Search Results - "Arimoto, Sakae"

Chemo-preventive effects and antitumorigenic mechanisms of beer and nonalcoholic beer toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) - induced lung tumorigenesis in A/J mice by Takata, Jun, Kiura, Katsuyuki, Nakasuka, Takamasa, Hirabae, Atsuko, Arimoto-Kobayashi, Sakae

“…We investigated the chemopreventive effects of beer, nonalcoholic beers (NABs), and beer-components (glycine betaine (GB)) on NNK-induced lung tumorigenesis in…”
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Antimutagenic, anti-inflammatory, and antioxidative activities of the juice of Vitis ficifolia var. Ganebu, a woody vine in the grape family, known as Ryukyu-ganebu in Japan by Arimoto-Kobayashi, Sakae, Hida, Ryoko, Fujii, Nana, Mochioka, Ryosuke

“…Abstract Background Mutation, inflammation, and oxidative damage including lipid-peroxidation are factors involved in the development of cancer. We…”
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Chemopreventive effects and anti-tumorigenic mechanisms of Actinidia arguta, known as sarunashi in Japan toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)- induced lung tumorigenesis in a/J mouse by Takata, Jun, Miyake, Naoko, Saiki, Yusuke, Tada, Misako, Sasaki, Kensuke, Kubo, Toshio, Kiura, Katsuyuki, Arimoto-Kobayashi, Sakae

“…Previously, we reported the inhibitory effect of Actinidia arguta juice, known as sarunashi juice (sar-j) in Japan, on mutagenesis, inflammation, and mouse…”
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Indolo[3,2-b]quinoline Derivatives Suppressed the Hemolytic Activity of Beta-Pore Forming Toxins, Aerolysin-Like Hemolysin Produced by Aeromonas sobria and Alpha-Hemolysin Produced by Staphylococcus aureus by Takahashi, Eizo, Fujinami, Chiaki, Kuroda, Teruo, Takeuchi, Yasuo, Miyoshi, Shin-ichi, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…In an attempt to discover inhibitory compounds against pore-forming toxins, some of the major toxins produced by bacteria, we herein examined the effects of…”
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Properties of hemolysin and protease produced by Aeromonas trota by Takahashi, Eizo, Ozaki, Haruka, Fujii, Yoshio, Kobayashi, Hidetomo, Yamanaka, Hiroyasu, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…We examined the properties of exotoxins produced by Aeromonas trota (A. enteropelogenes), one of the diarrheagenic species of Aeromonadaceae. Nine of 19 A…”
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Protective effect of Actinidia arguta in MPTP-induced Parkinson’s disease model mice by Kitamura, Yuki, Sakanashi, Mayuko, Ozawa, Azuki, Saeki, Yuri, Nakamura, Ayano, Hara, Yuiho, Saeki, Ken-ichi, Arimoto-Kobayashi, Sakae

“…Parkinson’s disease (PD) is a neurodegenerative disease characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra…”
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Analysis of Carboxy Terminal Domain of Metalloprotease of Elastolytic Aeromonas hydrophila by Takahashi, Eizo, Kobayashi, Hidetomo, Yamanaka, Hiroyasu, Nakanishi, Mayu, Tateishi, Arisa, Abe, Takemi, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…We examined the ability of Aeromonas hydrophila to lyse elastin. Eight of 13 strains showed elastolytic activity on agar medium containing elastin and 5…”
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Chloroethylating anticancer drug-induced mutagenesis and its repair in Escherichia coli by Yamada, Yoko, Watanabe, Shinji, Okamoto, Keinosuke, Arimoto, Sakae, Takahashi, Eizo, Negishi, Kazuo, Negishi, Tomoe

“…Chloroethylnitrosourea (CENU) derivatives, such as nimustine (ACNU) and carmustine (BCNU), are employed in brain tumor chemotherapy due to their ability to…”
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Spermidine-Analogous Triamines Suppressed the Growth of Candida albicans by Takahashi, Eizo, Oono, Seiji, Yamamoto, Shigeo, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…We examined the antifungal activity of various synthetic triamines on several fungi. Among various triamines having a general structure H2N(CH2)aNH(CH2)bNH2…”
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Elimination of mutagenic contaminants from water using cellulose bearing ferrous-phthalocyanine by Sano, Kayoko, Soga, Yuka, Ohta, Kaori, Kitamura, Yuki, Arimoto-Kobayashi, Sakae

“…We previously investigated methods for separating mutagenic contaminants from aqueous solutions using cellulose-bearing covalently bound…”
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2,6-Dimethoxy-1,4-benzoquinone, isolation and identification of anti-carcinogenic, anti-mutagenic and anti-inflammatory component from the juice of Vitis coignetiae by Kamiya, Tomonori, Tanimoto, Yusuke, Fujii, Nana, Negishi, Tomoe, Suzuki, Toshinori, Hatano, Tsutomu, Arimoto-Kobayashi, Sakae

