Search Results - "Arman, Monica"
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Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications
Published in Expert reviews in molecular medicine (26-05-2009)“…Severe malaria has a high mortality rate (15-20%) despite treatment with effective antimalarial drugs. Adjunctive therapies for severe malaria that target the…”
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Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets
Published in Clinical proteomics (05-01-2022)“…Thrombocytopenia is frequent in Plasmodium vivax malaria but the role of platelets in pathogenesis is unknown. Our study explores the platelet (PLT) proteome…”
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Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands
Published in Biochemical journal (15-06-2015)“…Platelets are activated by a range of stimuli that share little or no resemblance in structure to each other or to recognized ligands, including diesel exhaust…”
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Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites
Published in PLoS pathogens (01-04-2012)“…Sequence diversity in pathogen antigens is an obstacle to the development of interventions against many infectious diseases. In malaria caused by Plasmodium…”
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Experimental conditions affect the outcome of Plasmodium falciparum platelet-mediated clumping assays
Published in Malaria journal (24-11-2008)“…Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes (IE) is a parasite adhesion phenotype that has been associated with severe malaria in…”
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Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes is associated with high parasitemia but not severe clinical manifestations of malaria in African children
Published in The American journal of tropical medicine and hygiene (01-11-2007)“…Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is an adhesive phenotype commonly found in field isolates that has previously been…”
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The human CD6 gene is transcriptionally regulated by RUNX and Ets transcription factors in T cells
Published in Molecular immunology (01-07-2009)“…CD6 is a lymphocyte surface receptor involved in lymphocyte activation and differentiation processes that is constitutively expressed on developing and mature…”
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In Vitro Inhibition of Plasmodium falciparum Rosette Formation by Curdlan Sulfate
Published in Antimicrobial Agents and Chemotherapy (01-04-2007)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
Published in Proceedings of the National Academy of Sciences - PNAS (26-06-2012)“…Cerebral malaria is the most deadly manifestation of infection with Plasmodium falciparum . The pathology of cerebral malaria is characterized by the…”
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Transcriptional Regulation of Human CD5: Important Role of Ets Transcription Factors in CD5 Expression in T Cells
Published in The Journal of immunology (1950) (15-06-2004)“…CD5 is a surface receptor constitutively expressed on thymocytes and mature T and B-1a cells. CD5 expression is tightly regulated during T and B cell…”
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Bruton's Tyrosine Kinase Inhibitors Impair FcγRIIA-Driven Platelet Responses to Bacteria in Chronic Lymphocytic Leukemia
Published in Frontiers in immunology (29-11-2021)“…Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with…”
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Practical Considerations of Dissolved Oxygen Levels for Platelet Function under Hypoxia
Published in International journal of molecular sciences (08-12-2021)“…Investigating human platelet function in low-oxygen environments is important in multiple settings, including hypobaric hypoxia (e.g., high altitude), sea…”
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A method for positive and negative selection of Plasmodium falciparum platelet-mediated clumping parasites and investigation of the role of CD36
Published in PloS one (06-02-2013)“…Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes (IEs) is a frequently observed parasite adhesion phenotype. The importance of…”
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Bruton’s Tyrosine Kinase Inhibitors Impair Fcγriia-Mediated Responses of Healthy Donor Platelets and Chronic Lymphocytic Leukaemia Derived Platelets to Bacteria
Published in Blood (05-11-2020)“…Platelets play a key role in innate immunity and can interact with bacteria through multiple molecular mechanisms. One key receptor for platelet-bacteria…”
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Role of Two Conserved Cytoplasmic Threonine Residues (T410 and T412) in CD5 Signaling
Published in The Journal of immunology (1950) (01-01-2001)“…CD5 is a transmembrane coreceptor that modulates activation and differentiation signals mediated by the Ag-specific receptor present on both T and B1a…”
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Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4
Published in Blood (15-05-2014)“…Bacterial adhesion to platelets is mediated via a range of strain-specific bacterial surface proteins that bind to a variety of platelet receptors. It is…”
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Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3
Published in Platelets (Edinburgh) (17-08-2016)“…Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct…”
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Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases
Published in European journal of immunology (01-04-2001)“…The human CD5 lymphocyte cell surface co‐receptor modulates activation and differentiation responses mediated by the antigen‐specific receptor of T and B…”
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Cloning of S4D-SRCRB, a new soluble member of the group B scavenger receptor cysteine-rich family (SRCR-SF) mapping to human chromosome 7q11.23
Published in Immunogenetics (New York) (01-12-2002)“…The scavenger receptor cysteine-rich superfamily (SRCR-SF) is a highly conserved group of membrane and/or secreted proteins related to the innate and adaptive…”
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