Search Results - "Arnold, DL"

Use of proton magnetic resonance spectroscopy for monitoring disease progression in multiple sclerosis by Arnold, D L, Riess, G T, Matthews, P M, Francis, G S, Collins, D L, Wolfson, C, Antel, J P

“…Decreases in brain N-acetylaspartate are associated with neuronal loss or dysfunction. We report a longitudinal study in which changes in the N-acetylaspartate…”
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Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis by Hauser, Stephen L, Bar-Or, Amit, Comi, Giancarlo, Giovannoni, Gavin, Hartung, Hans-Peter, Hemmer, Bernhard, Lublin, Fred, Montalban, Xavier, Rammohan, Kottil W, Selmaj, Krzysztof, Traboulsee, Anthony, Wolinsky, Jerry S, Arnold, Douglas L, Klingelschmitt, Gaelle, Masterman, Donna, Fontoura, Paulo, Belachew, Shibeshih, Chin, Peter, Mairon, Nicole, Garren, Hideki, Kappos, Ludwig

“…In two trials involving patients with relapsing multiple sclerosis, the anti-CD20+ monoclonal antibody ocrelizumab was associated with lower annualized relapse…”
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Pegylated interferon beta-1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, double-blind study by Calabresi, Peter A, Prof, Kieseier, Bernd C, MD, Arnold, Douglas L, Prof, Balcer, Laura J, Prof, Boyko, Alexey, Prof, Pelletier, Jean, MD, Liu, Shifang, PhD, Zhu, Ying, PhD, Seddighzadeh, Ali, MD, Hung, Serena, MD, Deykin, Aaron, MD

“…Summary Background Subcutaneous pegylated interferon (peginterferon) beta-1a is being developed for treatment of relapsing multiple sclerosis, with less…”
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115  Impact of siponimod on myelination across SPMS subgroups: post-hoc analysis from EXPAND MRI substudy by Arnold, DL, Bar-Or, A, Cree, BAC, Giovannoni, G, Gold, R, Vermersch, P, Piani-Meier, D, Arnould, S, Kappos, L

“…BackgroundChanges in magnetization transfer ratio (MTR) are a marker of changes in myelin density and brain tissue integrity. Siponimod improved lesional MTR…”
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Investigation of human mitochondrial myopathies by phosphorus magnetic resonance spectroscopy by Arnold, D L, Taylor, D J, Radda, G K

“…Abnormal mitochondria are an increasingly recognized cause of neuromuscular disease. We have used phosphorus magnetic resonance spectroscopy to monitor…”
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Regional brain atrophy in children with multiple sclerosis by Aubert-Broche, B., Fonov, V., Ghassemi, R., Narayanan, S., Arnold, D.L., Banwell, B., Sled, J.G., Collins, D.L.

“…We used cross-sectional tensor-based morphometry to visualize reduced volume in the whole brains of pediatric patients with multiple sclerosis, relative to…”
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Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of the hippocampus, amygdala and parahippocampal region by Bernasconi, N., Bernasconi, A., Caramanos, Z., Antel, S. B., Andermann, F., Arnold, D. L.

“…Despite neuropathological and electrophysiological evidence for the involvement of parahippocampal structures in temporal lobe epilepsy (TLE), little attention…”
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OCRELIZUMAB IN PRIMARY PROGRESSIVE MS: THE ORATORIO STUDY by Giovannoni, G, Arnold, DL, Bar-Or, A, de Seze, J, Hemmer, B, Montalban, X, Rammohan, K, Wolinsky, J

“…IntroductionB cells are implicated in MS pathophysiology, including primary progressive MS (PPMS). Ocrelizumab (OCR) is a humanised monoclonal antibody that…”
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OCRELIZUMAB VS INTERFERON β-1A IN RELAPSING MS: TWO STUDIES by Silber, E, Arnold, DL, Bar-Or, A, Comi, G, Hartung, HP, Hauser, SL, Lublin, F, Selmaj, K, Traboulsee, A, Kappos, L

