Search Results - "Arpawong, Thalida"

Associations Between Longitudinal Loneliness, DNA Methylation Age Acceleration, and Cognitive Functioning by Lynch, Morgan, Em Arpawong, Thalida, Beam, Christopher R

“…Abstract Objectives Loneliness may influence aging biomarkers related to cognitive functioning, for example, through accelerated DNA methylation (DNAm) aging…”
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Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort by Arpawong, Thalida E, Pendleton, Neil, Mekli, Krisztina, McArdle, John J, Gatz, Margaret, Armoskus, Chris, Knowles, James A, Prescott, Carol A

“…Verbal memory is typically studied using immediate recall (IR) and delayed recall (DR) scores, although DR is dependent on IR capability. Separating these…”
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The dynamic association between body mass index and cognition from midlife through late-life, and the effect of sex and genetic influences by Karlsson, Ida K., Gatz, Margaret, Arpawong, Thalida Em, Dahl Aslan, Anna K., Reynolds, Chandra A.

“…Body mass index (BMI) is associated with cognitive abilities, but the nature of the relationship remains largely unexplored. We aimed to investigate the…”
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Female vulnerability to the effects of smoking on health outcomes in older people by Haghani, Amin, Arpawong, Thalida Em, Kim, Jung Ki, Lewinger, Juan Pablo, Finch, Caleb E, Crimmins, Eileen

“…Cigarette smoking is among the leading risk factors for mortality and morbidity. While men have a higher smoking prevalence, mechanistic experiments suggest…”
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Frailty Index associates with GRIN2B in two representative samples from the United States and the United Kingdom by Mekli, Krisztina, Stevens, Adam, Marshall, Alan D, Arpawong, Thalida E, Phillips, Drystan F, Tampubolon, Gindo, Lee, Jinkook, Prescott, Carol A, Nazroo, James Y, Pendleton, Neil

“…The concept of frailty has been used in the clinical and research field for more than two decades. It is usually described as a clinical state of heightened…”
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Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE by Miller, Brendan, Kim, Su-Jeong, Mehta, Hemal H., Cao, Kevin, Kumagai, Hiroshi, Thumaty, Neehar, Leelaprachakul, Naphada, Braniff, Regina Gonzalez, Jiao, Henry, Vaughan, Joan, Diedrich, Jolene, Saghatelian, Alan, Arpawong, Thalida E., Crimmins, Eileen M., Ertekin-Taner, Nilüfer, Tubi, Meral A., Hare, Evan T., Braskie, Meredith N., Décarie-Spain, Léa, Kanoski, Scott E., Grodstein, Francine, Bennett, David A., Zhao, Lu, Toga, Arthur W., Wan, Junxiang, Yen, Kelvin, Cohen, Pinchas

“…Mitochondrial DNA variants have previously associated with disease, but the underlying mechanisms have been largely elusive. Here, we report that mitochondrial…”
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Longitudinal Examination of an Ethnic Paradox of Stress and Mental Health in Older Black and Latinx Adults by Arpawong, Thalida E., Sakuma, Kari-Lyn K., Espinoza, Lilia, Huh, Jimi

“…To explain the ethnic paradox of mental health in aging, we evaluated whether Black and Latinx older adults experience (1) fewer depressive symptoms (DepSx),…”
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ADHD genetic burden associates with older epigenetic age: mediating roles of education, behavioral and sociodemographic factors among older adults by Arpawong, Thalida E, Klopack, Eric T, Kim, Jung Ki, Crimmins, Eileen M

“…Shortened lifespans are associated with having Attention Deficit Hyperactivity Disorder (ADHD), which is likely mediated by related behavioral and…”
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Genetic variation in ALDH4A1 is associated with muscle health over the lifespan and across species by Villa, Osvaldo, Stuhr, Nicole L, Yen, Chia-An, Crimmins, Eileen M, Arpawong, Thalida Em, Curran, Sean P

“…The influence of genetic variation on the aging process, including the incidence and severity of age-related diseases, is complex. Here, we define the…”
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Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies by Miller, Brendan, Arpawong, Thalida E, Jiao, Henry, Kim, Su-Jeong, Yen, Kelvin, Mehta, Hemal H, Wan, Junxiang, Carpten, John C, Cohen, Pinchas

“…Mitochondrial genome-wide association studies identify mitochondrial single nucleotide polymorphisms (mtSNPs) that associate with disease or disease-related…”
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The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity by Kim, Su‐Jeong, Miller, Brendan, Mehta, Hemal H., Xiao, Jialin, Wan, Junxiang, Arpawong, Thalida E., Yen, Kelvin, Cohen, Pinchas

