Search Results - "Aristizabal, Maria"

Biological embedding of experience: A primer on epigenetics by Aristizabal, Maria J., Anreiter, Ina, Halldorsdottir, Thorhildur, Odgers, Candice L., McDade, Thomas W., Goldenberg, Anna, Mostafavi, Sara, Kobor, Michael S., Binder, Elisabeth B., Sokolowski, Marla B., O’Donnell, Kieran J.

“…Biological embedding occurs when life experience alters biological processes to affect later life health and well-being. Although extensive correlative data…”
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Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip by Chan, Yujia A, Aristizabal, Maria J, Lu, Phoebe Y T, Luo, Zongli, Hamza, Akil, Kobor, Michael S, Stirling, Peter C, Hieter, Philip

“…DNA:RNA hybrid formation is emerging as a significant cause of genome instability in biological systems ranging from bacteria to mammals. Here we describe the…”
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Rapid cold hardening modifies ion regulation to delay anoxia-induced spreading depolarization in the CNS of the locust by Srithiphaphirom, Phinyaphat, Wang, Yuyang, Aristizabal, Maria J., Robertson, R. Meldrum

“…Insects experience different kinds of environmental stresses that can impair neural performance, leading to spreading depolarization (SD) of nerve cells and…”
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Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation by Gatev, Evan, Inkster, Amy M, Negri, Gian Luca, Konwar, Chaini, Lussier, Alexandre A, Skakkebaek, Anne, Sokolowski, Marla B, Gravholt, Claus H, Dunn, Erin C, Kobor, Michael S, Aristizabal, Maria J

“…Abstract Sex is a modulator of health that has been historically overlooked in biomedical research. Recognizing this knowledge gap, funding agencies now…”
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R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants by Stirling, Peter C, Chan, Yujia A, Minaker, Sean W, Aristizabal, Maria J, Barrett, Irene, Sipahimalani, Payal, Kobor, Michael S, Hieter, Philip

“…Genome instability via RNA:DNA hybrid-mediated R loops has been observed in mutants involved in various aspects of transcription and RNA processing. The…”
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RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability by Chang, Emily Yun-Chia, Novoa, Carolina A, Aristizabal, Maria J, Coulombe, Yan, Segovia, Romulo, Chaturvedi, Richa, Shen, Yaoqing, Keong, Christelle, Tam, Annie S, Jones, Steven J M, Masson, Jean-Yves, Kobor, Michael S, Stirling, Peter C

“…Sgs1, the orthologue of human Bloom's syndrome helicase BLM, is a yeast DNA helicase functioning in DNA replication and repair. We show that loss increases…”
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MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts by Chang, Emily Yun-Chia, Tsai, Shuhe, Aristizabal, Maria J., Wells, James P., Coulombe, Yan, Busatto, Franciele F., Chan, Yujia A., Kumar, Arun, Dan Zhu, Yi, Wang, Alan Ying-Hsu, Fournier, Louis-Alexandre, Hieter, Philip, Kobor, Michael S., Masson, Jean-Yves, Stirling, Peter C.

“…Ectopic R-loop accumulation causes DNA replication stress and genome instability. To avoid these outcomes, cells possess a range of anti-R-loop mechanisms,…”
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Leveraging Gene Redundancy to Find New Histone Drivers in Cancer by Ostroverkhova, Daria, Espiritu, Daniel, Aristizabal, Maria J, Panchenko, Anna R

“…Histones play a critical role in chromatin function but are susceptible to mutagenesis. In fact, numerous mutations have been observed in several cancer types,…”
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Pharmacological Treatment for Dialysis‐Related Muscle Cramps: A Systematic Review by Mantilla‐Manosalva, Nidia, Guadarrama, Santiago, Bedoya‐Muñoz, Lennis Jazmin, Giraldo‐Moreno, Sara, Cuellar‐Valencia, Laura, Iriarte‐Aristizábal, María Fernanda, León, Marta Ximena, Mendoza‐Montenegro, Fernan Alejandro, Correa‐Morales, Juan Esteban

“…ABSTRACT Background Patients with end‐stage renal disease undergoing dialysis suffer from muscle cramps, a prevalent and burdensome symptom for which there is…”
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Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study by Li, Hang, Ryu, Min Hyung, Rider, Christopher F., Tse, Wayne, Clifford, Rachel L., Aristizabal, Maria J., Wen, Weiping, Carlsten, Chris

“…Epidemiological data show that traffic-related air pollution contributes to the increasing prevalence and severity of asthma. DNA methylation (DNAm) changes…”
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An important role for triglyceride in regulating spermatogenesis by Chao, Charlotte F, Pesch, Yanina-Yasmin, Yu, Huaxu, Wang, Chenjingyi, Aristizabal, Maria J, Huan, Tao, Tanentzapf, Guy, Rideout, Elizabeth

