Search Results - "Arrigo, A P"

HspB1 dynamic phospho-oligomeric structure dependent interactome as cancer therapeutic target by Arrigo, A-P, Gibert, B

“…Human HspB1 (Hsp27), a molecular chaperone bearing tumorigenic and metastatic roles, is characterized by its dynamic phosphorylation and heterogenous…”
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Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo by Gibert, B, Eckel, B, Gonin, V, Goldschneider, D, Fombonne, J, Deux, B, Mehlen, P, Arrigo, A-P, Clézardin, P, Diaz-Latoud, C

“…Background: The small stress heat shock protein 27 (Hsp27) has recently turned as a promising target for cancer treatment. Hsp27 upregulation is associated…”
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Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers by Gibert, B, Hadchity, E, Czekalla, A, Aloy, M-T, Colas, P, Rodriguez-Lafrasse, C, Arrigo, A-P, Diaz-Latoud, C

“…Human heat shock protein 27 (Hsp27, HspB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a…”
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The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system by Franklin, T B, Krueger-Naug, A M, Clarke, D B, Arrigo, A-P, Currie, R W

“…Heat shock proteins (Hsps) are highly conserved and under physiological conditions act as molecular chaperones and/or have anti-apoptotic activities…”
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Expression and functions of heat shock proteins in the normal and pathological mammalian eye by Arrigo, A-P, Simon, S

“…Heat shock proteins (Hsps) are expressed in mammalian embryonic, adult and aging lens, cornea and retina. These proteins, particularly those belonging to the…”
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Sumoylation in Lens Differentiation and Pathogenesis by Xiang, J-W, Chen, Z-G, Gong, L, Xiao, Y, Qing, W-J, Wang, L, Hu, X-H, Huang, Z-X, Qi, R-L, Yang, T-H, Arrigo, A-P, Zhang, L, Tang, X-C, Huang, S, Liu, F-Y, Luo, Z-W, Liu, Y-F, Sun, Q, Gigantelli, J, Liu, Y-Z, Li, D W-C

“…Sumoylation, a post-translational modification discovered over a decade ago, turns out to be a very important regulatory mechanism mediating multiple cellular…”
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Gene expression and the thiol redox state by Arrigo, André-Patrick

“…The intracellular redox status is a tightly regulated parameter which provides the cell with an optimal ability to counteract the highly oxidizing…”
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Protection against heat and staurosporine mediated apoptosis by the HSV-1 US11 protein by Javouhey, E, Gibert, B, Arrigo, A.-P, Diaz, J.J, Diaz-Latoud, C

“…Abstract US11 protein, one of herpes simplex virus type 1 (HSV-1) true late gene products, plays a role in the virally induced post-transcriptional control of…”
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Pathology-Dependent Effects Linked to Small Heat Shock Proteins Expression : An Update by Arrigo, A.-P.

“…Small heat shock proteins (small Hsps) are stress-induced molecular chaperones that act as holdases towards polypeptides that have lost their folding in stress…”
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Small stress proteins: chaperones that act as regulators of intracellular redox state and programmed cell death by Arrigo, A P

“…Small stress proteins (sHsp) are molecular chaperones whose expression was shown to enhance the survival of mammalian cells exposed to numerous types of…”
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Activation of the hsp70 promoter by environmental inorganic and organic chemicals: relationships with cytotoxicity and lipophilicity by Aı̈t-Aı̈ssa, S, Porcher, J.-M, Arrigo, A.-P, Lambré, C

“…Stress proteins (heat shock proteins, HSPs) have been proposed as general markers of cellular aggression and their use for environmental monitoring is often…”
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Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts by Mehlen, P, Preville, X, Chareyron, P, Briolay, J, Klemenz, R, Arrigo, A P

“…Hyperthermia and other forms of stress that induce and/or stimulate heat shock or stress protein (hsp) expression enhance the cellular resistance to TNF-alpha…”
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HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs by GARRIDO, C, OTTAVI, P, FROMENTIN, A, HAMMANN, A, ARRIGO, A.-P, CHAUFFERT, B, MEHLEN, P

“…Resistance of colorectal cancer cells to chemotherapeutic drugs increases as cells reach confluence. Here we show that the small stress protein HSP27, which…”
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hsp27 as a Switch between Differentiation and Apoptosis in Murine Embryonic Stem Cells by Mehlen, Patrick, Mehlen, Anne, Godet, Jacqueline, Arrigo, André-Patrick

“…Small stress proteins are developmentally regulated and linked to cell growth and differentiation. The early phase of murine embryonic stem (ES) cell…”
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Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones by GARRIDO, C, FROMENTIN, A, BONNOTTE, B, FAVRE, N, MOUTET, M, ARRIGO, A.-P, MEHLEN, P, SOLARY, E

“…The REG and PRO cell clones were obtained from a colon adenocarcinoma induced in a BDIX rat by 1,2-dimethylhydrazine. When injected s.c. into syngeneic hosts,…”
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Chemical stress sensitive luminescent human cells: Molecular biology approach using inducible Drosophila melanogaster hsp22 promoter by Mandon, C.A., Diaz, C., Arrigo, A.-P., Blum, L.J.

“…A whole-cell bioassay has been developed for the total toxicity testing of liquid samples. The method is based on the induction of the bioluminescent activity…”
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Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo by BRUEY, Jean-Marie, PAUL, Catherine, FROMENTIN, Annie, HILPERT, Sophie, ARRIGO, André-Patrick, SOLARY, Eric, GARRIDO, Carmen

“…HSP27 form oligomeric structures up to 800 Kda. In cultured cells, the equilibrium between small and large oligomers shifted towards smaller oligomers when…”
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Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein by ARRIGO, A.-P, SUHAN, J. P, WELCH, W. J

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dithiocarbamate fungicide thiram detection: Comparison of bioluminescent and fluorescent whole-cell bioassays based on hsp22 stress promoter induction by Mandon, C.A., Diaz-Latoud, C., Arrigo, A.-P., Blum, L.J.

“…Detection of toxic substances interfering with endocrine system is one of the major preoccupations of the European community. A whole-cell bioassay for…”
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Inhibition of IκB-α Phosphorylation and Degradation and Subsequent NF-κB Activation by Glutathione Peroxidase Overexpression by Kretz-Remy, Carole, Mehlen, Patrick, Mirault, Marc-Edouard, Arrigo, André-Patrick

“…We report here that both κB-dependent transactivation of a reporter gene and NF-κB activation in response to tumor necrosis factor (TNFα) or H2O2treatments are…”
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