Search Results - "Arora, Anupa"

Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition by Pontecorvo, Michael J, Devous, Sr, Michael D, Navitsky, Michael, Lu, Ming, Salloway, Stephen, Schaerf, Frederick W, Jennings, Danna, Arora, Anupa K, McGeehan, Anne, Lim, Nathaniel C, Xiong, Hui, Joshi, Abhinay D, Siderowf, Andrew, Mintun, Mark A

“…The advent of tau-targeted positron emission tomography tracers such as flortaucipir (18F-AV-1451, also known as 18F-T807) have made it possible to investigate…”
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A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia by Pontecorvo, Michael J, Devous, Michael D, Kennedy, Ian, Navitsky, Michael, Lu, Ming, Galante, Nicholas, Salloway, Stephen, Doraiswamy, P Murali, Southekal, Sudeepti, Arora, Anupa K, McGeehan, Anne, Lim, Nathaniel C, Xiong, Hui, Truocchio, Stephen P, Joshi, Abhinay D, Shcherbinin, Sergey, Teske, Brian, Fleisher, Adam S, Mintun, Mark A

“…The advent of tau-targeted PET tracers such as flortaucipir (18F) (flortaucipir, also known as 18F-AV-1451 or 18F-T807) have made it possible to investigate…”
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Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes by Fleisher, Adam S, Pontecorvo, Michael J, Devous, Sr, Michael D, Lu, Ming, Arora, Anupa K, Truocchio, Stephen P, Aldea, Patricia, Flitter, Matthew, Locascio, Tricia, Devine, Marybeth, Siderowf, Andrew, Beach, Thomas G, Montine, Thomas J, Serrano, Geidy E, Curtis, Craig, Perrin, Allison, Salloway, Stephen, Daniel, Misty, Wellman, Charles, Joshi, Abhinay D, Irwin, David J, Lowe, Val J, Seeley, William W, Ikonomovic, Milos D, Masdeu, Joseph C, Kennedy, Ian, Harris, Thomas, Navitsky, Michael, Southekal, Sudeepti, Mintun, Mark A

“…Positron emission tomography (PET) may increase the diagnostic accuracy and confirm the underlying neuropathologic changes of Alzheimer disease (AD). To…”
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Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study by Clark, Christopher M, MD, Pontecorvo, Michael J, Dr, Beach, Thomas G, MD, Bedell, Barry J, MD, Coleman, R Edward, Prof, Doraiswamy, P Murali, Prof, Fleisher, Adam S, MD, Reiman, Eric M, Prof, Sabbagh, Marwan N, MD, Sadowsky, Carl H, Prof, Schneider, Julie A, MD, Arora, Anupa, MD, Carpenter, Alan P, PhD, Flitter, Matthew L, BA, Joshi, Abhinay D, MS, Krautkramer, Michael J, BS, Lu, Ming, MS, Mintun, Mark A, MD, Skovronsky, Daniel M, MD

“…Summary Background Results of previous studies have shown associations between PET imaging of amyloid plaques and amyloid-β pathology measured at autopsy…”
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Quantitation of PET signal as an adjunct to visual interpretation of florbetapir imaging by Pontecorvo, Michael J., Arora, Anupa K., Devine, Marybeth, Lu, Ming, Galante, Nick, Siderowf, Andrew, Devadanam, Catherine, Joshi, Abhinay D., Heun, Stephen L., Teske, Brian F., Truocchio, Stephen P., Krautkramer, Michael, Devous, Michael D., Mintun, Mark A.

“…Purpose This study examined the feasibility of using quantitation to augment interpretation of florbetapir PET amyloid imaging. Methods A total of 80 physician…”
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Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive Impairment and Alzheimer Disease: Results From 2 Phase III Clinical Trials by Lu, Ming, Pontecorvo, Michael J, Devous, Sr, Michael D, Arora, Anupa K, Galante, Nicholas, McGeehan, Anne, Devadanam, Catherine, Salloway, Stephen P, Doraiswamy, P Murali, Curtis, Craig, Truocchio, Stephen P, Flitter, Matthew, Locascio, Tricia, Devine, Marybeth, Zimmer, Jennifer A, Fleisher, Adam S, Mintun, Mark A

