Search Results - "Arnold, Angela"

High-Grade Serous Ovarian Cancer: Associations between BRCA Mutation Status, CT Imaging Phenotypes, and Clinical Outcomes by Nougaret, Stephanie, Lakhman, Yulia, Gönen, Mithat, Goldman, Debra A, Miccò, Maura, D'Anastasi, Melvin, Johnson, Sarah A, Juluru, Krishna, Arnold, Angela G, Sosa, Ramon E, Soslow, Robert A, Vargas, Hebert Alberto, Hricak, Hedvig, Kauff, Noah D, Sala, Evis

“…Purpose To investigate the associations between BRCA mutation status and computed tomography (CT) phenotypes of high-grade serous ovarian cancer (HGSOC) and to…”
Get full text

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas by Jonsson, Philip, Lin, Andrew L, Young, Robert J, DiStefano, Natalie M, Hyman, David M, Li, Bob T, Berger, Michael F, Zehir, Ahmet, Ladanyi, Marc, Solit, David B, Arnold, Angela G, Stadler, Zsofia K, Mandelker, Diana, Goldberg, Michael E, Chmielecki, Juliann, Pourmaleki, Maryam, Ogilvie, Shahiba Q, Chavan, Shweta S, McKeown, Andrew T, Manne, Malbora, Hyde, Allison, Beal, Kathryn, Yang, T Jonathan, Nolan, Craig P, Pentsova, Elena, Omuro, Antonio, Gavrilovic, Igor T, Kaley, Thomas J, Diamond, Eli L, Stone, Jacqueline B, Grommes, Christian, Boire, Adrienne, Daras, Mariza, Piotrowski, Anna F, Miller, Alexandra M, Gutin, Philip H, Chan, Timothy A, Tabar, Viviane S, Brennan, Cameron W, Rosenblum, Marc, DeAngelis, Lisa M, Mellinghoff, Ingo K, Taylor, Barry S

“…The genomic landscape of gliomas has been characterized and now contributes to disease classification, yet the relationship between molecular profile and…”
Get full text

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms by Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O'Reilly, Eileen M

“…Identification of pathogenic germline alterations (PGAs) has important clinical and therapeutic implications in pancreas cancer. We performed comprehensive…”
Get full text

The RAD51D c.82GA variant disrupts normal splicing and is associated with hereditary ovarian cancer by Yang, Ciyu, Arnold, Angela G, Catchings, Amanda, Rai, Vikas, Stadler, Zsofia K, Zhang, Liying

“…Purpose Mutations in RAD51D are associated with a predisposition to primary ovarian, fallopian tube, and peritoneal carcinoma. Our study aims to characterize a…”
Get full text

Cancer Susceptibility Mutations in Patients With Urothelial Malignancies by Carlo, Maria I, Ravichandran, Vignesh, Srinavasan, Preethi, Bandlamudi, Chaitanya, Kemel, Yelena, Ceyhan-Birsoy, Ozge, Mukherjee, Semanti, Mandelker, Diana, Chaim, Joshua, Knezevic, Andrea, Rana, Satshil, Fnu, Zarina, Breen, Kelsey, Arnold, Angela G, Khurram, Aliya, Tkachuk, Kaitlyn, Cipolla, Catharine K, Regazzi, Ashley, Hakimi, A Ari, Al-Ahmadie, Hikmat, Dalbagni, Guido, Cadoo, Karen A, Walsh, Michael F, Teo, Min-Yuen, Funt, Samuel A, Coleman, Jonathan A, Bochner, Bernard H, Iyer, Gopa, Solit, David B, Stadler, Zsofia K, Zhang, Liying, Rosenberg, Jonathan E, Taylor, Barry S, Robson, Mark E, Berger, Michael F, Vijai, Joseph, Bajorin, Dean F, Offit, Kenneth

“…Urothelial cancers (UCs) have a substantial hereditary component, but, other than their association with Lynch syndrome, the contribution of genetic risk…”
Get full text

The RAD51D c.82G>A (p.Val28Met) variant disrupts normal splicing and is associated with hereditary ovarian cancer by Yang, Ciyu, Arnold, Angela G., Catchings, Amanda, Rai, Vikas, Stadler, Zsofia K., Zhang, Liying

“…Purpose Mutations in RAD51D are associated with a predisposition to primary ovarian, fallopian tube, and peritoneal carcinoma. Our study aims to characterize a…”
Get full text

Disparities in cancer genetics care by race/ethnicity among pan‐cancer patients with pathogenic germline variants by Liu, Ying L., Maio, Anna, Kemel, Yelena, Salo‐Mullen, Erin E., Sheehan, Margaret, Tejada, Prince Ray, Trottier, Magan, Arnold, Angela G., Fleischut, Megan Harlan, Latham, Alicia, Carlo, Maria I., Murciano‐Goroff, Yonina R., Walsh, Michael F., Mandelker, Diana, Mehta, Nikita, Bandlamudi, Chaitanya, Arora, Kanika, Zehir, Ahmet, Berger, Michael F., Solit, David B., Aghajanian, Carol, Diaz, Luis A., Robson, Mark E., Brown, Carol L., Offit, Kenneth, Hamilton, Jada G., Stadler, Zsofia K.

