Search Results - "Arnold, Malcolm"
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Grapefruit-medication interactions: forbidden fruit or avoidable consequences?
Published in Canadian Medical Association journal (CMAJ) (05-03-2013)“…Although some pharmacokinetic studies have tested a higher than usual amount of grapefruit juice to determine the maximum effect, this should not be…”
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2
Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-08-2010)“…Our recent study demonstrated that Rac1 and NADPH oxidase activation contributes to cardiomyocyte apoptosis in short-term diabetes. This study was undertaken…”
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3
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
Published in The New England journal of medicine (13-04-2006)“…In epidemiologic studies, the plasma total homocysteine level has been found to be a risk factor for cardiovascular disease. In the HOPE-2 trial of high-risk…”
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4
Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia
Published in Diabetes (New York, N.Y.) (01-10-2009)“…Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia E. Shen 1 , 2 , Yanwen Li 3 , Ying Li 1 , 2 , Limei Shan 1 , 2 , Huaqing Zhu 1 , 2 , Qingping…”
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5
Prostate cancer, version 2.2014
Published in Journal of the National Comprehensive Cancer Network (01-05-2014)“…Prostate cancer has surpassed lung cancer as the most common cancer in men in the United States. The NCCN Guidelines for Prostate Cancer provide…”
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6
Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure
Published in The New England journal of medicine (19-06-2008)“…In this clinical trial involving patients with atrial fibrillation and congestive heart failure, rhythm control (to maintain sinus rhythm) and rate control (to…”
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7
Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes
Published in Diabetes (New York, N.Y.) (01-11-2011)“…Recently we have shown that calpain-1 activation contributes to cardiomyocyte apoptosis induced by hyperglycemia. This study was undertaken to investigate…”
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8
An optically stimulated luminescence dosimeter for measuring patient exposure from imaging guidance procedures
Published in Physics in medicine & biology (07-09-2013)“…There is a growing interest in patient exposure resulting from an x-ray imaging procedure used in image-guided radiation therapy. This study explores a…”
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9
What matters to patients with heart failure? The influence of non-health-related goals on patient adherence to self-care management
Published in Patient education and counseling (01-08-2015)“…Highlights • Patients valued autonomy and social relationships as much as physical health. • Importance attributed to health goals did not predict self-care…”
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Prostate cancer, Version 3.2012: featured updates to the NCCN guidelines
Published in Journal of the National Comprehensive Cancer Network (01-09-2012)“…The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer provide multidisciplinary recommendations for the clinical management…”
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Prognostic implications of left ventricular mass and geometry following myocardial infarction: the VALIANT (VALsartan In Acute myocardial iNfarcTion) Echocardiographic Study
Published in JACC. Cardiovascular imaging (01-09-2008)“…This study sought to understand prognostic implications of increased baseline left ventricular (LV) mass and geometric patterns in a high risk acute myocardial…”
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12
Recombinant Human Annexin A5 Inhibits Proinflammatory Response and Improves Cardiac Function and Survival in Mice With Endotoxemia
Published in Critical care medicine (01-01-2014)“…OBJECTIVES:Annexin A5 is a 35-kDa protein with high affinity binding to negatively charged phospholipids. However, its effects on sepsis are not known. Our aim…”
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13
Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial
Published in The Lancet (British edition) (23-06-2007)“…Summary Background Diastolic dysfunction might represent an important pathophysiological intermediate between hypertension and heart failure. Our aim was to…”
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14
Aortic Diameter, Wall Stiffness, and Wave Reflection in Systolic Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-01-2008)“…Systolic hypertension is associated with increased pulse pressure (PP) and increased risk for adverse cardiovascular outcomes. However the pathogenesis of…”
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15
Reducing radiation exposure to patients from kV-CBCT imaging
Published in Radiotherapy and oncology (01-12-2010)“…Abstract Background and purpose This study explores methods to reduce dose due to kV-CBCT imaging for patients undergoing radiation therapy. Material and…”
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16
A study on adaptive IMRT treatment planning using kV cone-beam CT
Published in Radiotherapy and oncology (01-10-2007)“…Abstract Background and purpose Changes in tumor size during the course of radiotherapy warrant performing adaptive radiotherapy (ART). This work investigates…”
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Reduction of Dose Delivered to Organs at Risk in Prostate Cancer Patients via Image-Guided Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-03-2010)“…Purpose To determine whether image guidance can improve the dose delivered to target organs and organs at risk (OARs) for prostate cancer patients treated with…”
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18
Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction
Published in Circulation (New York, N.Y.) (28-06-2005)“…Angiotensin-converting enzyme (ACE) inhibitors have been shown to attenuate left ventricular (LV) enlargement in association with reducing mortality after…”
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19
Prevention of heart failure in patients in the heart outcomes prevention evaluation (HOPE) study
Published in Circulation (New York, N.Y.) (11-03-2003)“…Previous trials in the prevention of heart failure have been restricted to patients with low ejection fraction or hypertension. We assessed an…”
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20
Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo Study
Published in European heart journal (01-01-2009)“…Aims To assess the relationship between left atrial (LA) size and outcome after high-risk myocardial infarction (MI) and to study dynamic changes in LA size…”
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