“…Flortaucipir positron emission tomography (PET) scans, rated with a novel, US Food and Drug Administration-approved, clinically applicable visual…”
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Potential Impact of Amyloid Imaging on Diagnosis and Intended Management in Patients With Progressive Cognitive Decline by GRUNDMAN, Michael, PONTECORVO, Michael J, AGBULOS, Abigail, FLITTER, Matthew L, KRAUTKRAMER, Michael J, SARSOUR, Khaled, SKOVRONSKY, Daniel M, MINTUN, Mark A, SALLOWAY, Stephen P, MURALI DORAISWAMY, P, FLEISHER, Adam S, SADOWSKY, Carl H, NAIR, Anil K, SIDEROWF, Andrew, MING LU, ARORA, Anupa K

“…Florbetapir F18 has been approved by the Food and Drug Administration for in vivo assessment of amyloid pathology in patients undergoing evaluation for…”
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Clinical and cortical decline in the aphasic variant of Alzheimer's disease by Rogalski, Emily Joy, Sridhar, Jaiashre, Martersteck, Adam, Rader, Benjamin, Cobia, Derin, Arora, Anupa K., Fought, Angela J., Bigio, Eileen H., Weintraub, Sandra, Mesulam, Marek-Marsel, Rademaker, Alfred

“…Primary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation. Longitudinal quantitation of atrophy and…”
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Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer’s disease pathology: a clinicopathological study by Pontecorvo, Michael J., Keene, C. Dirk, Beach, Thomas G., Montine, Thomas J., Arora, Anupa K., Devous, Michael D., Navitsky, Michael, Kennedy, Ian, Joshi, Abhinay D., Lu, Ming, Serrano, Geidy E., Sue, Lucia I., Intorcia, Anthony J., Rose, Shannon E., Wilson, Angela, Hellstern, Leanne, Coleman, Natalie, Flitter, Matthew, Aldea, Patricia, Fleisher, Adam S., Mintun, Mark A., Siderowf, Andrew

“…Background The objective of this study was to make a quantitative comparison of flortaucipir PET retention with pathological tau and β-amyloid across a range…”
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Effect of Amyloid Imaging on the Diagnosis and Management of Patients with Cognitive Decline: Impact of Appropriate Use Criteria by Grundman, Michael, Johnson, Keith A, Lu, Ming, Siderowf, Andrew, Dell'Agnello, Grazia, Arora, Anupa K, Skovronsky, Daniel M, Mintun, Mark A, Pontecorvo, Michael J

“…Published appropriate use criteria (AUC) describe patients for whom amyloid positron emission tomography (PET) might be most useful. This study compared the…”
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Tau as a diagnostic instrument in clinical trials to predict amyloid in Alzheimer's disease by Shcherbinin, Sergey, Morris, Amanda, Higgins, Ixavier A, Tunali, Ilke, Lu, Ming, Deveau, Carmen, Southekal, Sudeepti, Kotari, Vikas, Evans, Cynthia D, Arora, Anupa K, Collins, Emily C, Pontecorvo, Michael, Mintun, Mark A, Sims, John R

“…Alzheimer's disease (AD) is characterized by the presence of both amyloid and tau pathology. In vivo diagnosis can be made with amyloid and tau positron…”
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Performance characteristics of amyloid PET with florbetapir F 18 in patients with alzheimer's disease and cognitively normal subjects by Joshi, Abhinay D, Pontecorvo, Michael J, Clark, Chrisopher M, Carpenter, Alan P, Jennings, Danna L, Sadowsky, Carl H, Adler, Lee P, Kovnat, Karel D, Seibyl, John P, Arora, Anupa, Saha, Krishnendu, Burns, Jason D, Lowrey, Mark J, Mintun, Mark A, Skovronsky, Daniel M

“…The objectives of this study were to examine the effective dose range and the test-retest reliability of florbetapir F 18 using, first, visual assessment by…”
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A comparison of two novel visual read‐based methods for high tau identification from flortaucipir‐PET by Iaccarino, Leonardo, Tunali, Ilke, Kim, Min Jung, Lu, Ming, DiFabbio, Kelly, Kowaleski, Stacey, Ducker, Courtney, Patel, Sneha, Arora, Anupa, Southekal, Sudeepti, Kotari, Vikas, Shcherbinin, Sergey, Pontecorvo, Michael J.

“…Background To compare the performances of two novel visual read‐based methods for flortaucipir‐PET in patients with Alzheimer’s Disease (AD) to identify high…”
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Regional tau PET patterns predict prospective domain‐specific cognitive decline in Alzheimer’s Disease by Malpetti, Maura, Iaccarino, Leonardo, Tanner, Jeremy A, Mundada, Nidhi S., Cobigo, Yann, Arora, Anupa, Pontecorvo, Michael J., La Joie, Renaud, Rabinovici, Gil D.