“…MOTS‐c is an exercise mimetic and improves insulin sensitivity in aged and diet‐induced obese mice. Although plasma markers are good markers for the metabolic…”
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Correction: Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE by Miller, Brendan, Kim, Su-Jeong, Mehta, Hemal H., Cao, Kevin, Kumagai, Hiroshi, Thumaty, Neehar, Leelaprachakul, Naphada, Braniff, Regina Gonzalez, Jiao, Henry, Vaughan, Joan, Diedrich, Jolene, Saghatelian, Alan, Arpawong, Thalida E., Crimmins, Eileen M., Ertekin-Taner, Nilüfer, Tubi, Meral A., Hare, Evan T., Braskie, Meredith N., Décarie-Spain, Léa, Kanoski, Scott E., Grodstein, Francine, Bennett, David A., Zhao, Lu, Toga, Arthur W., Wan, Junxiang, Yen, Kelvin, Cohen, Pinchas

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Hepatic WDR23 proteostasis mediates insulin homeostasis by regulating insulin-degrading enzyme capacity by Duangjan, Chatrawee, Arpawong, Thalida Em, Spatola, Brett N., Curran, Sean P.

“…Maintaining insulin homeostasis is critical for cellular and organismal metabolism. In the liver, insulin is degraded by the activity of the insulin-degrading…”
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Neuropsychological Test Performance and MRI Markers of Dementia Risk: Reducing Education Bias by Walter, Stefan, Dufouil, Carole, Gross, Alden L, Jones, Richard N, Mungas, Dan, Filshtein, Teresa J, Manly, Jennifer J, Arpawong, Thalida E, Glymour, M Maria

“…BACKGROUND:To use neuropsychological assessments for studying the underlying disease processes contributing to dementia, it is crucial that they correspond to…”
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Stressful life events and predictors of post-traumatic growth among high-risk early emerging adults by Arpawong, Thalida E., Rohrbach, Louise A., Milam, Joel E., Unger, Jennifer B., Land, Helen, Sun, Ping, Spruijt-Metz, Donna, Sussman, Steve

“…Stressful life events (SLEs) may elicit positive psychosocial change among youth, referred to as post-traumatic growth (PTG). We assessed types of SLEs…”
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Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom by Mekli, Krisztina, Phillips, Drystan F., Arpawong, Thalida E., Vanhoutte, Bram, Tampubolon, Gindo, Nazroo, James Y., Lee, Jinkook, Prescott, Carol A., Stevens, Adam, Pendleton, Neil

“…Unlike the diagnosed Major Depressive Disorder, depressive symptomatology in the general population has received less attention in genome-wide association scan…”
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Concurrent and predictive relationships between compulsive internet use and substance use: findings from vocational high school students in China and the USA by Sun, Ping, Johnson, Carl Anderson, Palmer, Paula, Arpawong, Thalida E, Unger, Jennifer B, Xie, Bin, Rohrbach, Louise A, Spruijt-Metz, Donna, Sussman, Steve

“…Compulsive Internet Use (CIU) has increasingly become an area of research among process addictions. Largely based on data from cross-sectional studies, a…”
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Post-traumatic growth, stressful life events, and relationships with substance use behaviors among alternative high school students: A prospective study by Arpawong, Thalida E., Sussman, Steve, Milam, Joel E., Unger, Jennifer B., Land, Helen, Sun, Ping, Rohrbach, Louise A.

“…A highly stressful life event (SLE) can elicit positive psychosocial growth, referred to as post-traumatic growth (PTG) among youth. We examined PTG and the…”
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A Polygenic Risk Score Associated with Measures of Depressive Symptoms Among Older Adults by Levine, Morgan E., Crimmins, Eileen M., Prescott, Carol A., Phillips, Drystan, Arpawong, Thalida E., Lee, Jinkook

“…It has been suggested that depression is a polygenic trait, arising from the influences of multiple loci with small individual effects. The aim of this study…”
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Effects of Recent Stress and Variation in the Serotonin Transporter Polymorphism (5-HTTLPR) on Depressive Symptoms: A Repeated-Measures Study of Adults Age 50 and Older by Arpawong, Thalida E., Lee, Jinkook, Phillips, Drystan F., Crimmins, Eileen M., Levine, Morgan E., Prescott, Carol A.

“…Depending on genetic sensitivity to it, stress may affect depressive symptomatology differentially. Applying the stress-diathesis hypothesis to older adults,…”
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