“…Previously we demonstrated the anti-tumorigenic, anti-mutagenic and anti-inflammatory effects of the juice of Vitis coignetiae (yamabudo), and identified…”
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Chemopreventive effects and anti-tumorigenic mechanisms of 2,6-dimethoxy-1,4-benzoquinone, a constituent of Vitis coignetiae Pulliat (crimson glory vine, known as yamabudo in Japan), toward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice by Arimoto-Kobayashi, Sakae, Sasaki, Kensuke, Hida, Ryoko, Miyake, Naoko, Fujii, Nana, Saiki, Yusuke, Daimaru, Kyohei, Nakashima, Hirono, Kubo, Toshio, Kiura, Katsuyuki

“…Previously, we isolated and identified anti-mutagenic and anti-inflammatory components from Vitis coignetiae (crimson glory vine, known as yamabudo in Japan)…”
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Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells by Horinouchi, Mayumi, Arimoto-Kobayashi, Sakae

“…Photochemical genotoxicity was evaluated in human keratinocyte NCTC2544 cells. The cells were pre-treated with photogenotoxic or pseudophotoclastogenic…”
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RXR Partial Agonist Produced by Side Chain Repositioning of Alkoxy RXR Full Agonist Retains Antitype 2 Diabetes Activity without the Adverse Effects by Kawata, Kohei, Morishita, Ken-ichi, Nakayama, Mariko, Yamada, Shoya, Kobayashi, Toshiki, Furusawa, Yuki, Arimoto-Kobayashi, Sakae, Oohashi, Toshitaka, Makishima, Makoto, Naitou, Hirotaka, Ishitsubo, Erika, Tokiwa, Hiroaki, Tai, Akihiro, Kakuta, Hiroki

“…We previously reported RXR partial agonist CBt-PMN (1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid: 5, EC50 = 143…”
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Production and properties of lipase of Aeromonas sobria by Takahashi, Eizo, Ito, Hidenobu, Kobayashi, Hidetomo, Yamanaka, Hiroyasu, Takeda, Yoshifumi, Balakrish Nair, Gopinath, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…ABSTRACT  Aeromonas have been isolated from a wide variety of aquatic environments. However the number of Aeromonas in sea water is extremely small compared to…”
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Maturation pathway of metalloprotease produced by Aeromonas sobria by Takahashi, Eizo, Fujii, Yoshio, Kobayashi, Hidetomo, Yamanaka, Hiroyasu, Nair, Gopinath Balakrish, Takeda, Yoshifumi, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…ABSTRACT Previously, we cloned the metalloprotease gene of Aeromonas sobria (amp) and determined its nucleotide sequence (GenBank accession number DQ784565)…”
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Inhibition of biosynthesis of metalloprotease of Aeromonas sobria by sodium chloride in the medium by Takahashi, Eizo, Kobayashi, Hidetomo, Yamanaka, Hiroyasu, Nair, Gopinath Balakrish, Takeda, Yoshifumi, Arimoto, Sakae, Negishi, Tomoe, Okamoto, Keinosuke

“…ABSTRACT The present authors have previously shown that the serine protease activity of Aeromonas sobria is markedly decreased when A. sobria is cultured in…”
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Increase of somatic cell mutations in oxidative damage-sensitive drosophila by Koike, Ryota, Uchiyama, Tomoyo, Arimoto-Kobayashi, Sakae, Okamoto, Keinosuke, Negishi, Tomoe

“…Oxidative damage is an important genotoxic source for almost all organisms. To efficiently detect mutations induced by oxidative damage, we previously…”
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Somatic-cell mutation induced by short exposures to cigarette smoke in urate-null, oxidative stress-sensitive Drosophila by Uchiyama, Tomoyo, Koike, Ryota, Yuma, Yoko, Okamoto, Keinosuke, Arimoto-Kobayashi, Sakae, Suzuki, Toshinori, Negishi, Tomoe

“…We previously reported that a urate-null strain of Drosophila is hypersensitive to cigarette smoke (CS), and we suggested that CS induces oxidative stress in…”
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Inhibitory effect of Actinidia arguta on mutagenesis, inflammation and two-stage mouse skin tumorigenesis by Nishimura, Mari, Okimasu, Yuma, Miyake, Naoko, Tada, Misako, Hida, Ryoko, Negishi, Tomoe, Arimoto-Kobayashi, Sakae

“…, known as sarunashi in Japan, is a vine tree native to east-Asia, including Japan, that produces small fruit rich in anthocyanins, catechins, vitamin C,…”
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