Search Results - "Arrate, Maria Pia"

MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer by Edmonds, Mick D, Boyd, Kelli L, Moyo, Tamara, Mitra, Ramkrishna, Duszynski, Robert, Arrate, Maria Pia, Chen, Xi, Zhao, Zhongming, Blackwell, Timothy S, Andl, Thomas, Eischen, Christine M

“…MicroRNA (miR) are important regulators of gene expression, and aberrant miR expression has been linked to oncogenesis; however, little is understood about…”
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MicroRNA Biogenesis Is Required for Myc-Induced B-Cell Lymphoma Development and Survival by ARRATE, Maria Pia, VINCENT, Tiffaney, ODVODY, Jessica, KAR, Rekha, JONES, Stephen N, EISCHEN, Christine M

“…Many tumor cells express globally reduced levels of microRNAs (miRNA), suggesting that decreased miRNA expression in premalignant cells contributes to their…”
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Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo by Ni, Chang-Yuan, Wu, Zhao-Hui, Florence, William C, Parekh, Vrajesh V, Arrate, Maria Pia, Pierce, Steven, Schweitzer, Brock, Van Kaer, Luc, Joyce, Sebastian, Miyamoto, Shigeki, Ballard, Dean W, Oltz, Eugene M

“…Transcription factor NF-kappaB controls the expression of multiple genes involved in immunity and inflammation. The initial activation and duration of…”
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A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia by Ramsey, Haley E, Fischer, Melissa A, Lee, Taekyu, Gorska, Agnieszka E, Arrate, Maria Pia, Fuller, Londa, Boyd, Kelli L, Strickland, Stephen A, Sensintaffar, John, Hogdal, Leah J, Ayers, Gregory D, Olejniczak, Edward T, Fesik, Stephen W, Savona, Michael R

“…Suppression of apoptosis by expression of antiapoptotic BCL2 family members is a hallmark of acute myeloblastic leukemia (AML). Induced myeloid leukemia cell…”
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Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis by GRIEB, Brian C, GRAMLING, Mark W, ARRATE, Maria Pia, XI CHEN, BEAUPARLANT, Stephen L, HAINES, Dale S, HUA XIAO, EISCHEN, Christine M

“…Despite its involvement in most human cancers, MYC continues to pose a challenge as a readily tractable therapeutic target. Here we identify the MYC…”
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Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution by Puccetti, M V, Fischer, M A, Arrate, M P, Boyd, K L, Duszynski, R J, Bétous, R, Cortez, D, Eischen, C M

“…DNA replication stress promotes genome instability in cancer. However, the contribution of the replication stress response to the development of malignancies…”
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Mdmx promotes genomic instability independent of p53 and Mdm2 by Carrillo, A M, Bouska, A, Arrate, M P, Eischen, C M

“…The oncogene Mdmx is overexpressed in many human malignancies, and together with Mdm2, negatively regulates the p53 tumor suppressor. However, a…”
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A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis by Odvody, J, Vincent, T, Arrate, M P, Grieb, B, Wang, S, Garriga, J, Lozano, G, Iwakuma, T, Haines, D S, Eischen, C M

“…Mdm2 binding protein (MTBP) has been implicated in cell-cycle arrest and the Mdm2/p53 tumor suppressor pathway through its interaction with Mdm2. To determine…”
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