Search Results - "Arnett, Frank C."

Osteopontin in Systemic Sclerosis and Its Role in Dermal Fibrosis by Wu, Minghua, Schneider, Daniel J., Mayes, Maureen D., Assassi, Shervin, Arnett, Frank C., Tan, Filemon K., Blackburn, Michael R., Agarwal, Sandeep K.

“…Osteopontin (OPN) is a matricellular protein with proinflammatory and profibrotic properties. Previous reports demonstrate a role for OPN in wound healing and…”
Get full text

Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort by Assassi, Shervin, Sharif, Roozbeh, Lasky, Robert E, McNearney, Terry A, Estrada-Y-Martin, Rosa M, Draeger, Hilda, Nair, Deepthi K, Fritzler, Marvin J, Reveille, John D, Arnett, Frank C, Mayes, Maureen D

“…The objective of the present study was to examine the association of baseline demographic and clinical characteristics with sequentially obtained measurements…”
Get full text

Clinical and genetic factors predictive of mortality in early systemic sclerosis by Assassi, Shervin, del Junco, Deborah, Sutter, Kari, McNearney, Terry A., Reveille, John D., Karnavas, Andrew, Gourh, Pravitt, Estrada‐Y‐Martin, Rosa M., Fischbach, Michael, Arnett, Frank C., Mayes, Maureen D.

“…Objective To investigate the clinical and genetic variables at initial presentation that predict survival in the Genetics versus Environment in Scleroderma…”
Get full text

Right bundle branch block: a predictor of mortality in early systemic sclerosis by Draeger, Hilda T, Assassi, Shervin, Sharif, Roozbeh, Gonzalez, Emilio B, Harper, Brock E, Arnett, Frank C, Manzoor, Ameena, Lange, Richard A, Mayes, Maureen D

“…To evaluate the prognostic significance of baseline electrocardiogram (ECG) abnormalities in a multiethnic cohort of patients with early systemic sclerosis…”
Get full text

Primary Biliary Cirrhosis (PBC), PBC Autoantibodies, and Hepatic Parameter Abnormalities in a Large Population of Systemic Sclerosis Patients by ASSASSI, Shervin, FRITZLER, Marvin J, MAYES, Maureen D, ARNETT, Frank C, NORMAN, Gary L, SHAH, Kairav R, GOURH, Pravitt, MANEK, Neil, PERRY, Marilyn, GANESH, Devi, RAHBAR, Mohammad H

“…Objective. To investigate the diagnostic accuracy of antimitochondrial antibodies (AMA), sp100, and gp210 antibodies for primary biliary cirrhosis (PBC) in a…”
Get full text

Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic aneurysms by He, Rumin, MD, Guo, Dong-Chuan, PhD, Sun, Wei, PhD, Papke, Christina L., BS, Duraisamy, Senthil, PhD, Estrera, Anthony L., MD, Safi, Hazim J., MD, Ahn, Chul, PhD, Maximilian Buja, L., MD, Arnett, Frank C., MD, Zhang, Jingwu, MD, Geng, Yong-Jian, MD, PhD, Milewicz, Dianna M., MD, PhD

“…Objective This study sought to characterize the inflammatory infiltrate in ascending thoracic aortic aneurysm in patients with Marfan syndrome, familial…”
Get full text

HLA–DRB10407 and 1304 are risk factors for scleroderma renal crisis by Nguyen, Binh, Mayes, Maureen D., Arnett, Frank C., del Junco, Deborah, Reveille, John D., Gonzalez, Emilio B., Draeger, Hilda T., Perry, Marilyn, Hendiani, Amir, Anand, Kiran K., Assassi, Shervin

“…Objective To examine the predictive role of HLA genetic markers in scleroderma renal crisis (SRC), beyond the known clinical correlates, in a large population…”
Get full text

DRB115 Allele Is a Risk Factor for PR3-ANCA Disease in African Americans by YALI CAO, SCHMITZ, John L, FALK, Ronald J, PRESTON, Gloria A, JIAJIN YANG, HOGAN, Susan L, BUNCH, Donna, YICHUN HU, JENNETTE, Caroline E, BERG, Elisabeth A, ARNETT, Frank C, JENNETTE, J. Charles

“…Anti-neutrophil cytoplasmic autoantibody (ANCA) disease rarely occurs in African Americans and risk factors for the disease in this population are unknown…”
Get full text

Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis by Carmona, F David, Gutala, Ramana, Simeón, Carmen P, Carreira, Patricia, Ortego-Centeno, Norberto, Vicente-Rabaneda, Esther, García-Hernández, Francisco J, García de la Peña, Paloma, Fernández-Castro, Mónica, Martínez-Estupiñán, Lina, Egurbide, María Victoria, Tsao, Betty P, Gourh, Pravitt, Agarwal, Sandeep K, Assassi, Shervin, Mayes, Maureen D, Arnett, Frank C, Tan, Filemon K, Martín, Javier

“…Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) are related chronic autoimmune diseases of complex aetiology in which the interferon (IFN)…”
Get more information

Association of Interleukin 23 Receptor Polymorphisms with Anti-Topoisomerase-I Positivity and Pulmonary Hypertension in Systemic Sclerosis by AGARWAL, Sandeep K, GOURH, Pravitt, SHETE, Sanjay, PAZ, Gene, DIVECHA, Dipal, REVEILLE, John D, ASSASSI, Shervin, TAN, Filemon K, MAYES, Maureen D, ARNETT, Frank C

