Search Results - "Arranz, Mariano García"

Current and Emerging Applications of Droplet Digital PCR in Oncology by Olmedillas-López, Susana, García-Arranz, Mariano, García-Olmo, Damián

“…The clinical management of cancer has evolved in recent years towards more personalized strategies that require a comprehensive knowledge of the complex…”
Get full text

Current and Emerging Applications of Droplet Digital PCR in Oncology: An Updated Review by Olmedillas-López, Susana, Olivera-Salazar, Rocío, García-Arranz, Mariano, García-Olmo, Damián

“…In the era of personalized medicine and targeted therapies for the management of patients with cancer, ultrasensitive detection methods for tumor genotyping,…”
Get full text

Oncological transformation in vitro of hepatic progenitor cell lines isolated from adult mice by Olivera-Salazar, Rocío, García-Arranz, Mariano, Sánchez, Aránzazu, Olmedillas-López, Susana, Vega-Clemente, Luz, Serrano, Luis Javier, Herrera, Blanca, García-Olmo, Damián

“…Colorectal cancer cells can transfer the oncogene KRAS to distant cells, predisposing them to malignant transformation (Genometastasis Theory). This process…”
Get full text

Application of adipose tissue-derived stem cells in a rat rotator cuff repair model by Mora, Maria Valencia, Antuña, Samuel Antuña, Arranz, Mariano García, Carrascal, Maria Teresa, Barco, Raúl

“…ABSTRACT Introduction Healing tissue of the rotator cuff does not regenerate the native enthesis; fibrovascular scar tissue is formed instead and this has less…”
Get full text

Cell-Free Nucleic Acids Circulating in the Plasma of Colorectal Cancer Patients Induce the Oncogenic Transformation of Susceptible Cultured Cells by GARCIA-OLMO, Dolores C, DOMINGUEZ, Carolina, GARCIA-ARRANZ, Mariano, ANKER, Phillipe, STROUN, Maurice, GARCIA-VERDUGO, José M, GARCIA-OLMO, Damián

“…It has been proposed that cell-free nucleic acids in the plasma participate in tumorigenesis and the development of metastases via transfection-like uptake of…”
Get full text

HIV-reservoir size is not affected either by HCV coinfection or by direct acting antivirals (DAAs) therapy by Álvarez, Beatriz, Navarrete-Muñoz, María A., Briz, Veronica, Olmedillas-López, Susana, Nistal, Sara, Cabello, Alfonso, Prieto, Laura, Górgolas, Miguel, García-Arranz, Mariano, Benito, José M., Rallón, Norma

“…The role of HCV on the HIV reservoir is controversial since the reduction on HIV-DNA levels after HCV eradication with IFNα/RBV treatment seems to be the…”
Get full text

A phase I clinical trial of the treatment of crohn's fistula by adipose mesenchymal stem cell transplantation by GARCIA-OLMO, Damian, GARCIA-ARRANZ, Mariano, HERREROS, Dolores, PASCUAL, Isabel, PEIRO, Concepcion, RODRIGUEZ-MONTES, José Antonio

“…The effective management of fistulas in patients with Crohn's disease presents an extremely challenging problem. Mesenchymal adult stem cells extracted from…”
Get full text

Redefining synchronous colorectal cancers based on tumor clonality by Perea, José, García, Juan L., Corchete, Luis, Lumbreras, Eva, Arriba, María, Rueda, Daniel, Tapial, Sandra, Pérez, Jessica, Vieiro, Victoria, Rodríguez, Yolanda, Brandáriz, Lorena, García‐Arranz, Mariano, García‐Olmo, Damián, Goel, Ajay, Urioste, Miguel, Sarmiento, Rogelio González

“…To analyze the possible clonal origin of a part of Synchronous colorectal cancer (SCRC), we studied 104 paired‐SCRCs from 52 consecutive patients without…”
Get full text

The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer by Shelton, Phillip M., Duran, Angeles, Nakanishi, Yuki, Reina-Campos, Miguel, Kasashima, Hiroaki, Llado, Victoria, Ma, Li, Campos, Alex, García-Olmo, Damián, García-Arranz, Mariano, García-Olmo, Dolores C., Olmedillas-López, Susana, Caceres, Javier F., Diaz-Meco, Maria T., Moscat, Jorge

“…Most colorectal cancer (CRC)-related deaths are due to liver metastases. PKCζ is a tumor suppressor in CRC with reduced expression in metastasis. Given the…”
Get full text

The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy by García-Bernal, David, García-Arranz, Mariano, Yáñez, Rosa M, Hervás-Salcedo, Rosario, Cortés, Alfonso, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Óscar, Bueren, Juan A, García-Olmo, Damián, Moraleda, Jose M, Segovia, José C, Zapata, Agustín G

“…Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in advanced therapies with different purposes, most of which are…”
Get full text

Mesenchymal stem cells: biological properties and clinical applications by García-Gómez, Ignacio, Elvira, Gema, Zapata, Agustín G, Lamana, María L, Ramírez, Manuel, Castro, Javier García, Arranz, Mariano García, Vicente, Angeles, Bueren, Juan, García-Olmo, Damián

“…In the last decade, knowledge of mesenchymal stem cells (MSCs) has evolved rapidly; their immunomodulatory properties and paracrine interactions with specific…”
Get more information

