Search Results - "Arikawa, Koji"
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Strain-level profiling of viable microbial community by selective single-cell genome sequencing
Published in Scientific reports (15-03-2022)“…Culture-independent analysis with high-throughput sequencing has been widely used to characterize bacterial communities. However, signals derived from…”
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Uncultured prokaryotic genomes in the spotlight: An examination of publicly available data from metagenomics and single-cell genomics
Published in Computational and structural biotechnology journal (01-01-2023)“…Owing to the ineffectiveness of traditional culture techniques for the vast majority of microbial species, culture-independent analyses utilizing…”
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Target enrichment of uncultured human oral bacteria with phage-derived molecules found by single-cell genomics
Published in Journal of bioscience and bioengineering (01-07-2023)“…Advances in culture-independent microbial analysis, such as metagenomics and single-cell genomics, have significantly increased our understanding of microbial…”
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Revealing within-species diversity in uncultured human gut bacteria with single-cell long-read sequencing
Published in Frontiers in microbiology (24-02-2023)“…Obtaining complete and accurate bacterial genomes is vital for studying the characteristics of uncultured bacteria. Single-cell genomics is a promising…”
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Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast
Published in Nature communications (09-03-2020)“…How quiescent cells break dormancy is a key issue in eukaryotic cells including cancer. Fungal spores, for example, remain quiescent for long periods until…”
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Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity by RNA-seq analysis
Published in Scientific reports (28-04-2020)“…Bioprinting technology is expected to be applied in the fields of regenerative medicine and drug discovery. There are several types of bioprinters, especially…”
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Recovery of strain-resolved genomes from human microbiome through an integration framework of single-cell genomics and metagenomics
Published in Microbiome (12-10-2021)“…Background Obtaining high-quality (HQ) reference genomes from microbial communities is crucial for understanding the phylogeny and function of uncultured…”
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Effective microtissue RNA extraction coupled with Smart-seq2 for reproducible and robust spatial transcriptome analysis
Published in Scientific reports (27-04-2020)“…Spatial transcriptomics is useful for understanding the molecular organization of a tissue and providing insights into cellular function in a morphological…”
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Reproducible and sensitive micro-tissue RNA sequencing from formalin-fixed paraffin-embedded tissues for spatial gene expression analysis
Published in Scientific reports (14-11-2022)“…Spatial transcriptome analysis of formalin-fixed paraffin-embedded (FFPE) tissues using RNA-sequencing (RNA-seq) provides interactive information on morphology…”
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Exploring strain diversity of dominant human skin bacterial species using single-cell genome sequencing
Published in Frontiers in microbiology (05-08-2022)“…To understand the role of the skin commensal bacterial community in skin health and the spread of pathogens, it is crucial to identify genetic differences in…”
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Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts
Published in Disease models & mechanisms (01-06-2022)“…Gene expression analysis at the single-cell level by next-generation sequencing has revealed the existence of clonal dissemination and microheterogeneity in…”
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A single amplified genome catalog reveals the dynamics of mobilome and resistome in the human microbiome
Published in Microbiome (02-10-2024)“…The increase in metagenome-assembled genomes (MAGs) has advanced our understanding of the functional characterization and taxonomic assignment within the human…”
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Integrated spatial analysis of gene mutation and gene expression for understanding tumor diversity in formalin-fixed paraffin-embedded lung adenocarcinoma
Published in Frontiers in oncology (24-11-2022)“…A deeper understanding of intratumoral heterogeneity is essential for prognosis prediction or accurate treatment plan decisions in clinical practice. However,…”
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14
Vertical flow array chips reliably identify cell types from single-cell mRNA sequencing experiments
Published in Scientific reports (23-11-2016)“…Single-cell mRNA sequencing offers an unbiased approach to dissecting cell types as functional units in multicellular tissues. However, highly reliable cell…”
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A highly sensitive and accurate gene expression analysis by sequencing (“bead-seq”) for a single cell
Published in Analytical biochemistry (15-02-2015)“…Analyses of gene expressions in single cells are important for understanding detailed biological phenomena. Here, a highly sensitive and accurate method by…”
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Distinctive Regulation of Emotional Behaviors and Fear-Related Gene Expression Responses in Two Extended Amygdala Subnuclei With Similar Molecular Profiles
Published in Frontiers in molecular neuroscience (03-09-2021)“…The central nucleus of the amygdala (CeA) and the lateral division of the bed nucleus of the stria terminalis (BNST) are the two major nuclei of the central…”
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Is Word Order Asymmetry Mathematically Expressible?
Published in Biolinguistics (01-01-2013)“…The computational procedure for human natural language (CHL) shows an asymmetry in unmarked orders for S, O, and V. Following Lyle Jenkins, it is speculated…”
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Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice
Published in Cell reports (Cambridge) (09-04-2019)“…Severe invasive group A Streptococcus (GAS) infection evades anti-bacterial immunity by attenuating the cellular components of innate immune responses…”
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Cortical transcriptome analysis after spinal cord injury reveals the regenerative mechanism of central nervous system in CRMP2 knock-in mice
Published in Neural regeneration research (01-07-2021)“…Recent studies have shown that mutation at Ser522 causes inhibition of collapsin response mediator protein 2 (CRMP2) phosphorylation and induces axon…”
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Locality in Syntax and Floating Numeral Quantifiers
Published in Linguistic inquiry (01-10-2007)“…We defend the idea that a floating quantifier observes syntactic locality with its associated noun phrase. This idea has given rise to a number of important…”
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