“…Objective. IL23R has been identified as a susceptibility gene for development of multiple autoimmune diseases. We investigated the possible association of…”
Get full text

Genetics and Genomic Studies in Scleroderma (Systemic Sclerosis) by Agarwal, Sandeep K., MD, PhD, Tan, Filemon K., MD, PhD, Arnett, Frank C., MD

“…It currently is believed that scleroderma is a complex polygenic disease that occurs in genetically predisposed individuals who have encountered specific…”
Get full text

Determinants of Work Disability in Patients with Systemic Sclerosis: A Longitudinal Study of the GENISOS Cohort by Sharif, Roozbeh, MD, Mayes, Maureen D., MD, MPH, Nicassio, Perry M., PhD, Gonzalez, Emilio B., MD, Draeger, Hilda, MD, McNearney, Terry A., MD, Estrada-Y-Martin, Rosa M., MD, MSc, FCCP, Nair, Deepthi K., MS, Reveille, John D., MD, Arnett, Frank C., MD, Assassi, Shervin, MD, MS

“…Objectives To determine the prevalence, correlates, and predictors of work disability (WD) in the G enetics versus EN vironment I n S cleroderma O utcome S…”
Get full text

Association Study of ITGAM, ITGAX, and CD58 Autoimmune Risk Loci in Systemic Sclerosis: Results from 2 Large European Caucasian Cohorts by COUSTET, Baptiste, AGARWAL, Sandeep K, LUC CRACOWSKI, Jean, TIEV, Kiet, SIBILIA, Jean, MOUTHON, Luc, FRANCES, Camille, AMOURA, Zahir, CARPENTIER, Patrick, MEYER, Olivier, KAHAN, Andre, BOILEAU, Catherine, GOURH, Pravitt, ARNETT, Frank C, ALLANORE, Yannick, GUEDJ, Mickael, MAYES, Maureen D, DIEUDE, Philippe, WIPFF, Julien, AVOUAC, Jerome, HACHULLA, Eric, DIOT, Elisabeth

“…Accumulating evidence shows that shared autoimmunity is critical for the pathogenesis of many autoimmune diseases. Systemic sclerosis (SSc) belongs to the…”
Get full text

Systemic sclerosis in 3 US ethnic groups: A comparison of clinical, sociodemographic, serologic, and immunogenetic determinants by Reveille, John D., Fischbach, Michael, McNearney, Terry, Friedman, Alan W., Aguilar, Martha B., Lisse, Jeffrey, Fritzler, Marvin J., Ahn, Chul, Arnett, Frank C.

“…Objective: To determine whether ethnic factors influence the presentation, serologic expression and immunogenetics of systemic sclerosis (SSc), patients from 3…”
Get full text

Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus by Wu, Hui, Boackle, Susan A, Hanvivadhanakul, Punchong, Ulgiati, Daniela, Grossman, Jennifer M, Lee, Youngho, Shen, Nan, Abraham, Lawrence J, Mercer, Timothy R, Park, Elly, Hebert, Lee A, Rovin, Brad H, Birmingham, Dan J, Chang, Deh-Ming, Chen, Chung Jen, McCurdy, Deborah, Badsha, Humeira M, Thong, Bernard Y.H, Chng, Hiok H, Arnett, Frank C, Wallace, Daniel J, Yu, C. Yung, Hahn, Bevra H, Cantor, Rita M, Tsao, Betty P

“…A genomic region on distal mouse chromosome 1 and its syntenic human counterpart 1q23-42 show strong evidence of harboring lupus susceptibility genes. We found…”
Get full text

Major Histocompatibility Complex Class I and Class II Alleles May Confer Susceptibility to or Protection Against Morphea: Findings From the Morphea in Adults and Children Cohort by Jacobe, Heidi, Ahn, Chul, Arnett, Frank C., Reveille, John D.

“…Objective To determine the HLA class I and class II alleles of the human major histocompatibility complex showing an association with morphea (localized…”
Get full text

Differential dynamic properties of scleroderma fibroblasts in response to perturbation of environmental stimuli by Xiong, Momiao, Arnett, Frank C, Guo, Xinjian, Xiong, Hao, Zhou, Xiaodong

“…Diseases are believed to arise from dysregulation of biological systems (pathways) perturbed by environmental triggers. Biological systems as a whole are not…”
Get full text

Is scleroderma an autoantibody mediated disease? by Arnett, Frank C

“…PURPOSE OF REVIEWResearch into the pathogenesis of systemic sclerosis and other fibrotic conditions is becoming increasingly broad and sophisticated. In the…”
Get full text

Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls by Arnett, Frank C, Gourh, Pravitt, Shete, Sanjay, Ahn, Chul W, Honey, Robert E, Agarwal, Sandeep K, Tan, Filemon K, McNearney, Terry, Fischbach, Michael, Fritzler, Marvin J, Mayes, Maureen D, Reveille, John D

“…To determine human leucocyte antigen-class II (HLA-class II) (DRB1, DQB1, DQA1 and DPB1) alleles, haplotypes and shared epitopes associated with scleroderma…”
Get more information

Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis by Gourh, Pravitt, Arnett, Frank C, Tan, Filemon K, Assassi, Shervin, Divecha, Dipal, Paz, Gene, McNearney, Terry, Draeger, Hilda, Reveille, John D, Mayes, Maureen D, Agarwal, Sandeep K

“…It is increasingly being appreciated that multiple autoimmune diseases share common susceptibility genes. The tumour necrosis factor ligand superfamily member…”
Get more information