Search Results - "Arkal, Arjun Rao"
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Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
Published in Cell reports (Cambridge) (24-05-2022)“…Tissue-resident macrophages adapt to local signals within tissues to acquire specific functions. Neoplasia transforms the tissue, raising the question as to…”
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Increased risk of severe clinical course of COVID-19 in carriers of HLA-C04:01
Published in EClinicalMedicine (01-10-2021)“…Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there has been increasing urgency to identify pathophysiological characteristics…”
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Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer's Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions
Published in Frontiers in aging neuroscience (27-04-2022)“…Alzheimer's Disease (AD) is a complex neurodegenerative disease that gravely affects patients and imposes an immense burden on caregivers. Apolipoprotein E4…”
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4
Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
Published in Cancer cell (13-06-2022)“…T cell exhaustion is a major impediment to antitumor immunity. However, it remains elusive how other immune cells in the tumor microenvironment (TME)…”
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5
Toil enables reproducible, open source, big biomedical data analyses
Published in Nature biotechnology (01-04-2017)Get full text
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6
Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions
Published in Molecular neurobiology (01-01-2022)“…Alzheimer’s disease (AD) is a pervasive neurodegenerative disorder that disproportionately affects women. Since neural anatomy and disease pathophysiology…”
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Journal Article -
7
Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
Published in Cell reports (Cambridge) (24-05-2022)“…Tissue-resident macrophages adapt to local signals within tissues to acquire specific functions. Neoplasia transforms the tissue, raising the question as to…”
Get full text
Journal Article -
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SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants
Published in Stem cell reports (14-03-2023)“…Ancestral SARS coronavirus-2 (SARS-CoV-2) and variants of concern (VOC) caused a global pandemic with a spectrum of disease severity. The mechanistic…”
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Prediction of T-Cell Epitopes for Cancer Therapy
Published 01-01-2018“…The human immune system can identify malfunctioning, damaged, or infected cells within the body. The integrity of nucleated cells is communicated to the immune…”
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Dissertation