Search Results - "Arion, Dominique"

Transcriptome alterations in prefrontal pyramidal cells distinguish schizophrenia from bipolar and major depressive disorders by Arion, Dominique, Huo, Zhiguang, Enwright, John F, Corradi, John P, Tseng, George, Lewis, David A

“…Abstract Background Impairments in certain cognitive processes (e.g., working memory) are typically most pronounced in schizophrenia (SZ), intermediate in…”
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Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia by Datta, Dibyadeep, Arion, Dominique, Corradi, John P, Lewis, David A

“…Abstract Background Cognitive dysfunction in schizophrenia is associated with a lower density of dendritic spines on deep layer 3 pyramidal cells in the…”
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Cortical Deficits of Glutamic Acid Decarboxylase 67 Expression in Schizophrenia: Clinical, Protein, and Cell Type-Specific Features by Curley, Allison A., Arion, Dominique, Volk, David W., Asafu-Adjei, Josephine K., Sampson, Allan R., Fish, Kenneth N., Lewis, David A.

“…Depression was associated with increased inflammation as measured by elevated levels of interleukin-6 and high-sensitivity C-reactive protein in patients with…”
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Molecular Evidence for Increased Expression of Genes Related to Immune and Chaperone Function in the Prefrontal Cortex in Schizophrenia by Arion, Dominique, Unger, Travis, Lewis, David A, Levitt, Pat, Mirnics, Károly

“…Background Schizophrenia is characterized by complex gene expression changes. The transcriptome alterations in the prefrontal cortex have been the subject of…”
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Dysregulated ErbB4 Splicing in Schizophrenia: Selective Effects on Parvalbumin Expression by Chung, Daniel W., Volk, David W., Arion, Dominique, Zhang, Yun, Sampson, Allan R., Lewis, David A.

“…Objective:Alternative splicing of ErbB4 transcripts is dysregulated in the dorsolateral prefrontal cortex in schizophrenia. ErbB4 regulates the activity of…”
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Distinct Properties of Layer 3 Pyramidal Neurons from Prefrontal and Parietal Areas of the Monkey Neocortex by González-Burgos, Guillermo, Miyamae, Takeaki, Krimer, Yosef, Gulchina, Yelena, Pafundo, Diego E, Krimer, Olga, Bazmi, Holly, Arion, Dominique, Enwright, John F, Fish, Kenneth N, Lewis, David A

“…In primates, working memory function depends on activity in a distributed network of cortical areas that display different patterns of delay task-related…”
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Altered Expression of ARP2/3 Complex Signaling Pathway Genes in Prefrontal Layer 3 Pyramidal Cells in Schizophrenia by Datta, Dibyadeep, Arion, Dominique, Roman, Kaitlyn M, Volk, David W, Lewis, David A

“…Objective:Lower dendritic spine density on layer 3 pyramidal cells in the dorsolateral prefrontal cortex (DLPFC) appears to contribute to cognitive dysfunction…”
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Perisomatic inhibition and cortical circuit dysfunction in schizophrenia by Lewis, David A, Fish, Kenneth N, Arion, Dominique, Gonzalez-Burgos, Guillermo

“…Highlights ► Cognitive deficits in schizophrenia are associated with altered gamma oscillations. ► Paralbumin basket neurons generate cortical gamma…”
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GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons by Garst-Orozco, Jonathan, Malik, Ruchi, Lanz, Thomas A, Weber, Mark L, Xi, Hualin, Arion, Dominique, Enwright, John F, Lewis, David A, O'Donnell, Patricio, Sohal, Vikaas S, Buhl, Derek L

“…Deficits in fast-spiking inhibitory interneurons (FSINs) within the dorsolateral prefrontal cortex (dlPFC) are hypothesized to underlie cognitive impairment…”
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Protracted Developmental Trajectories of GABAA Receptor α1 and α2 Subunit Expression in Primate Prefrontal Cortex by HASHIMOTO, Takanori, NGUYEN, Quyen L, ROTARU, Diana, KEENAN, Tanya, ARION, Dominique, BENEYTO, Monica, GONZALEZ-BURGOS, Guillermo, LEWIS, David A

