Search Results - "Armistead, David M."

Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck:  Synthesis, SAR, and in Vivo Antiinflammatory Activity by Martin, Matthew W, Newcomb, John, Nunes, Joseph J, McGowan, David C, Armistead, David M, Boucher, Christina, Buchanan, John L, Buckner, William, Chai, Lilly, Elbaum, Daniel, Epstein, Linda F, Faust, Theodore, Flynn, Shaun, Gallant, Paul, Gore, Anu, Gu, Yan, Hsieh, Faye, Huang, Xin, Lee, Josie H, Metz, Daniela, Middleton, Scot, Mohn, Deanna, Morgenstern, Kurt, Morrison, Michael J, Novak, Perry M, Oliveira-dos-Santos, Antonio, Powers, David, Rose, Paul, Schneider, Stephen, Sell, Stephanie, Tudor, Yanyan, Turci, Susan M, Welcher, Andrew A, White, Ryan D, Zack, Debra, Zhao, Huilin, Zhu, Li, Zhu, Xiaotian, Ghiron, Chiara, Amouzegh, Patricia, Ermann, Monika, Jenkins, James, Johnston, David, Napier, Spencer, Power, Eoin

“…The lymphocyte-specific kinase (Lck) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and NK cells. Genetic evidence in both mice and…”
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Non‐FK506‐binding protein‐12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration by Gold, Bruce G., Armistead, David M., Wang, Min‐Sheng

“…Neurotrophic activity of neuroimmunophilin ligands (FK506 and its nonimmunosuppressant derivatives) has been assumed to be mediated by the FK506‐binding…”
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The total synthesis of the aglycon of avermectin A1a by Danishefsky, Samuel J, Armistead, David M, Wincott, Francine E, Selnick, Harold G, Hungate, Randall

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Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance in vitro by Germann, U A, Shlyakhter, D, Mason, V S, Zelle, R E, Duffy, J P, Galullo, V, Armistead, D M, Saunders, J O, Boger, J, Harding, M W

“…VX-710 or (S)-N[2-Oxo-2-(3,4,5-trimethoxyphenyl)acetyl]-piperidine-2-carboxylic acid 1,7-bis(3-pyridyl)-4-heptyl ester, a novel non-macrocyclic ligand of the…”
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The total synthesis of avermectin A1a by Danishefsky, Samuel J, Armistead, David M, Wincott, Francine E, Selnick, Harold G, Hungate, Randall

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Free-radicals in synthesis. I. A two-step carbolactonization procedure by Burke, Steven D, Fobare, William F, Armistead, David M

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The total synthesis of avermectin A1a. New protocols for the synthesis of novel 2-deoxypyranose systems and their axial glycosides by Danishefsky, Samuel J, Selnick, Harold G, Armistead, David M, Wincott, Francine E

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Polysubstituted dihydropyrans via the enolate Claisen rearrangement. A stereocontrolled route to C-pyranosides by Burke, Steven D, Armistead, David M, Schoenen, Frank J

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Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration by Gold, Bruce G., Armistead, David M., Wang, Min-Sheng

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A Nonimmunosuppressant FKBP-12 Ligand Increases Nerve Regeneration by Gold, Bruce G., Zeleny-Pooley, Michelle, Wang, Min-Sheng, Chaturvedi, Pravin, Armistead, David M.

“…The immunosuppressant drugs FK506 and cyclosporin A inhibit T-cell proliferation via a common mechanism: calcineurin inhibition following binding to their…”
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Total synthesis of ionophore antibiotic X-14547A (indanomycin) by BURKE, S. D, PISCOPIA, A. D, KORT, M. E, MATULENKO, M. A, PARKER, M. H, ARMISTEAD, D. M, SHANKARAN, K

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Synthetic studies on the immunosuppressive agent FK-506: Enantioselective synthesis of a C22C34 fragment by Baker, Robert K., Rupprecht, Kathleen M., Armistead, David M., Boger, Joshua, Frankshun, Robert A., Hodges, Paul J., Hoogsteen, Karst, Pissano, Judith M., Witzel, Bruce E.

“…The C28C32 cyclohexyl group of the natural product, FK-506, was prepared enantioselectively from the iodolactone by replacement of iodide with retention of…”
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Total synthesis of ionophore antibiotic X-14547 A (indanomycin) by Burke, Steven D., Piscopio, Anthony D., Kort, Michael E., Matulenko, Mark A., Parker, Marshall H., Armistead, David M., Shankaran, K.

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