Search Results - "Arnott, David"

NLRP3 recruitment by NLRC4 during Salmonella infection by Qu, Yan, Misaghi, Shahram, Newton, Kim, Maltzman, Allie, Izrael-Tomasevic, Anita, Arnott, David, Dixit, Vishva M

“…NLRC4 and NLRP3, of the NOD-like receptor (NLR) family of intracellular proteins, are expressed in innate immune cells and are thought to nucleate distinct…”
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Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation by Raisner, Ryan, Kharbanda, Samir, Jin, Lingyan, Jeng, Edwin, Chan, Emily, Merchant, Mark, Haverty, Peter M., Bainer, Russell, Cheung, Tommy, Arnott, David, Flynn, E. Megan, Romero, F. Anthony, Magnuson, Steven, Gascoigne, Karen E.

“…Acetylation of histone H3 at lysine 27 is a well-defined marker of enhancer activity. However, the functional impact of this modification at enhancers is…”
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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure by Guler, Gulfem Dilek, Tindell, Charles Albert, Pitti, Robert, Wilson, Catherine, Nichols, Katrina, KaiWai Cheung, Tommy, Kim, Hyo-Jin, Wongchenko, Matthew, Yan, Yibing, Haley, Benjamin, Cuellar, Trinna, Webster, Joshua, Alag, Navneet, Hegde, Ganapati, Jackson, Erica, Nance, Tracy Leah, Giresi, Paul Garrett, Chen, Kuan-Bei, Liu, Jinfeng, Jhunjhunwala, Suchit, Settleman, Jeff, Stephan, Jean-Philippe, Arnott, David, Classon, Marie

“…Maintenance of phenotypic heterogeneity within cell populations is an evolutionarily conserved mechanism that underlies population survival upon stressful…”
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Phosphorylation of NLRC4 is critical for inflammasome activation by Qu, Yan, Misaghi, Shahram, Izrael-Tomasevic, Anita, Newton, Kim, Gilmour, Laurie L., Lamkanfi, Mohamed, Louie, Salina, Kayagaki, Nobuhiko, Liu, Jinfeng, Kömüves, László, Cupp, James E., Arnott, David, Monack, Denise, Dixit, Vishva M.

“…Phosphorylation of the NOD-like receptor NLRC4 is essential for activation of the NLRC4 inflammasome complex in response to bacterial stimuli. NLRC4…”
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Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method[S] by Maile, Tobias M., Izrael-Tomasevic, Anita, Cheung, Tommy, Guler, Gulfem D., Tindell, Charles, Masselot, Alexandre, Liang, Jun, Zhao, Feng, Trojer, Patrick, Classon, Marie, Arnott, David

“…Mass spectrometry is a powerful alternative to antibody-based methods for the analysis of histone post-translational modifications (marks). A key development…”
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A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine by Leadem, Benjamin R, Kagiampakis, Ioannis, Wilson, Catherine, Cheung, Tommy K, Arnott, David, Trojer, Patrick, Classon, Marie, Easwaran, Hariharan, Baylin, Stephen B

“…The H3K4 demethylase is amplified and overexpressed in luminal breast cancer, suggesting it might constitute a potential cancer therapy target. Here, we…”
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Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer by Gnad, Florian, Doll, Sophia, Manning, Gerard, Arnott, David, Zhang, Zemin

“…Many cancer cells show distorted epigenetic landscapes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors, allowing the discovery of somatic…”
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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition by Egan, Brian, Yuan, Chih-Chi, Craske, Madeleine Lisa, Labhart, Paul, Guler, Gulfem D, Arnott, David, Maile, Tobias M, Busby, Jennifer, Henry, Chisato, Kelly, Theresa K, Tindell, Charles A, Jhunjhunwala, Suchit, Zhao, Feng, Hatton, Charlie, Bryant, Barbara M, Classon, Marie, Trojer, Patrick

“…Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in inferring the roles of histone post-translational modifications in the…”
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Identification of longitudinally dynamic biomarkers in Alzheimer's disease cerebrospinal fluid by targeted proteomics by Wildsmith, Kristin R, Schauer, Stephen P, Smith, Ashley M, Arnott, David, Zhu, Yuda, Haznedar, Joshua, Kaur, Surinder, Mathews, W Rodney, Honigberg, Lee A

