Search Results - "Arnone, MR"

Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-[kappa]B signaling by degrading TRAF2-associated cIAP1 in cancer cells by Mitsuuchi, Y, Benetatos, Ca, Deng, Y, Haimowitz, T, Beck, Sc, Arnone, Mr, Kapoor, Gs, Seipel, Me, Chunduru, Sk, Mckinlay, Ma, Begley, Cg, Condon, Sm

“…The inhibitor of apoptosis (IAP) proteins have pivotal roles in cell proliferation and differentiation, and antagonizing IAPs in certain cancer cell lines…”
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Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases by Markwalder, Jay A, Arnone, Marc R, Benfield, Pamela A, Boisclair, Michael, Burton, Catherine R, Chang, Chong-Hwan, Cox, Sarah S, Czerniak, Philip M, Dean, Charity L, Doleniak, Deborah, Grafstrom, Robert, Harrison, Barbara A, Kaltenbach, Robert F, Nugiel, David A, Rossi, Karen A, Sherk, Susan R, Sisk, Lisa M, Stouten, Pieter, Trainor, George L, Worland, Peter, Seitz, Steven P

“…Using a high-throughput screening strategy, a series of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-ones was identified that inhibit the cyclin-dependent…”
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Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-κB signaling by degrading TRAF2-associated cIAP1 in cancer cells by Mitsuuchi, Y, Benetatos, CA, Deng, Y, Haimowitz, T, Beck, SC, Arnone, MR, Kapoor, GS, Seipel, ME, Chunduru, SK, McKinlay, MA, Begley, CG, Condon, SM

“…The inhibitor of apoptosis (IAP) proteins have pivotal roles in cell proliferation and differentiation, and antagonizing IAPs in certain cancer cell lines…”
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Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay by Snyder, Ronald D, Arnone, Marc R

“…Clastogenicity is frequently observed following treatment of mammalian cells with new chemical entities. This clastogenicity, unless proven otherwise, is…”
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