochemistry (01-07-2012)“…J. Neurochem. (2012) 122, 427-443. Dietary lipids modify brain fatty acid profile, but evidence of their direct effect on neuronal function is sparse. The…”
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P1‐414: GLUCOSE SUPPRESSES AKINESIA EPISODES AND REDUCES AMYLOID PATHOLOGY IN THE 3XTG‐AD MOUSE MODEL OF ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2014)Get full text
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GLUCOSE SUPPRESSES AKINESIA EPISODES AND REDUCES AMYLOID PATHOLOGY IN THE 3XTG-AD MOUSE MODEL OF ALZHEIMER'S DISEASE
Published in Alzheimer's & dementia (01-07-2014)Get full text
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O5‐01‐02: Defects in p21‐activated kinase (PAK) in Alzheimer's disease: A causal role?
Published in Alzheimer's & dementia (01-07-2012)Get full text
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Defects in p21-activated kinase (PAK) in Alzheimer's disease: A causal role?
Published in Alzheimer's & dementia (01-07-2012)Get full text
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