Prevalence of Metabolic Syndrome in Primary Hyperparathyroidism

Prevalence of Metabolic Syndrome in Primary Hyperparathyroidism

Aim: In this study, we aimed to evaluate the prevalence of metabolic syndrome (MetS), metabolic abnormalities and independent predictors of MetS in primary hyperparathyroidism and to contribute to long-term follow-up and management of these patients. Methods: Seventy-eight non-pregnant patients aged...

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Bibliographic Details
Published in:Haseki tıp bülteni Vol. 55; no. 2; pp. 131 - 136
Main Authors: Çevik, Gökçen Tuğba, Güldiken, Sibel, Soysal Atile, Neslihan, Çelik, Hüseyin, Çelik, Mehmet, Aytürk, Semra, Süt, Necdet, Armağan Tuğrul, Ayşe
Format: Journal Article
Language:English
Published: Istanbul Haseki Eğitim ve Araştırma Hastanesi 01-06-2017
Galenos Publishing House
Galenos Yayinevi
Subjects:
Blood pressure
Cardiovascular disease
Cholesterol
Diabetes
Ethics
Fasting
Health risk assessment
Hypertension
Males
Metabolic syndrome
Morbidity
Mortality
Osteoporosis
parathyroid hormon
Primary hyperparathyroidism
Sağlık Hizmetleri
Substance abuse treatment
Systemic diseases
Tıp
İstanbul
Türkiye
metabolic syndrome
Primary hyperparathyroidism
paratiroid hormon
parathyroid hormon
metabolik sendrom
Primer hiperparatiroidi
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Summary:Aim: In this study, we aimed to evaluate the prevalence of metabolic syndrome (MetS), metabolic abnormalities and independent predictors of MetS in primary hyperparathyroidism and to contribute to long-term follow-up and management of these patients. Methods: Seventy-eight non-pregnant patients aged 18 years and over without renal or hepatic failure and other systemic diseases, who were diagnosed with primary hyperparathyroidism, between January 2005 and December 2014 were included in the study. Results: Sixty-two (79.5%) subjects were female and 16 (20.5%) were male. The mean age of the patients was 55.3±12.6 years. Fifty eight patients were classified as symptomatic and 20 as asymptomatic. Thirtytwo patients (41%) were found to have primary hyperparathyroidism in accordance with the modified National Cholesterol Education Program- Adult Treatment Panel III criteria. The frequency of urinary tract stone disease was significantly higher in patients with hyperparathyroidism with MetS than in those with primary hyperparathyroidism without MetS (p=0.018). Conclusion: In our study, the prevalence of MetS in patients with primary hyperparathyroidism was found to be similar to that demonstrated in epidemiological studies performed in the general population of the same age. However, in these patients higher prevalence of hypertension, increased waist circumference, lipid disorders such as some syndrome abnormalities that may lead to the increased cardiovascular morbidity and mortality were observed.
ISSN:1302-0072
2147-2688
DOI:10.4274/haseki.3493