Search Results - "Arrigoni, Chiara"
-
1
Chronic Monteggia in pediatric population: A narrative literature review
Published in La Pediatria medica e chirurgica (28-10-2022)“…Monteggia lesion is a traumatic condition that affects the forearm and is characterized by the association of an ulna fracture with a dislocation of the radius…”
Get full text
Journal Article -
2
In Vitro Co-Culture Models of Breast Cancer Metastatic Progression towards Bone
Published in International journal of molecular sciences (25-08-2016)“…Advanced breast cancer frequently metastasizes to bone through a multistep process involving the detachment of cells from the primary tumor, their…”
Get full text
Journal Article -
3
Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach
Published in Biomaterials (01-01-2016)“…Abstract The generation of functional, vascularized tissues is a key challenge for both tissue engineering applications and the development of advanced…”
Get full text
Journal Article -
4
Engineered miniaturized models of musculoskeletal diseases
Published in Drug discovery today (01-09-2016)“…•Miniaturized 3D in vitro models are effective tools to study musculoskeletal diseases.•Main advantages: highly controlled conditions, low cell amount and…”
Get full text
Journal Article -
5
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Published in Nature communications (15-05-2020)“…Ewing sarcoma (EwS) is an aggressive childhood cancer likely originating from mesenchymal stem cells or osteo-chondrogenic progenitors. It is characterized by…”
Get full text
Journal Article -
6
Advanced Microfluidic Models of Cancer and Immune Cell Extravasation: A Systematic Review of the Literature
Published in Frontiers in bioengineering and biotechnology (26-08-2020)“…Extravasation is a multi-step process implicated in many physiological and pathological events. This process is essential to get leukocytes to the site of…”
Get full text
Journal Article -
7
Complex or not too complex? One size does not fit all in next generation microphysiological systems
Published in iScience (15-03-2024)“…In the attempt to overcome the increasingly recognized shortcomings of existing in vitro and in vivo models, researchers have started to implement alternative…”
Get full text
Journal Article -
8
A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions
Published in Materials today bio (15-12-2022)“…The organ-specific metastatization of breast cancer to bone is driven by specific interactions between the host microenvironment and cancer cells (CCs)…”
Get full text
Journal Article -
9
Umbilical Cord MSCs and Their Secretome in the Therapy of Arthritic Diseases: A Research and Industrial Perspective
Published in Cells (Basel, Switzerland) (28-05-2020)“…The prevalence of arthritic diseases is increasing in developed countries, but effective treatments are currently lacking. The injection of mesenchymal stem…”
Get full text
Journal Article -
10
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma
Published in Molecular cancer (03-01-2022)“…Similar in vitro and in vivo experiments performed with both cell lines ‘empty’ controls exhibited no significant differences (Supplementary Fig. 2a, c-d,…”
Get full text
Journal Article -
11
Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
Published in Nature communications (23-11-2020)“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20017-2…”
Get full text
Journal Article -
12
Herringbone-like hydrodynamic structures in microchannels: A CFD model to evaluate the enhancement of surface binding
Published in Medical engineering & physics (01-10-2017)“…•Simulations of flow, diffusion and binding were performed in specific microchannel segment models.•Results were used to investigate the local concentration of…”
Get full text
Journal Article -
13
A personalized osteoarthritic joint-on-a-chip as a screening platform for biological treatments
Published in Materials today bio (01-06-2024)“…Osteoarthritis (OA) is a highly disabling pathology, characterized by synovial inflammation and cartilage degeneration. Orthobiologics have shown promising…”
Get full text
Journal Article -
14
Differential angiogenesis of bone and muscle endothelium in aging and inflammatory processes
Published in Communications biology (31-01-2023)“…Different tissues have different endothelial features, however, the implications of this heterogeneity in pathological responses are not clear yet…”
Get full text
Journal Article -
15
Rational Design of Prevascularized Large 3D Tissue Constructs Using Computational Simulations and Biofabrication of Geometrically Controlled Microvessels
Published in Advanced healthcare materials (01-07-2016)“…A major challenge in the development of clinically relevant 3D tissue constructs is the formation of vascular networks for oxygenation, nutrient supply, and…”
Get full text
Journal Article -
16
Vascular tissue engineering
Published in Cell transplantation (2006)“…Reconstructive surgery using autologous vessels is the conventional approach for substitution of diseased vessels or for generation of bypass to improve blood…”
Get full text
Journal Article -
17
Adult Hip Flexion Contracture due to Neurological Disease: A New Treatment Protocol-Surgical Treatment of Neurological Hip Flexion Contracture
Published in Case Reports in Medicine (01-01-2014)“…Congenital, traumatic, or extrinsic causes can lead people to paraplegia; some of these are potentially; reversible and others are not. Paraplegia can couse…”
Get full text
Journal Article -
18
Organs-on-a-chip as model systems for multifactorial musculoskeletal diseases
Published in Current opinion in biotechnology (01-06-2020)“…[Display omitted] •The study of multifactorial diseases needs in vitro models involving complex interactions.•Model complexity can be of biological or…”
Get full text
Journal Article -
19
3D Biofabricated In Vitro Models of Vascularized and Mineralized Bone Tissues
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…This protocol describes a comprehensive practical guide for the biofabrication of 3D in vitro models of vascularized and mineralized bone Minitissues. These…”
Get more information
Journal Article -
20
2302: Development of Pancreatic Ductal AdenoCarcinoma on-chip for radiobiological applications
Published in Radiotherapy and oncology (01-05-2024)Get full text
Journal Article