Search Results - "Arredouani, M"

Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4 by Sowalsky, Adam G, Kissick, Haydn T, Gerrin, Sean J, Schaefer, Rachel J, Xia, Zheng, Russo, Joshua W, Arredouani, M Simo, Bubley, Glenn J, Sanda, Martin G, Li, Wei, Ye, Huihui, Balk, Steven P

“…The molecular features that account for the distinct histology and aggressive biological behavior of Gleason pattern 4 (Gp4) versus Gp3 prostate cancer, and…”
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Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model by Varghese, Bindu, Lynch, Lydia, Vriend, Lianne E., Draganov, Dobrin, Clark, Justice M., Kissick, Haydn T., Varghese, Sharlin, Sanda, Martin G., Dranoff, Glenn, Arredouani, M. Simo, Balk, Steven P., Exley, Mark A.

“…Invariant natural killer T cells (iNKT cells) express a semi-invariant T cell receptor that recognizes certain glycolipids (including α-galactosylceramide,…”
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Haptoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release by Arredouani, M., Matthijs, P., Van Hoeyveld, E., Kasran, A., Baumann, H., Ceuppens, J. L., Stevens, E.

“…Summary T helper cell type 1 (Th1) and type 2 (Th2) immune responses are characterized by a different pattern of cytokine expression following T‐cell…”
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The structure and function of marco, a macrophage class a scavenger receptor by Arredouani, M S, Kobzik, L

“…The class A scavenger receptors are important in many aspects of macrophage biology. The receptor MARCO is a relatively recently described member of this…”
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Haptoglobin Interacts with the Human Mast Cell Line HMC‐1 and Inhibits its Spontaneous Proliferation by El‐Ghmati, S. M., Arredouani, M., Van Hoeyveld, E. M., Ceuppens, J. L., Stevens, E. A. M.

“…Haptoglobin (Hp) is an acute phase reactant produced by hepatocytes. There is evidence for an immunomodulatory potential of Hp, though there is no clear…”
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Haptoglobin and the Th1/Th2 balance: hints from in vitro and in vivo studies by Arredouani, M, Matthys, P, Kasran, A, Baumann, H, Ceuppen, J L

“…A variety of immunomodulatory effects have previously been attributed to haptoglobin (Hp). These are supposed to be partly mediated through binding of Hp to…”
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Androgens modulate anti-tumor immunity through interference with the T lymphocyte differentiation program (P1169) by Arredouani, M. Simo, Kissick, Haydn, Dunn, Laura, Sanda, Martin

“…Abstract Androgen modulation of immunity to tumor antigens have implications on designing novel prostate cancer immunotherapy regimens. However, the mechanisms…”
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The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles by Arredouani, Mohamed, Yang, Zhiping, Ning, YaoYu, Qin, Guozhong, Soininen, Raija, Tryggvason, Karl, Kobzik, Lester

“…Alveolar macrophages (AMs) express the class A scavenger receptor macrophage receptor with collagenous structure (MARCO), but its role in vivo in lung defense…”
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Scavenger receptor class-A is a novel cell surface receptor for double-stranded RNA by Limmon, Gino V, Arredouani, Mohamed, McCann, Kelly L, Minor, Radiah A. Corn, Kobzik, Lester, Imani, Farhad

“…Double-stranded RNA (dsRNA) is a potent signal to the host immune system for the presence of an ongoing viral infection. The presence of dsRNA, intracellularly…”
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Distinct transcriptome of regulatory T cells in prostate cancer (162.18) by Arredouani, M. Simo, Kissick, Haydn, Dunn, Laura, Sanda, Martin

“…Abstract The inhibitory role of regulatory T-cells (Tregs) in cancer is now well established. Furthermore, inhibition of Treg function has been shown both…”
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Disparate Regulation and Function of the Class A Scavenger Receptors SR-AI/II and MARCO by Jozefowski, Szczepan, Arredouani, Mohamed, Sulahian, Timothy, Kobzik, Lester

