Search Results - "Aroeira, Luiz S"
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Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production
Published in PloS one (03-10-2014)“…Fibrosis is a significant health problem associated with a chronic inflammatory reaction. The precise mechanisms involved in the fibrotic process are still…”
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Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis
Published in Nephrology, dialysis, transplantation (01-09-2011)“…Background. Depending on the cytokine microenvironment, macrophages (M ) can adopt a proinflammatory (M1) or a profibrotic (M2) phenotype characterized by the…”
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BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure
Published in Nephrology, dialysis, transplantation (01-04-2010)“…Background. During peritoneal dialysis (PD), mesothelial cells (MC) undergo an epithelial-to-mesenchymal transition (EMT), and this process is associated with…”
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Mesenchymal Conversion of Mesothelial Cells as a Mechanism Responsible for High Solute Transport Rate in Peritoneal Dialysis: Role of Vascular Endothelial Growth Factor
Published in American journal of kidney diseases (01-11-2005)“…Background: During peritoneal dialysis (PD), the peritoneum is exposed to bioincompatible dialysis fluids that cause epithelial-to-mesenchymal transition of…”
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Immunohistochemical characterization of fibroblast subpopulations in normal peritoneal tissue and in peritoneal dialysis-induced fibrosis
Published in Virchows Archiv : an international journal of pathology (01-03-2004)“…Peritoneal fibrosis is one of the most common morphological changes observed in continuous ambulatory peritoneal dialysis (CAPD) patients. Both resident…”
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EX VIVO ANALYSIS OF DIALYSIS EFFLUENT-DERIVED MESOTHELIAL CELLS AS AN APPROACH TO UNVEILING THE MECHANISM OF PERITONEAL MEMBRANE FAILURE
Published in Peritoneal dialysis international (01-01-2006)“…Unidad de Biología Molecular, 1 Hospital Universitario de la Princesa, Madrid; Departamento de Patología, 2 Hospital Universitario de Guadalajara, Guadalajara;…”
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IL-17A is a novel player in dialysis-induced peritoneal damage
Published in Kidney international (01-08-2014)“…The classical view of the immune system has changed by the discovery of novel T-helper (Th) subsets, including Th17 (IL-17A-producing cells). IL-17A…”
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Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients : Pathologic significance and potential therapeutic interventions
Published in Journal of the American Society of Nephrology (01-07-2007)“…Peritoneal dialysis (PD) is a form of renal replacement and is based on the use of the peritoneum as a semipermeable membrane across which ultrafiltration and…”
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Sensitive and non-invasive method for the in vivo analysis of membrane permeability in small animals
Published in Laboratory investigation (01-09-2017)“…Tissue membranes are boundaries that isolate organs or cavities in the body. These semi-permeable membranes are responsible for passive protection that acts…”
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B cells modulate T cells so as to favour T helper type 1 and CD8+ T‐cell responses in the acute phase of Trypanosoma cruzi infection
Published in Immunology (01-12-2007)“…Summary In this study, we have evaluated the production of pro‐ and anti‐inflammatory cytokines and the formation of central and effector memory T cells in…”
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Cyclooxygenase-2 Mediates Dialysate-Induced Alterations of the Peritoneal Membrane
Published in Journal of the American Society of Nephrology (01-03-2009)“…During peritoneal dialysis (PD), exposure of the peritoneal membrane to nonphysiologic solutions causes inflammation, ultimately leading to altered structure…”
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Influence of Bicarbonate/Low-GDP Peritoneal Dialysis Fluid (Bicavera) on In Vitro and Ex Vivo Epithelial-to-Mesenchymal Transition of Mesothelial Cells
Published in Peritoneal dialysis international (01-05-2012)“…Peritoneal membrane damage induced by peritoneal dialysis (PD) is largely associated with epithelial-to-mesenchymal transition (EMT) of mesothelial cells…”
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CHARACTERIZATION OF EPITHELIAL-TO-MESENCHYMAL TRANSITION OF MESOTHELIAL CELLS IN A MOUSE MODEL OF CHRONIC PERITONEAL EXPOSURE TO HIGH GLUCOSE DIALYSATE
Published in Peritoneal dialysis international (01-11-2008)“…Animal models of peritoneal dialysis fluid (PDF) exposure are key tools in the study of mechanisms involved in alterations of the peritoneal membrane and in…”
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TH1/TH2 Cytokine profile in relapsing-remitting multiple sclerosis patients treated with Glatiramer acetate or Natalizumab
Published in BMC neurology (18-09-2012)“…The balance between T helper cells Th2- and Th1-related cytokines plays a key role in multiple sclerosis (MS). A shift from a Th1 towards a Th2 cytokine…”
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B cells modulate T cells so as to favour T helper type 1 and CD8 super(+) T-cell responses in the acute phase of Trypanosoma cruzi infection
Published in Immunology (01-12-2007)“…In this study, we have evaluated the production of pro- and anti-inflammatory cytokines and the formation of central and effector memory T cells in mice…”
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Paricalcitol Reduces Peritoneal Fibrosis in Mice through the Activation of Regulatory T Cells and Reduction in IL-17 Production: e108477
Published in PloS one (01-10-2014)“…Fibrosis is a significant health problem associated with a chronic inflammatory reaction. The precise mechanisms involved in the fibrotic process are still…”
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Anti-γδ T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice
Published in Immunology letters (01-12-1995)“…The oral administration of antigens is one of the means of inducing tolerance in adult mammals. In this report, the role of γδ T cells in the induction and…”
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Absence of peripheral clonal deletion and anergy in immune responses of T cell-reconstituted athymic mice
Published in European journal of immunology (01-03-1994)“…Superantigens induce clonal deletion of reactive T cells in the thymus and clonal deletion and anergy in the periphery of euthymic mice. In this report we have…”
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