“…IntroductionB cells are implicated in MS pathophysiology. Ocrelizumab (OCR) is a humanised monoclonal antibody that selectively targets CD20+ B cells. OCR was…”
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OCRELIZUMAB VS INTERFERON [beta]-1A IN RELAPSING MS: TWO STUDIES by Silber, E, Arnold, DL, Bar-Or, A, Comi, G, Hartung, HP, Hauser, SL, Lublin, F, Selmaj, K, Traboulsee, A, Kappos, L

“…Introduction B cells are implicated in MS pathophysiology. Ocrelizumab (OCR) is a humanised monoclonal antibody that selectively targets CD20+ B cells. OCR was…”
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Standardized MR imaging protocol for multiple sclerosis : Consortium of MS centers consensus guidelines by SIMON, J. H, LI, D, WOLINSKY, J. S, TRABOULSEE, A, COYLE, P. K, ARNOLD, D. L, BARKHOF, F, FRANK, J. A, GROSSMAN, R, PATY, D. W, RADUE, E. W

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Diffusion tensor magnetic resonance imaging in very early onset pediatric multiple sclerosis by Rocca, MA, Sonkin, M, Copetti, M, Pagani, E, Arnold, DL, Narayanan, S, Sled, JG, Banwell, B, Filippi, M

“…Objectives: Active myelination during childhood may influence the impact of multiple sclerosis (MS) on brain structural integrity. We studied normal-appearing…”
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Phylogeny of the genus Pseudomonas: intrageneric structure reconstructed from the nucleotide sequences of gyrB and rpoD genes by Yamamoto, Satoshi, Kasai, Hiroaki, Arnold, Dawn L, Jackson, Robert W, Vivian, Alan, Harayama, Shigeaki

“…Marine Biotechnology Institute, Kamaishi Laboratories, Kamaishi City, Iwate 026, Japan 1 Centre for Research in Plant Science, Faculty of Applied Sciences,…”
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Preventing brain atrophy should be the gold standard of effective therapy in multiple sclerosis (after the first year of treatment): Commentary by Arnold, DL, De Stefano, N

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Relating neocortical pathology to disability progression in multiple sclerosis using MRI by Chen, J.T., Narayanan, S., Collins, D.L., Smith, S.M., Matthews, P.M., Arnold, D.L.

“…Cortical grey matter (cGM) develops a substantial burden of pathology in multiple sclerosis (MS). Previous cross-sectional studies have suggested a…”
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Factors associated with emotional and behavioral outcomes in adolescents with multiple sclerosis by Till, C, Udler, E, Ghassemi, R, Narayanan, S, Arnold, DL, Banwell, BL

“…Background: Multiple sclerosis (MS) onset during adolescence has the potential to disrupt a key period of psychosocial maturation. Objective: We aimed to…”
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Exposure to Host Resistance Mechanisms Drives Evolution of Bacterial Virulence in Plants by Pitman, Andrew R., Jackson, Robert W., Mansfield, John W., Kaitell, Victor, Thwaites, Richard, Arnold, Dawn L.

“…Bacterial pathogenicity to plants and animals has evolved through an arms race of attack and defense. Key players are bacterial effector proteins, which are…”
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Reliability, validity, and applicability of the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0) for adults with multiple sclerosis by Demers, L., Monette, M., Lapierre, Y., Arnold, D. L., Wolfson, C.

“…Purpose : To investigate the measurement properties of the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST 2.0) with respect to…”
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Voxel-based analysis of the evolution of magnetization transfer ratio to quantify remyelination and demyelination with histopathological validation in a multiple sclerosis lesion by Chen, J.T., Kuhlmann, T., Jansen, G.H., Collins, D.L, Atkins, H.L., Freedman, M.S., O’Connor, P.W., Arnold, D.L.

“…We present a new method for advanced image processing to separately quantify significant decreases and increases in the magnetization transfer ratio (MTR) of…”
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Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis by Vollmer, T, Panitch, H, Bar-Or, A, Dunn, J, Freedman, MS, Gazda, SK, Campagnolo, D, Deutsch, F, Arnold, DL

“…Forty relapsing multiple sclerosis patients with 1–15 gadolinium (Gd)-enhancing lesions on screening brain magnetic resonance imaging (MRI) and Expanded…”
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