Understanding CAR T cell therapy and its role in ovarian cancer and peritoneal carcinomatosis from ovarian cancer by Domínguez-Prieto, Víctor, Qian, Siyuan, Villarejo-Campos, Pedro, Meliga, Cecilia, González-Soares, Sara, Guijo Castellano, Ismael, Jiménez-Galanes, Santos, García-Arranz, Mariano, Guadalajara, Héctor, García-Olmo, Damián

“…Ovarian cancer is the seventh most common cancer worldwide in women and the most lethal gynecologic malignancy due to the lack of accurate screening tools for…”
Get full text

Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10 by Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Oscar, Segovia, Jose-Carlos, Alvarez-Silva, Marcio, García-Arranz, Mariano, Minguez, Pablo, Del Pozo, Victoria, de Alba, Marta Rodríguez, García-Olmo, Damián, Ayuso, Carmen, Lamana, María Luisa, Bueren, Juan A, Yañez, Rosa María

“…Mesenchymal stromal cells (MSCs) constitute one of the cell types most frequently used in cell therapy. Although several studies have shown the efficacy of…”
Get full text

Airway transplantation of adipose stem cells protects against bleomycin-induced pulmonary fibrosis by Llontop, Pedro, Lopez-Fernandez, Daniel, Clavo, Bernardino, Afonso Martín, Juan Luis, Fiuza-Pérez, María D, García Arranz, Mariano, Calatayud, Joaquín, Molins López-Rodó, Laureano, Alshehri, Khalid, Ayub, Adil, Raad, Wissam, Bhora, Faiz, Santana-Rodríguez, Norberto

“…Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis. Adipose-derived stem cells (ADSC) have demonstrated…”
Get full text

Liquid biopsy in peritoneal fluid and plasma as a prognostic factor in advanced colorectal and appendiceal tumors after complete cytoreduction and hyperthermic intraperitoneal chemotherapy by López-Rojo, Irene, Olmedillas-López, Susana, Villarejo Campos, Pedro, Domínguez Prieto, Víctor, Barambio Buendía, Javier, Cortés Guiral, Delia, García-Arranz, Mariano, García-Olmo, Damián

“…Background: Positive cytology has been identified as an independent negative prognostic factor in patients with peritoneal metastases (PM) of colorectal…”
Get full text

Graft infusion of adipose‐derived mesenchymal stromal cells to prevent rejection in experimental intestinal transplantation: A feasibility study by Andres, Ane M., Stringa, Pablo, Talayero, Paloma, Santamaria, Monica, García‐Arranz, Mariano, García Gómez‐Heras, Soledad, Largo‐Aramburu, Carlota, Aras‐Lopez, Rosa M., Vallejo‐Cremades, Maria Teresa, Guerra Pastrián, Laura, Vega, Luz, Encinas, Jose Luis, Lopez‐Santamaria, Manuel, Hernández‐Oliveros, Francisco

“…Background Mesenchymal stromal cells (MSC) have been proposed as a promising complement to standard immunosuppression in solid organ transplantation because of…”
Get full text

Detection of KRAS G12D in colorectal cancer stool by droplet digital PCR by Susana Olmedillas-López Dennis César Lévano-Linares Carmen Laura Aúz Alexandre Luz Vega-Clemente Edurne León Sánchez Alejandro Villagrasa Jaime Ruíz-Tovar Mariano García-Arranz Damián García-Olmo

“…AIM To assess KRAS G12 D mutation detection by droplet digital PCR(dd PCR) in stool-derived DNA from colorectal cancer(CRC) patients.METHODS In this study,…”
Get full text

Biodistribution, long-term survival, and safety of human adipose tissue-derived mesenchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging by Vilalta, Marta, Dégano, Irene R, Bagó, Juli, Gould, David, Santos, Mònica, García-Arranz, Mariano, Ayats, Ramon, Fuster, Carme, Chernajovsky, Yuti, García-Olmo, Damián, Rubio, Nuria, Blanco, Jerónimo

“…Cultivated murine bone marrow mesenchymal stem cells (MSCs) frequently accumulate chromosome abnormalities, become oncogenically transformed, and generate…”
Get more information

Liquid biopsy by NGS: differential presence of exons (DPE) in cell‐free DNA reveals different patterns in metastatic and nonmetastatic colorectal cancer by Olmedillas‐López, Susana, García‐Olmo, Dolores C., García‐Arranz, Mariano, Peiró‐Pastor, Ramón, Aguado, Begoña, García‐Olmo, Damián

“…Next‐generation sequencing (NGS) has been proposed as a suitable tool for liquid biopsy in colorectal cancer (CRC), although most studies to date have focused…”
Get full text

Chemical Scalpel: An Experimental Collagenase-Based Treatment for Peritoneal Adhesions by Barambio, Javier, García-Arranz, Mariano, Villarejo Campos, Pedro, Vélez Pinto, Juan Felipe, Clemente, Luz Vega, Gómez-Heras, Soledad García, Guadalajara, Héctor, García-Olmo, Damián

“…(1) Background: Abdominal adhesions are a common disease appearing after any type of abdominal surgery and may prolong surgical time and cause intestinal…”
Get full text