Search Results - "Aros, Cody J"

Wnt signaling in lung development, regeneration, and disease progression by Aros, Cody J., Pantoja, Carla J., Gomperts, Brigitte N.

“…The respiratory tract is a vital, intricate system for several important biological processes including mucociliary clearance, airway conductance, and gas…”
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The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia by Fernando, Thilini R, Contreras, Jorge R, Zampini, Matteo, Rodriguez-Malave, Norma I, Alberti, Michael O, Anguiano, Jaime, Tran, Tiffany M, Palanichamy, Jayanth K, Gajeton, Jasmine, Ung, Nolan M, Aros, Cody J, Waters, Ella V, Casero, David, Basso, Giuseppe, Pigazzi, Martina, Rao, Dinesh S

“…Long non-coding RNAs (lncRNAs) play a variety of cellular roles, including regulation of transcription and translation, leading to alterations in gene…”
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Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma by Lee, Carolyn S, Bhaduri, Aparna, Mah, Angela, Johnson, Whitney L, Ungewickell, Alexander, Aros, Cody J, Nguyen, Christie B, Rios, Eon J, Siprashvili, Zurab, Straight, Aaron, Kim, Jinah, Aasi, Sumaira Z, Khavari, Paul A

“…Paul Khavari and colleagues identify recurrent mutations concentrated at an ultraviolet signature hotspot in the KNSTRN gene in 19% of cutaneous squamous cell…”
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Targeting PEA3 transcription factors to mitigate small cell lung cancer progression by Shia, David W., Choi, WooSuk, Vijayaraj, Preethi, Vuong, Valarie, Sandlin, Jenna M., Lu, Michelle M., Aziz, Adam, Marin, Caliope, Aros, Cody J., Sen, Chandani, Durra, Abdo, Lund, Andrew J., Purkayastha, Arunima, Rickabaugh, Tammy M., Graeber, Thomas G., Gomperts, Brigitte N.

“…Small cell lung cancer (SCLC) remains a lethal disease with a dismal overall survival rate of 6% despite promising responses to upfront combination…”
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High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis by Aros, Cody J., Paul, Manash K., Pantoja, Carla J., Bisht, Bharti, Meneses, Luisa K., Vijayaraj, Preethi, Sandlin, Jenna M., France, Bryan, Tse, Jonathan A., Chen, Michelle W., Shia, David W., Rickabaugh, Tammy M., Damoiseaux, Robert, Gomperts, Brigitte N.

“…Mechanisms underpinning airway epithelial homeostatic maintenance and ways to prevent its dysregulation remain elusive. Herein, we identify that β-catenin…”
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Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule by Vijayaraj, Preethi, Minasyan, Aspram, Durra, Abdo, Karumbayaram, Saravanan, Mehrabi, Mehrsa, Aros, Cody J., Ahadome, Sarah D., Shia, David W., Chung, Katherine, Sandlin, Jenna M., Darmawan, Kelly F., Bhatt, Kush V., Manze, Chase C., Paul, Manash K., Wilkinson, Dan C., Yan, Weihong, Clark, Amander T., Rickabaugh, Tammy M., Wallace, W. Dean, Graeber, Thomas G., Damoiseaux, Robert, Gomperts, Brigitte N.

“…Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are…”
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Indirect Immunofluorescence of Tissue Sections by Aros, Cody J

“…Immunofluorescence (IF) on tissue sections allows for the detection of protein species subcellular localization. IF studies further offer the ability to…”
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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition by Carraro, Gianni, Langerman, Justin, Sabri, Shan, Lorenzana, Zareeb, Purkayastha, Arunima, Zhang, Guangzhu, Konda, Bindu, Aros, Cody J., Calvert, Ben A., Szymaniak, Aleks, Wilson, Emily, Mulligan, Michael, Bhatt, Priyanka, Lu, Junjie, Vijayaraj, Preethi, Yao, Changfu, Shia, David W., Lund, Andrew J., Israely, Edo, Rickabaugh, Tammy M., Ernst, Jason, Mense, Martin, Randell, Scott H., Vladar, Eszter K., Ryan, Amy L., Plath, Kathrin, Mahoney, John E., Stripp, Barry R., Gomperts, Brigitte N.

“…Cystic fibrosis (CF) is a lethal autosomal recessive disorder that afflicts more than 70,000 people. People with CF experience multi-organ dysfunction…”
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Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging by Aros, Cody J., Vijayaraj, Preethi, Pantoja, Carla J., Bisht, Bharti, Meneses, Luisa K., Sandlin, Jenna M., Tse, Jonathan A., Chen, Michelle W., Purkayastha, Arunima, Shia, David W., Sucre, Jennifer M.S., Rickabaugh, Tammy M., Vladar, Eszter K., Paul, Manash K., Gomperts, Brigitte N.

“…Our understanding of dynamic interactions between airway basal stem cells (ABSCs) and their signaling niches in homeostasis, injury, and aging remains elusive…”
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Posttranslational modification of β-catenin is associated with pathogenic fibroblastic changes in bronchopulmonary dysplasia by Sucre, Jennifer M S, Vijayaraj, Preethi, Aros, Cody J, Wilkinson, Dan, Paul, Manash, Dunn, Bruce, Guttentag, Susan H, Gomperts, Brigitte N

“…Bronchopulmonary dysplasia (BPD) is a common complication of premature birth. The histopathology of BPD is characterized by an arrest of alveolarization with…”
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Cancer-Associated Long Noncoding RNA SMRT-2 Controls Epidermal Differentiation by Lee, Carolyn S., Mah, Angela, Aros, Cody J., Lopez-Pajares, Vanessa, Bhaduri, Aparna, Webster, Dan E., Kretz, Markus, Khavari, Paul A.

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Transcriptome sequencing in Sézary syndrome identifies Sézary cell and mycosis fungoides-associated lncRNAs and novel transcripts by Lee, Carolyn S., Ungewickell, Alexander, Bhaduri, Aparna, Qu, Kun, Webster, Dan E., Armstrong, Randall, Weng, Wen-Kai, Aros, Cody J., Mah, Angela, Chen, Richard O., Lin, Meihong, Sundram, Uma, Chang, Howard Y., Kretz, Markus, Kim, Youn H., Khavari, Paul A.

“…Sézary syndrome (SS) is an aggressive cutaneous T-cell lymphoma (CTCL) of unknown etiology in which malignant cells circulate in the peripheral blood. To…”
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