“…is a powerful model to study how lipids affect spermatogenesis. Yet, the contribution of neutral lipids, a major lipid group which resides in organelles called…”
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Cancer and Non-cancer Fatigue Treated With Bupropion: A Systematic Review by Correa-Morales, Juan Esteban, Cuellar-Valencia, Laura, Mantilla-Manosalva, Nidia, Quintero-Muñoz, Elias, Iriarte-Aristizábal, María Fernanda, Giraldo-Moreno, Sara, Rodríguez-Campos, Luisa Fernanda

“…Fatigue is a predominant and distressing symptom in cancer and non-cancer conditions for which there is a paucity of recommendations for pharmacological…”
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The impact of coupling a dynamic ocean in the Hurricane Analysis and Forecast System by Gramer, Lewis J., Steffen, John, Aristizabal Vargas, Maria, Kim, Hyun-Sook

“…Coupling a three-dimensional ocean circulation model to an atmospheric model can significantly improve forecasting of tropical cyclones (TCs). This is…”
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Uncrewed Ocean Gliders and Saildrones Support Hurricane Forecasting and Research by Miles, Travis N., Zhang, Dongxiao, Foltz, Gregory R., Zhang, Jun A., Meinig, Christian, Bringas, Francis, Triñanes, Joaquin, Le Hénaff, Matthieu, Vargas, Maria F. Aristizabal, Coakley, Sam, Edwards, Catherine R., Gong, Donglai, Todd, Robert E., Oliver, Matthew J., Wilson, W. Douglas, Whilden, Kerri, Kirkpatrick, Barbara, Chardon-Maldonado, Patricia, Morell, Julio M., Hernandez, Debra, Kuska, Gerhard, Stienbarger, Cheyenne D., Bailey, Kathleen, Zhang, Chidong, Glenn, Scott M., Goni, Gustavo J.

“…Miles et al focus on uncrewed ocean gliders and saildrones support hurricane forecasting and research. Components of the sustained ocean observing system are…”
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The RNAPII-CTD Maintains Genome Integrity through Inhibition of Retrotransposon Gene Expression and Transposition by Aristizabal, Maria J, Negri, Gian Luca, Kobor, Michael S

“…RNA polymerase II (RNAPII) contains a unique C-terminal domain that is composed of heptapeptide repeats and which plays important regulatory roles during gene…”
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Regulation of Skn7-dependent, oxidative stress-induced genes by the RNA polymerase II-CTD phosphatase, Fcp1, and Mediator kinase subunit, Cdk8, in yeast by Aristizabal, Maria J., Dever, Kristy, Negri, Gian Luca, Shen, Mary, Hawe, Nicole, Benschop, Joris J., Holstege, Frank C.P., Krogan, Nevan J., Sadowski, Ivan, Kobor, Michael S.

“…Fcp1 is a protein phosphatase that facilitates transcription elongation and termination by dephosphorylating the C-terminal domain of RNA polymerase II…”
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A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans by Lu, Phoebe Y T, Kirlin, Alyssa C, Aristizabal, Maria J, Brewis, Hilary T, Lévesque, Nancy, Setiaputra, Dheva T, Avvakumov, Nikita, Benschop, Joris J, Groot Koerkamp, Marian, Holstege, Frank C P, Krogan, Nevan J, Yip, Calvin K, Côté, Jacques, Kobor, Michael S

“…Abstract The NuA4 lysine acetyltransferase complex acetylates histone and nonhistone proteins and functions in transcription regulation, cell cycle…”
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Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression by Konwar, Chaini, Asiimwe, Rebecca, Inkster, Amy M, Merrill, Sarah M, Negri, Gian L, Aristizabal, Maria J, Rider, Christopher F, MacIsaac, Julie L, Carlsten, Christopher, Kobor, Michael S

“…Understanding the molecular basis of susceptibility factors to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health…”
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Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome by Steunou, Anne-Lise, Cramet, Myriam, Rossetto, Dorine, Aristizabal, Maria J., Lacoste, Nicolas, Drouin, Simon, Côté, Valérie, Paquet, Eric, Utley, Rhea T., Krogan, Nevan, Robert, François, Kobor, Michael S., Côté, Jacques

“…Recognition of histone marks by reader modules is thought to be at the heart of epigenetic mechanisms. These protein domains are considered to function by…”
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A successful campaign to increase use of the sepsis order set in the emergency department by Berlyand, Yosef, Black, Lauren, Lee, Andy Hung-Yi, Aaronson, Emily L., Copenhaver, Martin S., Filbin, Michael R., Mort, Elizabeth A., Dutta, Sayon, Rhee, Chanu, Hibbert, Kathryn A., Turno, Douglas-Jarrett Cole, Durocher, Kara E., Aristizabal, Maria E., Sonis, Jonathan D.

“…Standardizing and improving sepsis treatment has become a priority of hospital leaders nationwide [7]. Per a patient-level logistic regression model estimating…”
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