Prevalence of nephropathy among diabetic patients in North American region: A systematic review and meta-analysis

Nephropathy is one of the most common microvascular impediments of diabetes mellitus. In this study, we aimed to estimate the prevalence of nephropathy in diabetic patients across the North American region. Eligible studies were screened out from 3 electronic databases, for example, PubMed, Google S...

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Bibliographic Details
Published in:	Medicine (Baltimore) Vol. 103; no. 38; p. e39759
Main Authors:	Zahra, Sabahat, Saleem, Muhammad Khurram, Ejaz, Khawaja Faizan, Akbar, Amna, Jadoon, Sarosh Khan, Hussain, Shoukat, Ali, Amir Iqbal, Ifty, Mehzabeen, Jannati, Sadia Zafur, Armin, Fariza, Sarker, Deepannita, Islam, Dewan Zubaer, Khandker, Shahad Saif, Khan, Mohammad Saleem, Alvi, Sarosh
Format:	Journal Article
Language:	English
Published:	United States Lippincott Williams & Wilkins 20-09-2024
Subjects:	Canada - epidemiology Diabetic Nephropathies - epidemiology Humans Mexico - epidemiology North America - epidemiology Prevalence Systematic Review and Meta-Analysis United States - epidemiology Canada Mexico United States North America
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Summary:	Nephropathy is one of the most common microvascular impediments of diabetes mellitus. In this study, we aimed to estimate the prevalence of nephropathy in diabetic patients across the North American region. Eligible studies were screened out from 3 electronic databases, for example, PubMed, Google Scholar, and ScienceDirect using specific search keywords based on the eligibility criteria. Extracting the data from the included studies publication bias, quality assessment, outlier investigation, and meta-analysis was done followed by the subgroup analysis. A total of 11 studies met the study inclusion criteria. Meta-analysis was performed with the extracted data. Pooled prevalence of 28.2% (95% confidence interval [CI]: 19.7-36.7) with a high rate of heterogeneity (I2 = 100%) was identified. The pooled prevalence of nephropathy among diabetic patients in the United States of America, Canada, and Mexico was 24.2% (95% CI: 13.8-34.5), 31.2% (95% CI: 25.8-36.5), and 31.1% (95% CI: 20.8-41.5), respectively. The prevalence of nephropathy among diabetic patients was found lower in the United States of America as compared to Canada and Mexico. Besides, the pooled prevalence of the North American region was found to be lower as compared to the African, European, and Asian regions. Minimizing the pathogenic factors, sufficient diagnostic, healthcare facilities, and awareness are recommended to improve the situation.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3
ISSN:	0025-7974 1536-5964 1536-5964
DOI:	10.1097/MD.0000000000039759