“…Background Germline risk assessment is increasing as part of cancer care; however, disparities in subsequent genetic counseling are unknown. Methods Pan‐cancer…”
Get full text

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma by Carlo, Maria I, Mukherjee, Semanti, Mandelker, Diana, Vijai, Joseph, Kemel, Yelena, Zhang, Liying, Knezevic, Andrea, Patil, Sujata, Ceyhan-Birsoy, Ozge, Huang, Kuo-Cheng, Redzematovic, Almedina, Coskey, Devyn T, Stewart, Carolyn, Pradhan, Nisha, Arnold, Angela G, Hakimi, A Ari, Chen, Ying-Bei, Coleman, Jonathan A, Hyman, David M, Ladanyi, Marc, Cadoo, Karen A, Walsh, Michael F, Stadler, Zsofia K, Lee, Chung-Han, Feldman, Darren R, Voss, Martin H, Robson, Mark, Motzer, Robert J, Offit, Kenneth

“…Identification of patients with hereditary renal cell carcinoma (RCC) is important for cancer screening and, in patients with advanced disease, for guiding…”
Get more information

An evaluation of the effects of response interruption redirection and matched stimulation on vocal stereotypy by Gibney, Cara, Phillips, Katrina J., Arnold‐Saritepe, Angela, Taylor, Sarah Ann

“…Stereotypy is one of the core diagnostic features of autism spectrum disorder and warrants behavioral intervention when it negatively impacts the person's…”
Get full text

Comprehensive analysis of germline drivers in endometrial cancer by Gordhandas, Sushmita, Rios-Doria, Eric, Cadoo, Karen A, Catchings, Amanda, Maio, Anna, Kemel, Yelena, Sheehan, Margaret, Ranganathan, Megha, Green, Dina, Aryamvally, Anjali, Arnold, Angela G, Salo-Mullen, Erin, Manning-Geist, Beryl, Sia, Tiffany, Selenica, Pier, Da Cruz Paula, Arnaud, Vanderbilt, Chad, Misyura, Maksym, Leitao, Mario M, Mueller, Jennifer J, Makker, Vicky, Rubinstein, Maria, Friedman, Claire F, Zhou, Qin, Iasonos, Alexia, Latham, Alicia, Carlo, Maria I, Murciano-Goroff, Yonina R, Will, Marie, Walsh, Michael F, Issa Bhaloo, Shirin, Ellenson, Lora H, Ceyhan-Birsoy, Ozge, Berger, Michael F, Robson, Mark E, Abu-Rustum, Nadeem, Aghajanian, Carol, Offit, Kenneth, Stadler, Zsofia, Weigelt, Britta, Mandelker, Diana L, Liu, Ying L

“…Abstract Background We sought to determine the prevalence of germline pathogenic variants (gPVs) in unselected patients with endometrial cancer (EC), define…”
Get full text

Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations by Shu, Catherine A, Pike, Malcolm C, Jotwani, Anjali R, Friebel, Tara M, Soslow, Robert A, Levine, Douglas A, Nathanson, Katherine L, Konner, Jason A, Arnold, Angela G, Bogomolniy, Faina, Dao, Fanny, Olvera, Narciso, Bancroft, Elizabeth K, Goldfrank, Deborah J, Stadler, Zsofia K, Robson, Mark E, Brown, Carol L, Leitao, Jr, Mario M, Abu-Rustum, Nadeem R, Aghajanian, Carol A, Blum, Joanne L, Neuhausen, Susan L, Garber, Judy E, Daly, Mary B, Isaacs, Claudine, Eeles, Rosalind A, Ganz, Patricia A, Barakat, Richard R, Offit, Kenneth, Domchek, Susan M, Rebbeck, Timothy R, Kauff, Noah D

“…The link between BRCA mutations and uterine cancer is unclear. Therefore, although risk-reducing salpingo-oophorectomy (RRSO) is standard treatment among women…”
Get more information

Outcomes of incidentally detected ovarian cancers diagnosed at time of risk-reducing salpingo-oophorectomy in BRCA mutation carriers by Cowan, Renee, Nobre, Silvana Pedra, Pradhan, Nisha, Yasukawa, Maya, Zhou, Qin C., Iasonos, Alexia, Soslow, Robert A., Arnold, Angela G., Trottier, Magan, Catchings, Amanda, Roche, Kara Long, Gardner, Ginger, Robson, Mark, Abu Rustum, Nadeem R., Aghajanian, Carol, Cadoo, Karen

“…Prior data suggested that women with incidentally detected occult invasive ovarian cancer (OIOC) at the time of risk-reducing salpingo-oophorectomy (RRSO) for…”
Get full text

Improved survival for BRCA2‐associated serous ovarian cancer compared with both BRCA‐negative and BRCA1‐associated serous ovarian cancer by Hyman, David M., Zhou, Qin, Iasonos, Alexia, Grisham, Rachel N., Arnold, Angela G., Phillips, Mary F., Bhatia, Jasmine, Levine, Douglas A., Aghajanian, Carol, Offit, Kenneth, Barakat, Richard R., Spriggs, David R., Kauff, Noah D.