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Lower Gene Expression for KCNS3 Potassium Channel Subunit in Parvalbumin-Containing Neurons in the Prefrontal Cortex in Schizophrenia by Georgiev, Danko, Arion, Dominique, Enwright, John F, Kikuchi, Mitsuru, Minabe, Yoshio, Corradi, John P, Lewis, David A, Hashimoto, Takanori

“…ObjectiveIn schizophrenia, alterations in markers of cortical GABA neurotransmission are prominent in parvalbumin-containing neurons. Parvalbumin neurons…”
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Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits by Datta, Dibyadeep, Enwright, John F, Arion, Dominique, Paspalas, Constantinos D, Morozov, Yury M, Lewis, David A, Arnsten, Amy F T

“…cAMP signaling has powerful, negative effects on cognitive functions of the primate dorsolateral prefrontal cortex (dlPFC), opening potassium channels to…”
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Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: Signature of altered neural development? by Arion, Dominique, Horváth, Szatmár, Lewis, David A, Mirnics, Károly

“…Abstract The development of the human neocortex gives rise to a complex cytoarchitecture, grouping together cells with similar structure, connectivity and…”
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Molecular markers distinguishing supragranular and infragranular layers in the human prefrontal cortex by Arion, Dominique, Unger, Travis, Lewis, David A., Mirnics, Károly

“…The human neocortex is organized into six layers that are differentiated by the size and packing density of their constituent neurons. The gene products that…”
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Phenotypic Mechanism of HIV-1 Resistance to 3‘-Azido-3‘-deoxythymidine (AZT):  Increased Polymerization Processivity and Enhanced Sensitivity to Pyrophosphate of the Mutant Viral Reverse Transcriptase by Arion, Dominique, Kaushik, Neerja, McCormick, Suzanne, Borkow, Gadi, Parniak, Michael A

“…The multiple mutations associated with high-level AZT resistance (D67N, K70R, T215F, K219Q) arise in two separate subdomains of the viral reverse transcriptase…”
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Correlation of transcriptome profile with electrical activity in temporal lobe epilepsy by Arion, Dominique, Sabatini, Michael, Unger, Travis, Pastor, Jesús, Alonso-Nanclares, Lidia, Ballesteros-Yáñez, Inmaculada, García Sola, Rafael, Muñoz, Alberto, Mirnics, Károly, DeFelipe, Javier

“…The biology underlying epileptic brain activity in humans is not well understood and likely depends on changes in gene expression. We performed a microarray…”
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Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors by Sluis-Cremer, Nicolas, Arion, Dominique, Parniak, Michael A

“…N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone (BBNH) inhibits both the DNA polymerase and ribonuclease H (RNase H) activities of the human…”
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The M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Impairs Rescue of Chain-Terminated DNA Synthesis by Götte, M, Arion, D, Parniak, M A, Wainberg, M A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Synthesis and Biophysical Properties of Arabinonucleic Acids (ANA):  Circular Dichroic Spectra, Melting Temperatures, and Ribonuclease H Susceptibility of ANA·RNA Hybrid Duplexes by Noronha, Anne M, Wilds, Christopher J, Lok, Chun-Nam, Viazovkina, Katya, Arion, Dominique, Parniak, Michael A, Damha, Masad J

“…Arabinonucleic acid (ANA), the 2‘-epimer of RNA, was synthesized from arabinonucleoside building blocks by conventional solid-phase phosphoramidite synthesis…”
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Developmental Expression Patterns of GABA A Receptor Subunits in Layer 3 and 5 Pyramidal Cells of Monkey Prefrontal Cortex by Datta, Dibyadeep, Arion, Dominique, Lewis, David A.

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