Search Results - "Arnett, Azlann"
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Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome
Published in eLife (11-08-2021)“…Maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. Canonical interferon (IFN) signaling controls…”
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Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity
Published in Science translational medicine (12-01-2022)“…Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune system, including a shift from naïve to memory T cells…”
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Journal Article -
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Incidence and survival of pediatric and adult hepatocellular carcinoma, United States, 2001–2020
Published in Cancer epidemiology (01-10-2024)“…Hepatocellular carcinoma accounts for approximately 80 % of liver neoplasms. Globally, hepatocellular carcinoma ranks as the third most lethal cancer, with the…”
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The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway
Published in Molecular and cellular biology (24-08-2021)“…Immune health requires innate and adaptive immune cells to engage precisely balanced pro- and anti-inflammatory forces. We employ the concept of chemical…”
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Journal Article