“…BACKGROUND: Multiple observational studies have suggested that breast cancer gene (BRCA)‐associated ovarian cancers have improved survival compared with…”
Get full text

Invasion patterns of metastatic high-grade serous carcinoma of ovary or fallopian tube associated with BRCA deficiency by Reyes, M Carolina, Arnold, Angela G, Kauff, Noah D, Levine, Douglas A, Soslow, Robert A

“…High-grade serous carcinomas of the uterine adnexa with BRCA1 deficiency (high-grade serous carcinomas-BRCA) have recently been described to demonstrate…”
Get full text

Resolving pathogenicity classification for the CDH1 c.[715G>A] (p.Gly239Arg) Variant by Yelskaya, Zarina, Arnold, Angela G, Marcell, Vanessa J, Tang, Laura H, Salo-Mullen, Erin E, Strong, Vivian E, Stadler, Zsofia K, Zhang, Liying

“…Hereditary Diffuse Gastric Cancer (HDGC) syndrome is associated with CDH1 germline likely pathogenic/pathogenic variants. Carriers of CDH1 germline likely…”
Get full text

Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients by Ceyhan-Birsoy, Ozge, Jayakumaran, Gowtham, Kemel, Yelena, Misyura, Maksym, Aypar, Umut, Jairam, Sowmya, Yang, Ciyu, Li, Yirong, Mehta, Nikita, Maio, Anna, Arnold, Angela, Salo-Mullen, Erin, Sheehan, Margaret, Syed, Aijazuddin, Walsh, Michael, Carlo, Maria, Robson, Mark, Offit, Kenneth, Ladanyi, Marc, Reis-Filho, Jorge S, Stadler, Zsofia K, Zhang, Liying, Latham, Alicia, Zehir, Ahmet, Mandelker, Diana

“…Genetic testing (GT) for hereditary cancer predisposition is traditionally performed on selected genes based on established guidelines for each cancer type…”
Get full text

Correction to: Resolving pathogenicity classification for the CDH1 c.[715G>A] (p.Gly239Arg) variant by Yelskaya, Zarina, Arnold, Angela G, Marcell, Vanessa J, Tang, Laura H, Salo-Mullen, Erin E, Strong, Vivian E, Stadler, Zsofia K, Zhang, Liying

“…A Correction to this paper has been published: https://doi.org/10.1038/s41431-021-00895-w…”
Get full text

Invasion Patterns of Metastatic Extrauterine High-grade Serous Carcinoma With BRCA Germline Mutation and Correlation With Clinical Outcomes by Hussein, Yaser R, Ducie, Jennifer A, Arnold, Angela G, Kauff, Noah D, Vargas-Alvarez, Hebert A, Sala, Evis, Levine, Douglas A, Soslow, Robert A

“…Characteristic histopathologic features have been described in high-grade serous carcinoma associated with BRCA abnormalities (HGSC-BRCA), which are known to…”
Get full text

Psychosocial factors associated with the uptake of contralateral prophylactic mastectomy among BRCA1/2 mutation noncarriers with newly diagnosed breast cancer by Hamilton, Jada G., Genoff, Margaux C., Salerno, Melissa, Amoroso, Kimberly, Boyar, Sherry R., Sheehan, Margaret, Fleischut, Megan Harlan, Siegel, Beth, Arnold, Angela G., Salo-Mullen, Erin E., Hay, Jennifer L., Offit, Kenneth, Robson, Mark E.

“…Purpose Women who are newly diagnosed with breast cancer may consider contralateral prophylactic mastectomy (CPM) to reduce their future risk of cancer in…”
Get full text

Characterization of a novel germline PALB2 duplication in a hereditary breast and ovarian cancer family by Yang, Ciyu, Arnold, Angela G., Trottier, Magan, Sonoda, Yukio, Abu-Rustum, Nadeem R., Zivanovic, Oliver, Robson, Mark E., Stadler, Zsofia K., Walsh, Michael F., Hyman, David M., Offit, Kenneth, Zhang, Liying

“…Purpose Mutations in PALB2 have been associated with a predisposition to breast and pancreatic cancers. This study aims to characterize a novel PALB2 exon 13…”
Get full text