“…Alzheimer's disease (AD) is the leading cause of dementia affecting greater than 26 million people worldwide. Although cerebrospinal fluid (CSF) levels of…”
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Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1 by Misaghi, Shahram, Ottosen, Søren, Izrael-Tomasevic, Anita, Arnott, David, Lamkanfi, Mohamed, Lee, James, Liu, Jinfeng, O'Rourke, Karen, Dixit, Vishva M., Wilson, Angus C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation by de Almeida Nagata, Denise E., Chiang, Eugene Y., Jhunjhunwala, Suchit, Caplazi, Patrick, Arumugam, Vidhyalakshmi, Modrusan, Zora, Chan, Emily, Merchant, Mark, Jin, Lingyan, Arnott, David, Romero, F. Anthony, Magnuson, Steven, Gascoigne, Karen E., Grogan, Jane L.

“…Myeloid-derived suppressor cells (MDSCs) are found in most cancer malignancies and support tumorigenesis by suppressing immunity and promoting tumor growth…”
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Preparation of Distinct Ubiquitin Chain Reagents of High Purity and Yield by Dong, Ken C., Helgason, Elizabeth, Yu, Christine, Phu, Lilian, Arnott, David P., Bosanac, Ivan, Compaan, Deanne M., Huang, Oscar W., Fedorova, Anna V., Kirkpatrick, Donald S., Hymowitz, Sarah G., Dueber, Erin C.

“…The complexity of protein ubiquitination signals derives largely from the variety of polyubiquitin linkage types that can modify a target protein, each…”
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Glycan Shifting on Hepatitis C Virus (HCV) E2 Glycoprotein Is a Mechanism for Escape from Broadly Neutralizing Antibodies by Pantua, Homer, Diao, Jingyu, Ultsch, Mark, Hazen, Meredith, Mathieu, Mary, McCutcheon, Krista, Takeda, Kentaro, Date, Shailesh, Cheung, Tommy K., Phung, Qui, Hass, Phil, Arnott, David, Hongo, Jo-Anne, Matthews, David J., Brown, Alex, Patel, Arvind H., Kelley, Robert F., Eigenbrot, Charles, Kapadia, Sharookh B.

“…Hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma. Glycan shielding has been proposed to be a mechanism by which…”
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Trust - current thinking and future research by Arnott, David C

“…Purpose - The primary purpose of this article is to introduce the special issue on trust in marketing and the selected papers. However, it has a secondary…”
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ubiquitin ligase COP1 is a critical negative regulator of p53 by Dornan, D, Wertz, I, Shimizu, H, Arnott, D, Frantz, G.D, Dowd, P, O'Rourke, K, Koeppen, H, Dixit, V.M

“…COP1 (constitutively photomorphogenic 1) is a RING-finger-containing protein that functions to repress plant photomorphogenesis, the light-mediated programme…”
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The anchoring effect in business intelligence supported decision-making by Ni, Feng, Arnott, David, Gao, Shijia

“…This article reports on a study that is part of a larger project on how Business intelligence (BI) can effectively support a range of decisions made by…”
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Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals by Phu, Lilian, Izrael-Tomasevic, Anita, Matsumoto, Marissa L., Bustos, Daisy, Dynek, Jasmin N., Fedorova, Anna V., Bakalarski, Corey E., Arnott, David, Deshayes, Kurt, Dixit, Vishva M., Kelley, Robert F., Vucic, Domagoj, Kirkpatrick, Donald S.

“…Ubiquitinated substrates can be recruited to macromolecular complexes through interactions between their covalently bound ubiquitin (Ub) signals and Ub…”
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Mass Spectrometric Contributions to the Practice of Phosphorylation Site Mapping through 2003 by Loyet, Kelly M., Stults, John T., Arnott, David

“…Reversible phosphorylation of proteins is among the most important post-translational modifications, and elucidation of sites of phosphorylation is essential…”
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Research on trust: a bibliography and brief bibliometric analysis of the special issue submissions by Arnott, David C

“…Purpose - The primary purpose of this bibliography is to provide a compilation of trust-related articles from the disparate fields in which trust has been…”
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Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells by Sun, Yuting, Daemen, Anneleen, Hatzivassiliou, Georgia, Arnott, David, Wilson, Catherine, Zhuang, Guanglei, Gao, Min, Liu, Peter, Boudreau, Aaron, Johnson, Leisa, Settleman, Jeff

“…Accumulating preclinical and clinical evidence implicates epithelial-mesenchymal transition (EMT) in acquired resistance to anticancer drugs; however,…”
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