“…Background Tau‐PET binding patterns are heterogenous, with regional binding showing strong cross‐sectional correlations with domain‐specific cognitive…”
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Comparison of Expert Reads vs. Local Clinical Reads of Amyloid PET Scans in IDEAS by Windon, Charles, Zeltzer, Ehud, Hanna, Lucy, Carrillo, Maria C., Iaccarino, Leonardo, La Joie, Renaud, March, Andrew, Mejía, Jhony Alejadro, Mundada, Nidhi, Arora, Anupa, Bullich, Santiago, Sherwin, Paul, Siegel, Barry A, Gatsonis, Constantine, Rabinovici, Gil D.

“…Background Amyloid‐directed therapies will increase the clinical use of amyloid PET. IDEAS captured >17,000 clinical scan interpretations from local…”
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Comparison of Expert Reads vs. Local Clinical Reads of Amyloid PET Scans in IDEAS by Windon, Charles, Zeltzer, Ehud, Hanna, Lucy, Carrillo, Maria C., Iaccarino, Leonardo, La Joie, Renaud, March, Andrew, Mejía, Jhony Alejadro, Mundada, Nidhi, Arora, Anupa, Bullich, Santiago, Sherwin, Paul, Siegel, Barry A, Gatsonis, Constantine, Rabinovici, Gil D.

“…Background Amyloid‐directed therapies will increase the clinical use of amyloid PET. IDEAS captured >17,000 clinical scan interpretations from local…”
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Evaluation of a visual read method for flortaucipir PET Scans by Arora, Anupa, Pontecorvo, Michael, Mintun, Mark, Fleisher, Adam, Devous, Michael, Lu, Ming, Galante, Nicholas, Stevenson, Patricia, Flitter, Matthew, Truocchio, Stephen

“…Objectives: To evaluate a clinically applicable visual read method for flortaucipir PET scans. Methods: Five imaging physicians were trained in-person using a…”
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Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment: The Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Study by Boccardi, Marina, Altomare, Daniele, Ferrari, Clarissa, Festari, Cristina, Guerra, Ugo Paolo, Paghera, Barbara, Pizzocaro, Claudio, Lussignoli, Giulia, Geroldi, Cristina, Zanetti, Orazio, Cotelli, Maria Sofia, Turla, Marinella, Borroni, Barbara, Rozzini, Luca, Mirabile, Dario, Defanti, Carlo, Gennuso, Michele, Prelle, Alessandro, Gentile, Simona, Morandi, Alessandro, Vollaro, Stefano, Volta, Giorgio Dalla, Bianchetti, Angelo, Conti, Marta Zaffira, Cappuccio, Melania, Carbone, Pasqualina, Bellandi, Daniele, Abruzzi, Luciano, Bettoni, Luigi, Villani, Daniele, Raimondi, Maria Clara, Lanari, Alessia, Ciccone, Alfonso, Facchi, Emanuela, Di Fazio, Ignazio, Rozzini, Renzo, Boffelli, Stefano, Manzoni, Laura, Salvi, Giovanni Pietro, Cavaliere, Sabina, Belotti, Gloria, Avanzi, Stefano, Pasqualetti, Patrizio, Muscio, Cristina, Padovani, Alessandro, Frisoni, Giovanni B

“…Cerebral amyloidosis is a key abnormality in Alzheimer disease (AD) and can be detected in vivo with positron emission tomography (PET) ligands. Although…”
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DT‐01‐05: TEMPORAL LOBE QUANTITATION OF FLORTAUCIPIR PET IMAGES MAY IMPROVE DETECTION OF INTERMEDIATE NEUROFIBRILLARY TANGLE PATHOLOGY IN AUTOPSY‐VALIDATED CASES by Southekal, Sudeepti, Kotari, Vikas, Devous, Michael D., Navitsky, Michael, Kennedy, Ian, Beach, Thomas G., Montine, Thomas J., Arora, Anupa, Flitter, Matthew L., Fleisher, Adam S., Pontecorvo, Michael J., Mintun, Mark A.

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TEMPORAL LOBE QUANTITATION OF FLORTAUCIPIR PET IMAGES MAY IMPROVE DETECTION OF INTERMEDIATE NEUROFIBRILLARY TANGLE PATHOLOGY IN AUTOPSY-VALIDATED CASES by Southekal, Sudeepti, Kotari, Vikas, Devous, Michael D., Navitsky, Michael, Kennedy, Ian, Beach, Thomas G., Montine, Thomas J., Arora, Anupa, Flitter, Matthew L., Fleisher, Adam S., Pontecorvo, Michael J., Mintun, Mark A.

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