Search Results - "Arpag, Goker"

SSNA1 stabilizes dynamic microtubules and detects microtubule damage by Lawrence, Elizabeth J, Arpag, Goker, Arnaiz, Cayetana, Zanic, Marija

“…Sjögren's syndrome nuclear autoantigen-1 (SSNA1/NA14) is a microtubule-associated protein with important functions in cilia, dividing cells, and developing…”
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Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis by Snider, Chloe E, Willet, Alaina H, Chen, Jun-Song, Arpağ, Göker, Zanic, Marija, Gould, Kathleen L

“…Many eukaryotic cells divide by assembling and constricting an actin- and myosin-based contractile ring (CR) that is physically linked to the plasma membrane…”
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Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots by Trogden, Kathryn P, Lee, Justin, Bracey, Kai M, Ho, Kung-Hsien, McKinney, Hudson, Zhu, Xiaodong, Arpag, Goker, Folland, Thomas G, Osipovich, Anna B, Magnuson, Mark A, Zanic, Marija, Gu, Guoqiang, Holmes, William R, Kaverina, Irina

“…Heterogeneity of glucose-stimulated insulin secretion (GSIS) in pancreatic islets is physiologically important but poorly understood. Here, we utilize mouse…”
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Human CLASP2 specifically regulates microtubule catastrophe and rescue by Lawrence, Elizabeth J, Arpag, Göker, Norris, Stephen R, Zanic, Marija

“…Cytoplasmic linker-associated proteins (CLASPs) are microtubule-associated proteins essential for microtubule regulation in many cellular processes. However,…”
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Microtubule minus-end stability is dictated by the tubulin off-rate by Strothman, Claire, Farmer, Veronica, Arpağ, Göker, Rodgers, Nicole, Podolski, Marija, Norris, Stephen, Ohi, Ryoma, Zanic, Marija

“…Dynamic organization of microtubule minus ends is vital for the formation and maintenance of acentrosomal microtubule arrays. In vitro, both microtubule ends…”
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Dynamic Instability and Treadmilling Coexist for In Vitro Microtubules by Arpag, Goker, Zanic, Marija

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Microtubule Treadmilling Reconstituted with a Minimal-component in vitro System by Arpag, Goker, Lawrence, Elizabeth, Zanic, Marija

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SSNA1 stabilizes dynamic microtubules and detects microtubule damage by Lawrence, Elizabeth, Arpag, Goker, Arnaiz, Cayetana, Zanic, Marija

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XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end by Farmer, Veronica J., Arpag, Goker, Hall, Sarah L., Zanic, Marija

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Collective Effects of Xmap215, EB1, CLASP2, and MCAK Lead to Robust Microtubule Treadmilling by Arpag, Goker, Lawrence, Elizabeth J., Farmer, Veronica J., Hall, Sarah L., Zanic, Marija

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Efficient Tip Tracking and Analysis of EB1-Decorated Dynamic Microtubules from in Vitro Time-Lapse Images by Hwang, Wonmuk, Arpag, Goker, Farmer, Veronica J., Lawrence, Elizabeth, Zanic, Marija

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A Perspective on the Role of Myosins as Mechanosensors by Greenberg, Michael J., Arpağ, Göker, Tüzel, Erkan, Ostap, E. Michael

“…Cells are dynamic systems that generate and respond to forces over a range of spatial and temporal scales, spanning from single molecules to tissues…”
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Modeling Cargo Transport by Pairs of Kinesin-1 and -3 Motors by Arpag, Goker, Norris, Stephen, Verhey, Kristen, Hancock, William O., Tuzel, Erkan

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Collective effects of XMAP215, EB1, CLASP2, and MCAK lead to robust microtubule treadmilling by Arpağ, Göker, Lawrence, Elizabeth J., Farmer, Veronica J., Hall, Sarah L., Zanic, Marija

“…Microtubule network remodeling is essential for fundamental cellular processes including cell division, differentiation, and motility. Microtubules are active…”
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Force Generation by Membrane-Associated Myosin-I by Pyrpassopoulos, Serapion, Arpag, Goker, Feeser, Elizabeth A., Shuman, Henry, Tuzel, Erkan, Ostap, E. Michael

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XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end by Farmer, Veronica, Arpağ, Göker, Hall, Sarah L., Zanic, Marija

“…The GTP-tubulin cap is widely accepted to protect microtubules against catastrophe. The GTP-cap size is thought to increase with the microtubule growth rate,…”
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Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for In Vivo Function by Arpağ, Göker, Shastry, Shankar, Hancock, William O., Tüzel, Erkan

“…Intracellular cargo transport frequently involves multiple motor types, either having opposite directionality or having the same directionality but different…”
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Experimental and Computational Investigations into Cooperative Cargo Transport by Mixtures of Kinesins from Different Families by Arpag, Goker, Shastry, Shankar, Hancock, William O., Tuzel, Erkan

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Force Generation by Membrane-Associated Myosin-I by Pyrpassopoulos, Serapion, Arpağ, Göker, Feeser, Elizabeth A., Shuman, Henry, Tüzel, Erkan, Ostap, E. Michael

“…Vertebrate myosin-IC (Myo1c) is a type-1 myosin that links cell membranes to the cytoskeleton via its actin-binding motor domain and its phosphatidylinositol…”
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Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors by Arpağ, Göker, Norris, Stephen R., Mousavi, S. Iman, Soppina, Virupakshi, Verhey, Kristen J., Hancock, William O., Tüzel, Erkan

“…Intracellular cargo transport by kinesin family motor proteins is crucial for many cellular processes, particularly vesicle transport in axons and dendrites…”
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