Search Results - "Arnaudo, Nadia"

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis by Mevissen, Tycho E.T., Hospenthal, Manuela K., Geurink, Paul P., Elliott, Paul R., Akutsu, Masato, Arnaudo, Nadia, Ekkebus, Reggy, Kulathu, Yogesh, Wauer, Tobias, El Oualid, Farid, Freund, Stefan M.V., Ovaa, Huib, Komander, David

“…Sixteen ovarian tumor (OTU) family deubiquitinases (DUBs) exist in humans, and most members regulate cell-signaling cascades. Several OTU DUBs were reported to…”
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Regulation of A20 and other OTU deubiquitinases by reversible oxidation by Kulathu, Yogesh, Garcia, Francisco J., Mevissen, Tycho E. T., Busch, Martin, Arnaudo, Nadia, Carroll, Kate S., Barford, David, Komander, David

“…Protein ubiquitination is a highly versatile post-translational modification that regulates as diverse processes as protein degradation and kinase activation…”
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The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle by Arnaudo, Nadia, Fernández, Israel S, McLaughlin, Stephen H, Peak-Chew, Sew Y, Rhodes, Daniela, Martino, Fabrizio

“…N-terminal acetylation of Sir3 is essential for heterochromatin establishment and maintenance in yeast, but its mechanism of action is unknown. The crystal…”
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Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting by Itoh, Toshimasa, Fairall, Louise, Muskett, Frederick W, Milano, Charles P, Watson, Peter J, Arnaudo, Nadia, Saleh, Almutasem, Millard, Christopher J, El-Mezgueldi, Mohammed, Martino, Fabrizio, Schwabe, John W R

“…Recent proteomic studies have identified a novel histone deacetylase complex that is upregulated during mitosis and is associated with cyclin A. This complex…”
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RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX by Pinato, Sabrina, Scandiuzzi, Cristina, Arnaudo, Nadia, Citterio, Elisabetta, Gaudino, Giovanni, Penengo, Lorenza

“…Modulation of chromatin structure has emerged as a critical molecular device to control gene expression. Histones undergo different post-translational…”
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