“…The macrophage class A scavenger receptors, macrophage receptor with a collagenous structure (MARCO) and type I/II class A scavenger receptor (SR-AI/II), share…”
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Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II by Dahl, Morten, Bauer, Alison K, Arredouani, Mohamed, Soininen, Raija, Tryggvason, Karl, Kleeberger, Steven R, Kobzik, Lester

“…Alveolar macrophages (AMs) express the class A scavenger receptors (SRAs) macrophage receptor with collagenous structure (MARCO) and scavenger receptor AI/II…”
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Abstract A31: Human prostate cancer transcriptome reveals distinct signaling pathway dysregulations associated with TMPRSS2:ERG fusion by Bhasin, Manoj, Lu, Bin, Arredouani, M. Simo

“…Abstract Introduction: The gene rearrangement leading to the fusion of the TMPRSS2 and ERG genes on chromosome 21 occurs in about 50% of prostate cancer cases…”
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Immunogenic Peptides Derived from the Transcription Factor ERG as a Vaccine for Prostate Cancer (162.17) by Kissick, Haydn, Dunn, Laura, Lu, Bin, Sanda, Martin, Arredouani, M. Simo

“…Abstract The suitability of immunotherapy as a treatment for prostate cancer (PCa) has recently been demonstrated in a number of clinical trials. While these…”
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Breaking immune tolerance to prostate-associated tumor antigens through Tim-1 receptor (162.20) by Arredouani, M. Simo, Kissick, Haydn, Dunn, Laura, Strom, Terry, Sanda, Martin

“…Abstract It has been suggested that one factor limiting cancer immunotherapy in clinical trials are immunological checkpoints that impede vaccine-induced…”
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A novel iNKT-mediated vaccine maneuver overcomes PD-1-mediated T cell exhaustion in cancer (165.13) by Varghese, Bindu, Lynch, Lydia, Vriend, Lianne, Kissick, Haydn, Dunn, Laura, Varghese, Sharlin, Arredouani, M. Simo, Balk, Steven, Exley, Mark

“…Abstract Our immune system plays an important role in preventing cancer. However, tumor-derived immuno-suppression hinders effective anti-tumor immunity. T…”
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Role of scavenger receptor MARCO in macrophage responses to CpG oligodeoxynucleotides by Jozefowski, S, Sulahian, TH, Arredouani, M, Kobzik, L

“…The macrophage Class A scavenger receptor MARCO (macrophage receptor with a collagenous structure) functions as a pattern‐recognition receptor for bacterial…”
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A novel iNKT cell-mediated vaccine maneuver induces potent long-lasting anti-tumor immunity for advanced prostate cancer by boosting CD8+T cell memory and function (53.24) by Varghese, Bindu, Lynch, Lydia, Vriend, Lianne, Kissick, Haydn, Dunn, Laura, Varghese, Sharlin, Dranoff, Glenn, Arredouani, M. Simo, Balk, Steven, Exley, Mark

“…Abstract iNKT cells have considerable therapeutic promise in cancer, but so far this has not been fully realized. At issue has been delivering iNKT ligand and…”
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Optimizing anti‐tumor immunity: Mechanisms and reversion of systemic iNKT defects in murine prostate cancer by Nowak, Michael, Ilyinski, Petr, Arredouani, M. Simo, Sanda, Martin, Balk, Stephen P, Exley, Mark A

“…Abstract only Breaking tolerance to self‐antigens represents a promising treatment approach, especially for cancers of noncritical organs. Invariant natural…”
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Exploiting the Good Guys: Th1 Antiviral & Antitumor Human & Mouse NKT Cells by Exley, Mark, Nowak, Michael, Yue, Simon, Scheuplein, Felix, Arredouani, M. Simo, Sanda, Martin, Sasada, Tetsuro, Balk, Steven

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