Search Results - "Arnold, Louise"
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Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival
Published in Blood (23-06-2011)“…Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal hematopoietic disorder with increased mortality and morbidity resulting from intravascular…”
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Treatment outcomes of complement protein C5 inhibition in 509 UK patients with paroxysmal nocturnal hemoglobinuria
Published in Blood (21-03-2024)“…•Eculizumab and ravulizumab are effective, well-tolerated therapies for patients with PNH, and the risks of complications are low.•Survival is inferior to age-…”
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COVID‐19 infection in patients on anti‐complement therapy: The Leeds National Paroxysmal Nocturnal Haemoglobinuria service experience
Published in British journal of haematology (01-10-2020)Get full text
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Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria
Published in Haematologica (Roma) (01-03-2019)Get full text
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Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization
Published in Haematologica (Roma) (01-04-2010)“…Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively…”
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Clinical and morphological predictors of outcome in older aplastic anemia patients treated with eltrombopag
Published in Haematologica (Roma) (01-11-2019)Get full text
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The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab
Published in British journal of haematology (01-05-2010)“…Summary In Paroxysmal nocturnal haemoglobinuria (PNH), pregnancy is associated with increased maternal and foetal complications to such an extent that the…”
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Peer nominations as related to academic attainment, empathy, personality, and specialty interest
Published in Academic medicine (01-06-2011)“…To test the hypotheses that peer nomination is associated with measures of (1) academic performance, (2) empathy, (3) personality, and (4) specialty interest…”
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Improving cytopenia with splenic artery embolization in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab
Published in International journal of hematology (01-12-2013)“…Paroxysmal nocturnal hemoglobinuria is a rare acquired stem cell disorder characterized by intravascular hemolysis, aplasia and an increased risk of…”
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Assessing professional behavior: yesterday, today, and tomorrow
Published in Academic medicine (01-06-2002)“…The author interprets the state of the art of assessing professional behavior. She defines the concept of professionalism, reviews the psychometric properties…”
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Monitoring Patient Reported Outcomes in PNH: Interim Results of a Market Research with florio ® PNH
Published in Blood (02-11-2023)“…Background: Patients withparoxysmal nocturnal hemoglobinuria (PNH), an ultra-rare, acquired disorder, report various cardiovascular, gastrointestinal,…”
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Chinese Adolescents' Reasoning About Democratic and Authority-Based Decision Making in Peer, Family, and School Contexts
Published in Child development (01-05-2003)“…This study explored the judgments and reasoning of Chinese adolescents (13-18 years of age) from 3 regions of mainland China (N = 574) regarding procedures for…”
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Optimizing surgical teaching through the lens of sociocultural learning theory
Published in The American journal of surgery (01-07-2022)“…The objective of this study was to identify intraoperative instructional strategies that embody the ways that learning occurs in the social contexts of…”
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Experience of compassionate-use pegcetacoplan for paroxysmal nocturnal hemoglobinuria
Published in Blood (05-01-2023)Get full text
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A Free-Market Approach to the Match: A Proposal Whose Time Has Not Yet Come
Published in Academic medicine (01-01-2018)“…The authors respond to a proposal in this issue of Academic Medicine by Ray, Bishop, and Dow, who recommend adopting a free-market approach to the Match in…”
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Paroxysmal Nocturnal Haemoglobinuria (PNH) Arising from Non-Canonical Mutations
Published in Blood (02-11-2023)“…Introduction Acquired somatic mutations in the X-linked PIGA gene are the most commonly described pathological mutations found in the serious haematopoietic…”
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Micro‐relational interdependencies are the essence of teaching and learning in the OR
Published in Medical education (01-12-2020)“…Context In the high‐stakes, time‐critical environment of the operating room (OR), attendings and residents strive to complete safe, effective surgeries and…”
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Thrombotic Events with Neisseria Meningitidis Vaccination in Patients with Paroxysmal Nocturnal Hemoglobinuria, UK Experience
Published in Blood (05-11-2020)“…Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hemolytic and thrombotic condition. Patients can experience severe anemia due to intravascular hemolysis,…”
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Incomplete Complement Inhibition in Patients with PNH on Eculizumab - 5 Year Experience from the National PNH Service Leeds
Published in Blood (05-11-2020)“…Background Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare acquired disorder characterised by intravascular hemolysis and thrombosis. Patients with…”
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