Search Results - "Aroeira, Luiz Stark"
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The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response
Published in Laboratory investigation (01-07-2013)“…Connective tissue growth factor (CTGF/CCN2) is a matricellular protein susceptible to proteolytic degradation. CCN2 levels have been suggested as a potential…”
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TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2
Published in Mediators of Inflammation (01-01-2015)“…The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal…”
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TWEAK promotes peritoneal inflammation
Published in PloS one (05-03-2014)“…Peritoneal dialysis (PD) is complicated by peritonitis episodes that cause loss of mesothelium and eventually sclerosing peritonitis. An improved understanding…”
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A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury
Published in PloS one (13-08-2009)“…Inflammation may lead to tissue injury. We have studied the modulation of inflammatory milieu-induced tissue injury, as exemplified by the mesothelium…”
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Mouse B-1 cell-derived mononuclear phagocyte, a novel cellular component of acute non-specific inflammatory exudate
Published in International immunology (01-09-2001)“…At least three B cell subsets, B-1a, B-1b and B-2, or conventional B cells are present in the mouse periphery. Here we demonstrate that B-1 cells spontaneously…”
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CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF-κB
Published in Journal of the American Society of Nephrology (01-07-2009)“…Connective tissue growth factor (CTGF) is an important profibrotic factor in kidney diseases. Blockade of endogenous CTGF ameliorates experimental renal damage…”
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Treatment with Natalizumab in Relapsing–Remitting Multiple Sclerosis Patients Induces Changes in Inflammatory Mechanism
Published in Journal of clinical immunology (01-08-2011)“…Natalizumab is a widely accepted drug for the relapsing–remitting subtype of multiple sclerosis (RRMS). The present longitudinal exploratory study in RRMS…”
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Citrin deficiency: Early severe cases in a European country
Published in Clinics and research in hepatology and gastroenterology (01-07-2021)Get full text
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Pharmacological modulation of peritoneal injury induced by dialysis fluids: is it an option?
Published in Nephrology, dialysis, transplantation (01-02-2012)Get full text
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TCR vaccination in aluminum adjuvant protects against autoimmune encephalomyelitis
Published in Clinical Immunology (01-06-2006)“…Experimental Allergic Encephalomyelitis (EAE) is a neuroinflammatory, autoimmune disorder in which myelin-reactive Th1 T cells with a restricted TCRVβ…”
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Evidence for B cell participation in the in vitro and in vivo maintenance of in vivo staphylococcal enterotoxin B-induced T cell anergy
Published in International immunology (01-01-1997)“…The mechanisms involved in the maintenance of staphylococcal enterotoxin B (SEB)-induced T cell anergy are poorly understood. Here, we demonstrate that CD4+ T…”
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Age-dependent changes in the response to staphylococcal enterotoxin B
Published in International immunology (01-10-1994)“…In the present study we investigated the response of old mice to staphylococcal enterotoxin B (SEB) immunization. Old mice were susceptible to lethal toxic…”
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Anti‐Vβ8 antibodies induce and maintain staphylococcal enterotoxin B‐triggered Vβ8+ T cell anergy
Published in European journal of immunology (01-02-1999)“…The mechanism involved in the maintenance of staphylococcal enterotoxin B (SEB)‐induced T cell anergy is poorly understood. We demonstrated earlier that B…”
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TH1/TH2 Cytokine profile in relapsing-remitting multiple sclerosis patients treated with Glatiramer acetate or Natalizumab
Published in BMC neurology (18-09-2012)“…The balance between T helper cells Th2- and Th1-related cytokines plays a key role in multiple sclerosis (MS). A shift from a Th1 towards a Th2 cytokine…”
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H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity
Published in Blood (12-05-2011)“…The small guanine nucleotide binding proteins of the Ras family, including in mammals the highly homologous H-ras, N-ras, and K-ras isoforms, are rapidly…”
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A natural anti-T-cell receptor monoclonal antibody protects against experimental autoimmune encephalomyelitis
Published in Journal of neuroimmunology (01-05-2011)“…Abstract The therapeutic potential of natural anti-T-cell receptor (TCR) antibodies is largely unknown. We investigated whether passive administration of…”
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The role of IL‐4 in the staphylococcal enterotoxin B‐triggered immune response: increased susceptibility to shock and deletion of CD8Vβ8+ T cells in IL‐4 knockout mice
Published in European journal of immunology (01-04-1999)“…Administration of superantigens in vivo triggers responding T cells into clonal expansion and subsequent activation of the programmed cell death pathway, as…”
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CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB
Published in Journal of the American Society of Nephrology (01-07-2009)“…Connective tissue growth factor (CTGF) is an important profibrotic factor in kidney diseases. Blockade of endogenous CTGF ameliorates experimental renal damage…”
Get full text
Journal Article