Search Results - "Arndt, Marco"
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Epithelial to Mesenchymal Transition: Expression of the Regulators Snail, Slug, and Twist in Pancreatic Cancer
Published in Clinical cancer research (15-08-2007)“…Purpose: Epithelial to mesenchymal transitions are vital for tumor growth and metastasis. Several inducers of epithelial to mesenchymal transition are…”
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Journal Article -
2
Muscarinic Acetylcholine Receptor M3 Expression and Survival in Human Colorectal Carcinoma-An Unexpected Correlation to Guide Future Treatment?
Published in International journal of molecular sciences (03-05-2023)“…Muscarinic acetylcholine receptor M3 (M3R) has repeatedly been shown to be prominently expressed in human colorectal cancer (CRC), playing roles in…”
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3
Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation
Published in Journal of the American College of Cardiology (01-05-2000)“…OBJECTIVES The purpose of this study was to determine whether atrial expression of the extracellular signal-regulated kinases Erk1/Erk2 and of the…”
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4
Increased expression of ADAM family members in human breast cancer and breast cancer cell lines
Published in Journal of cancer research and clinical oncology (01-01-2005)“…ADAMs (A Disintegrin and Metalloprotease) are multifunctional, membrane-bound cell surface glycoproteins, which have numerous functions in cell growth,…”
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5
Regulation of angiotensin II receptor subtypes during atrial fibrillation in humans
Published in Circulation (New York, N.Y.) (13-06-2000)“…Previous studies have suggested that atrial fibrillation (AF) is associated with the activation of the atrial angiotensin system. However, it is not known…”
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Altered expression of ADAMs (A Disintegrin And Metalloproteinase) in fibrillating human atria
Published in Circulation (New York, N.Y.) (12-02-2002)“…ADAMs (A Disintegrin And Metalloproteinase) are ectoproteases that have recently been reported to be expressed in cardiac tissue. Although they are known to…”
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Investigating Practical Orthogonality Deviations in RSM for Optimized Predictive Reliability Modeling
Published in 2024 Annual Reliability and Maintainability Symposium (RAMS) (22-01-2024)“…Response Surface Methodology (RSM) models may encounter limitations when incorporated with non-orthogonalities in the design matrix. This holds especially when…”
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Conference Proceeding -
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Reliability-Based Decision Methodology for Stress-Strength Optimization of Machine Components
Published in 2022 Annual Reliability and Maintainability Symposium (RAMS) (24-01-2022)“…In this paper, a decision methodology for reliability-based stress-strength design optimization of machine components under economic aspects is described. For…”
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Conference Proceeding -
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Effect of bowel preparation on intestinal permeability and inflammatory response during postoperative ileus in mice
Published in Surgery (01-11-2021)“…Postoperative ileus entails pathophysiological changes in mucosal permeability and an intestinal inflammatory immune response. We hypothesized that…”
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Journal Article -
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Increased proinflammatory cytokines in mesenteric fat in major surgery and Crohn's disease
Published in Surgery (01-06-2021)“…Proinflammatory cytokines play an important role in abdominal surgery and are often associated with the development of postoperative ileus, especially in…”
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Journal Article -
11
Parameter assessment for reliability modeling of machine components using heuristic screening
Published in Forschung im Ingenieurwesen (01-12-2023)“…For the investigation of influence of various parameters on properties and outputs of components or systems, Design of Experiments (DOE) offers the most…”
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12
Gp130 is expressed in pancreatic cancer and can be targeted by the small inhibitor molecule SC144
Published in Journal of cancer research and clinical oncology (01-01-2023)“…Purpose Interleukin 6 (IL-6), Oncostatin M (OSM), and downstream effector STAT3 are pro-tumorigenic agents in pancreatic ductal adenocarcinoma (PDAC)…”
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13
Targeting Interleukin-6/Glycoprotein-130 Signaling by Raloxifene or SC144 Enhances Paclitaxel Efficacy in Pancreatic Cancer
Published in Cancers (11-01-2023)“…Interleukine-6 plays a key role in the progression and poor survival in pancreatic ductal adenocarcinoma (PDAC). The present study aimed to clarify if…”
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14
Blockage of Cholinergic Signaling via Muscarinic Acetylcholine Receptor 3 Inhibits Tumor Growth in Human Colorectal Adenocarcinoma
Published in Cancers (28-06-2021)“…Cholinergic signaling via the muscarinic M3 acetylcholine receptor (M3R) is involved in the development and progression of colorectal cancer (CRC). The present…”
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Journal Article -
15
Immune Phenotypic Characterization of a TRAIL-Knockout Mouse
Published in Cancers (25-02-2023)“…The TNF-superfamily member TRAIL is known to mediate selective apoptosis in tumor cells suggesting this protein as a potential antitumor drug target. However,…”
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16
Increased proinflammatory cytokines in mesenteric fat in major surgery and Crohn disease
Published in Surgery (08-01-2021)“…Proinflammatory cytokines play an important role in abdominal surgery and are often associated with the development of postoperative ileus, especially in Crohn…”
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Journal Article -
17
Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines
Published in International journal of colorectal disease (01-11-2014)“…Purpose The taurine derivative taurolidine (TRD) exerts anti-neoplastic effects in a variety of tumor models. On the other hand, TRD at low doses was shown to…”
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Journal Article -
18
Calpains and cytokines in fibrillating human atria
Published in American journal of physiology. Heart and circulatory physiology (01-07-2002)“…Atrial fibrillation (AF) is accompanied by intracellular calcium overload. The purpose of this study was to assess the role of calcium-dependent calpains and…”
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Journal Article -
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Fluid resuscitation with human albumin or hydroxyethyl starch-are there differences in the healing of experimental intestinal anastomoses?
Published in Scandinavian journal of gastroenterology (01-01-2010)“…Abstract Objectives. Restoration of the macro- and microcirculation is important for the healing of gastrointestinal anastomoses. Colloids and crystalloids are…”
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Journal Article -
20
Role of alanyl aminopeptidase in growth and function of human T cells (review)
Published in International journal of molecular medicine (01-07-1999)“…Alanyl aminopeptidase (APN, CD13) is highly expressed in human monocytes, and anti-CD13 monoclonal antibodies are well established routine markers in leukaemia…”
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